Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1140680 (ovarian cancer)
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Human Gene/Protein
cell recognition molecule CASPR3 10.1
C1orf86 10.1
zinc finger CCCH-type containing 13 10.1
DPEP2 10.1
CDC42-binding protein kinase beta 10.1
ZNF498 10.1
kallikrein-related protein 10.1
MRPL46 10.1
AHCYL1 protein 10.1
podocan-like 1 10.1
HCA90 10.1
KLHL14 protein 10.1
carinoembryonic antigen 10.1
jumonji C domain containing histone demethylase 1 homolog D 10.1
MAGE12 10.1
Breast cancer 2, early onset 10.1
CAP 2 10.1
ATAD4 10.1
KIAA0419 gene product 10.1
GRAM domain containing 1B 10.1
MAPK10 protein 10.1
Histone H2B type 1-K 10.1
TNF superfamily, member 2 10.1
NXPH2 10.1
RNF20 protein 10.1
PLG protein 10.1
spectrin repeat containing, nuclear envelope 1 10.1
OR52M1 10.1
C4orf18 10.1
ACPP protein 10.1
C7orf34 10.1
LOC222171 10.1
AMPH1 10.1
Intermediate filament family orphan 1 10.1
elastin microfibril interfase located protein 10.1
PCDHB17 10.1
ZNF691 10.1
FAM27L 10.1
POTEC 10.1
Inhibitor of growth protein 2 10.1
coiled-coil and C2 domain containing 1A 10.1
OR2A1 10.1
C3orf38 10.1
Histone H2A type 1 10.1
polypeptide N-acetylgalactosaminyltransferase 14 10.1
COL11A1 protein 9.6
RNASE6PL 9.6
ABHD8 9.6
PRP4K 9.4
kallikrein 8 9.4
HE4 9.2
KCNMA1 protein 9.1
Ectodermal-neural cortex 9.1
MAGE-3b 9.1
LRRC46 9.1
ICB-1 9.1
HNRNPCL1 9.1
PRICKLE4 9.1
C16orf72 9.1
transient receptor potential channel 7 9.1
LOC134466 9.1
Chloride intracellular channel 3 9.1
HIST1H2BN 9.1
Opioid binding protein/cell adhesion molecule-like 9.1
TEKT5 9.1
Receptor protein tyrosine kinase 9.1
PSK-1 9.1
PCDHB3 9.1
NPIPL1 9.1
dual oxidase maturation factor 1 9.1
VATI 9.1
ZNF283 9.1
CORO2A 9.1
SLC22A16 protein 9.1
ZNF100 9.1
ARID3C 9.1
HOXC6 protein 9.1
KRCC1 9.1
C1orf38 9.1
Transketolase-like 1 9.1
more...
Disease
Arterial-enteric fistula 10.1
Peritoneal adenocarcinoma 10.1
Papillary serous endometrial carcinoma 10.1
Peritoneal carcinoma 10.1
ovarian cancer 10.1
Ovarian Neoplasm 10.1
Granulosa cell carcinoma 10.1
Ovarian Cancer 9.7
recurrent ovarian cancer 9.4
ovarian cancer stage 9.4
stage I ovarian cancer 9.3
metastatic ovarian cancer 9.2
carcinoma of the digestive system 9.1
LFS1 9.1
stage III ovarian cancer 9.1
stage I vaginal cancer 9.1
fallopian tube cancer 9.0
Ovarian adenocarcinoma 8.9
Hereditary Breast Cancer 8.8
epithelial ovarian cancer 8.7
Omental metastasis 8.7
Hereditary Breast and Ovarian Cancer 8.6
metastatic uterine cancer 8.6
stage IV cervical cancer 8.6
stage II ovarian cancer 8.6
peritoneal cancer 8.6
gynecologic cancer 8.5
ovarian serous cystadenocarcinoma 8.5
Contralateral breast cancer 8.4
Serous carcinoma 8.4
Serous surface papillary carcinoma 8.1
Peritoneal Carcinomatosis 8.1
Lynch Syndrome II 8.1
TB salpingitis 8.1
Freemartin 8.1
Secondary carcinoma 8.1
Radiation colitis 8.1
uterine corpus cancer 8.1
AD10 8.0
ovarian mucinous cystadenocarcinoma 8.0
Corpus uteri 8.0
Endometrioid carcinoma 7.9
Borderline ovarian tumor 7.9
malignant ascites 7.9
Benign neoplasm 7.8
Benign neoplasm 7.8
recurrent uterine sarcoma 7.8
Surgical menopause 7.7
ovarian tumors of low malignant potential 7.7
BRCAX 7.6
Inguinal lymphadenopathy 7.6
Carcinomatous peritonitis 7.6
Peritoneal Mesothelioma 7.6
cancer seeding 7.6
Gastrointestinal fistula 7.6
Peritoneal metastases 7.5
ovarian neoplasm 7.5
bilateral breast cancer 7.4
benign ovarian cyst 7.4
gynecologic neoplasm 7.4
FANCN 7.3
lower urinary tract cancer 7.3
ovarian endometrioid adenocarcinoma 7.3
Paraneoplastic cerebellar degeneration 7.2
fallopian tube 7.2
mesothelial neoplasm 7.1
Atypical endometrial hyperplasia 7.1
papillary serous carcinoma 7.1
HRA 7.1
Malignant acanthosis nigricans 7.1
FANCJ 7.0
Pulse granuloma 7.0
ovarian mixed germ cell tumor 7.0
Malignant Brenner tumor 7.0
clear cell carcinoma 7.0
stage IV pancreatic cancer 6.9
vaginal cancer 6.9
Ovarian metastasis 6.8
Intraepithelial Neoplasia 6.8
Splenic lymphoma 6.8
more...
