Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C1291077 (bloating)
 1,674 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Inflammatory bowel disease is associated with many embarrassing symptoms: frequent, urgent, or bloody diarrhea; weight loss from malnutrition or weight gain from adverse effects of medicine; abdominal cramping and bloating; and occasionally incontinence. The course of the disease is often unpredictable, as the disease fluctuates between remission and flare-up. Because of the embarrassing nature and the unpredictability of the disease, many people feel stigmatized or perceive that they will be stigmatized because of their disease. For this study, 14 people with inflammatory bowel disease were interviewed about their experiences disclosing their disease to others. Although everyone perceived at some point that their disease would be stigmatizing, participants for the most part had very positive experiences once they shared their disease with others. Support and stigma are examined during initial diagnosis of the disease, romantic relationships, work and school, surgery, and medicine. Interviews were examined not only for common themes but also for overt situations of stigma, which were few in occurrence, but often had a strong impact on the person's life. Discussed are the implications of this discrepancy: people's perceptions of stigma do not always conform to their experience of stigma.
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PMID:Support often outweighs stigma for people with inflammatory bowel disease. 2469 Oct 83

Gastroparesis (GP) is a chronic, gastric dysmotility disorder with significant morbidity and mortality. The hallmark of GP is the delayed emptying of the contents of the stomach in the absence of any mechanical obstruction. Patients most commonly report chronic symptoms of nausea, vomiting, feeling full quickly when eating, bloating, and abdominal pain. Treatments are limited with relatively poor efficacy. As such, children with GP are at significant risk for the development of psychological co-morbidities. In this paper, we provide a topical review of the scientific literature on the psychological, social, and emotional impacts of gastroparesis in pediatric patients. We aim to document the current state of research, identify gaps in our knowledge with appropriate recommendations for future research directions, and highlight the unique challenges pediatric patients with GP and their families may face as they manage this disease. Based on the current review, research into the psychosocial impacts in children with GP is essentially non-existent. However, when considering research in children with other chronic digestive diseases, children with GP are likely to face multiple psychosocial challenges, including increased risk for anxiety and depression, stigma, and reduced quality of life. These significant gaps in the current understanding of effects of GP across domains of childhood functioning allow for ample opportunities for future studies to address psychosocial outcomes.
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PMID:The Scarcity of Literature on the Psychological, Social, and Emotional Effects of Gastroparesis in Children. 3287 88