Symptom
increased abdominal size 9.3
Sister Mary Joseph's nodule 6.2
intermenstrual pain 5.5
reproductive problem 5.0
menopausal symptoms 4.7
abdominal fullness 4.5
swollen leg 4.3
nipple pain 4.3
nipple pain 4.3
bloating 4.0
nausea and vomiting 3.8
Lhermitte's sign 3.8
peri-menopausal 3.7
pelvic pain 3.7
peau d'orange 3.6
Scratch 3.5
blemishes 3.5
hot flashes 3.3
hot flushes 3.2
vestibulitis 3.1
generalized rash 3.0
nausea 2.8
decreased appetite 2.8
Lower urinary tract symptoms 2.6
asthenia 2.6
vomiting 2.6
mastalgia 2.6
irregular bleeding 2.6
Gastrointestinal symptoms 2.5
disturbed balance 2.3
tenesmus 2.2
physical symptom 2.2
abdominal discomfort 2.2
abdominal pain 2.2
chills 1.9
dysarthria 1.8
cachexia 1.7
paresthesia 1.7
anorexia 1.6
myalgia 1.6
fatigue 1.5
night sweats 1.5
consciousness disturbance 1.5
belching 1.4
cerebellar ataxia 1.3
oliguria 1.3
HSA 1.2
constipation 1.1
acute abdomen 1.1
Decreased activity 1.1
ataxic gait 1.0
arthralgia 1.0
Ill 1.0
hopelessness 1.0
pleuritic chest pain 0.9
overweight 0.9
tonic-clonic seizure 0.8
leg edema 0.7
diarrhea 0.7
lethargy 0.7
dyspnea 0.6
shortness of breath 0.6
chronic back pain 0.6
chest tightness 0.6
bone pain 0.5
starvation 0.5
ataxia 0.5
flushing 0.5
hemiplegia 0.5
despair 0.5
renal colic 0.5
insomnia 0.5
discomfort 0.4
myoclonus 0.4
sneezing 0.2
acute abdominal pain 0.2
erythema 0.2
dry skin 0.2
eds 0.1
urinary frequency 0.0
more...
Drug
Flufenamic Acid 10.1
Enloplatin 10.1
Fucitol 10.1
Aqupla 10.1
Oregovomab 10.0
OncoScint CR/OV 9.1
Tiazofurine 8.6
IFEX 8.6
Lysophosphatidylglycerol 8.6
Rubitecan 8.1
Trabectedin 7.9
OncoScint 7.8
Topotecan hydrochloride 7.8
Sobuzoxane 7.6
Paraplatin 7.4
Ranimustine 7.3
Sizofiran 7.2
Irofulven 7.2
Buserelin acetate 7.0
18DG 7.0
Triptorelin 6.9
Mapatumumab 6.8
Epothilone B 6.6
Torecan 6.6
Torecan 6.6
Taxol 6.5
Semaxanib 6.4
Ethyol 5.9
Blenoxane 5.8
Mifepriston 5.8
Edatrexate 5.8
Cefuzonam 5.8
Ortho Tri-Cyclen 5.8
Cetrorelix 5.7
Pertuzumab 5.7
Aromasin 5.7
Tanespimycin 5.6
Bevacizumab 5.6
Taxotere 5.5
Navoban 5.5
Navoban 5.5
Diamminedichloroplatinum 5.4
Amifostine 5.4
Lenograstim 5.4
Satraplatin 5.4
Tora 5.4
Lisofylline 5.4
Sodium phenylbutyrate 5.3
Cremophor EL 5.3
Docetaxel 5.3
Ontak 5.2
Ontak 5.2
TTC 5.2
Talc 5.2
Isoxicam 5.2
Teniposide 5.2
Lubeluzole 5.1
Sodium thiosulfate 5.1
Marimastat 5.0
Lonafarnib 4.9
CPT-11 4.9
Oxaliplatin 4.9
Glucose-6-Phosphate 4.9
Doxifluridine 4.9
Naftopidil 4.9
Alimta 4.8
Hoelen 4.8
MT6 4.8
Auranofin 4.8
GEO 4.7
Verteporfin 4.7
Tarceva 4.7
Sandostatin LAR 4.7
Leukine 4.7
SISO 4.7
Zofran 4.7
Navelbine 4.6
ADR 4.6
Gemzar 4.6
Adriamycin 4.6
more...
Enzyme
matrix metalloproteinase-15 8.6
kallikrein 13 7.8
kallikrein 10 7.3
neurosin 6.7
neuropsin 6.2
EC 5.3.99.2 6.1
KLK13 6.0
CYP39A1 6.0
hepsin 5.5
hepsin 5.5
STK11 5.5
PARP 5.5
ALDH 5.4
tubulin-tyrosine ligase 5.2
KLK7 5.2
neuropsin 5.1
MHCK 5.1
inositol polyphosphate 4-phosphatase 5.0
prostasin 4.9
stratum corneum chymotryptic enzyme 4.9
matriptase 4.8
deoxycytidine deaminase 4.7
STK4 4.7
GK2 4.7
lysophospholipase D 4.7
proprotein convertase 1 4.6
nicotinamide N-methyltransferase 4.6
methioninase 4.4
HK2 4.3
matriptase 4.3
MTD 4.2
spermidine/spermine N1-acetyltransferase 4.2
phosphoserine aminotransferase 4.2
DHAD 4.2
PFI 4.1
Lod 4.1
pregnancy-associated plasma protein-A 4.0
asparagine synthetase 4.0
nicotinic acid phosphoribosyltransferase 4.0
STK 3.9
tissue kallikrein 3.9
oxoglutarate dehydrogenase 3.8
alpha-N-acetylgalactosaminidase 3.8
HCS 3.8
cytosine deaminase 3.8
urokinase-type plasminogen activator 3.7
MDR 3.7
caspase-9 3.7
deoxycytidine kinase 3.7
matrix metalloproteinase 2 3.7
topoisomerase 3.6
polypeptide N-acetylgalactosaminyltransferase 3.6
CLK1 3.6
topoisomerase 3.6
cancer procoagulant 3.6
gastricsin 3.6
lactose synthetase 3.6
GalT 3.6
CPM 3.6
glucosylceramide synthase 3.6
NQO2 3.5
P-glycoprotein 3.5
phosphatidylinositol-4,5-bisphosphate 3-kinase 3.5
cysteine synthase 3.4
uridyltransferase 3.4
thioredoxin reductase 3.4
beta-1,4-galactosyltransferase 3.4
caspase-8 3.4
caspase-3 3.4
sialyltransferase 3.4
choline kinase 3.4
sialyltransferase 3.4
sialyltransferase 3.4
rhomboid protease 3.3
ERK 3.3
GalNAc-T 3.3
site-1 protease 3.3
MEK 3.3
folylpolyglutamate synthetase 3.3
phosphatidylinositol 3-kinase 3.3
more...
Compound
C7H14N2 10.1
9-ethyl-9H-purine 10.1
C7H14N2 10.1
C7H14N2 10.1
C7H14N2 10.1
N-Acetylneuraminic acid 9-phosphate 10.1
C7H14N2 10.1
Strebloside 10.1
C7H14N2 10.1
C7H14N2 10.1
C7H14N2 10.1
C7H14N2 10.1
Gentisyl alcohol 9.1
C21H19NO4S 9.1
4,5-dichloro-1H-imidazole 9.1
C7H14N2 9.1
AD-143 9.1
C21H19NO4S 9.1
C12H8O2 9.1
2,5-dimethyl-3-furoic acid 9.1
C7H14N2 9.1
C21H19NO4S 9.1
N-(1,3-thiazol-2-yl)acetamide 9.1
5-hydroxy-2-phenyl-4H-chromen-4-one 9.1
Dianon 8.8
C7H14N2 8.6
C7H14N2 8.6
Norlichexanthone 8.6
C21H19NO4S 8.6
1,4-dimethyl-9H-carbazole 8.6
EOC 8.4
2-bromo-3-methylpyridine 8.1
4'-Epiadriamycin 8.1
Protecton 8.1
2,3-diphenylacrylonitrile 8.1
2-bromo-3-methylpyridine 8.1
Phenesterin 8.1
Trilaurin 7.8
Vernodalin 7.8
1,3-Diphenylpropane 7.8
Vernodalin 7.8
Theasaponin 7.6
HAPP 7.6
C20H22N2O2 7.6
3-phenyl-1H-indole 7.6
Bullatacin 7.4
Topotecan 7.4
Gracillin 7.3
1,1,3,3-tetramethoxypropane 7.3
Dioxadet 7.3
DHAC 7.1
Bismuth subnitrate 7.1
Girinimbine 7.0
Resibufogenin 7.0
Antheraxanthin 7.0
Cucurbitacin D 7.0
Benzophenone-1 6.9
Topotecan 6.9
CBDCA 6.9
CBDCA 6.9
Lycurim 6.8
Protodioscin 6.8
Aspidin 6.8
rubicene 6.7
2-benzylpyridine 6.7
4-ethoxyphenol 6.7
Gedunin 6.7
Paclitaxel 6.6
Epothilone B 6.6
vinyl pivalate 6.6
Torecan 6.6
2-benzylpyridine 6.6
Glucosylsphingosine 6.4
Carboquone 6.4
Carboquone 6.4
Carboquone 6.4
Carboquone 6.4
Picropodophyllin 6.3
Aloesin 6.3
Cotylenin A 6.3
more...