Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1140680 (
ovarian cancer
)
28,141
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
BRCA1
2531
Mol
1790
Sep
1773
BRCA2
1545
p53
1223
CA125
639
PARP
525
caspase-3
444
AKT
432
CA-125
372
cytokine
340
vascular endothelial growth factor
333
Bcl-2
328
PI3K
323
mTOR
297
E-cadherin
285
HER2
270
estrogen receptor
265
epidermal growth factor receptor
256
ERK
234
p21
233
MAPK
230
glycoprotein
225
VEGF
214
cage
212
DDP
209
CD8
204
NMR
188
catenin
188
She
187
erbB-2
184
PTEN
180
ERK1
175
CD44
170
matrix metalloproteinase
167
IL-6
164
collagen
164
cyclin D1
155
EGFR
155
p38
154
tyrosine kinase
153
histone
149
STAT3
147
tumor necrosis factor
142
ATM
141
UTR
140
poly(ADP-ribose) polymerase
139
ATP
137
P-glycoprotein
134
interferon
133
MRI
130
CD4
127
epidermal growth factor
127
MMP-9
126
vimentin
125
caspase-9
123
insulin
121
ubiquitin
121
survivin
120
chemokine
119
annexin V
118
IFN
118
progesterone receptor
118
proteasome
116
tumour suppressor
115
MMP-2
114
TNF
114
mucin
113
urokinase-type plasminogen activator
113
EGF
113
kit
112
MEK
112
IL-8
111
CEA
111
neu
110
cancer susceptibility
109
Pol
109
endoplasmic reticulum
108
JNK
107
PEG
106
more...
Disease
ovarian cancer
28141
cancer
16260
tumor
9624
epithelial ovarian cancer
4271
breast cancer
3583
carcinoma
1284
tumor growth
1174
metastases
1087
tumorigenesis
921
endometrial cancer
845
tumor progression
841
adenocarcinoma
789
carcinogenesis
749
cervical cancer
741
lung cancer
693
residual disease
630
melanoma
592
colorectal cancer
584
prostate cancer
538
Ovarian Cancer
489
colon cancer
407
fallopian tube
388
recurrent ovarian cancer
360
endometriosis
358
leukemia
353
gastric cancer
340
gynecologic cancer
326
pancreatic cancer
293
non-small cell lung cancer
257
carcinomatosis
244
neutropenia
242
DDP
235
thrombocytopenia
232
primary tumor
225
anemia
222
uterus
220
hepatocellular carcinoma
211
MCF
193
myelosuppression
191
metastatic ovarian cancer
185
malignant ascites
182
lymphoma
178
ovarian cysts
175
clear cell carcinoma
175
obesity
174
infertility
172
aggressiveness
170
ATM
167
Lynch syndrome
161
multiple myeloma
146
renal cell carcinoma
143
sarcoma
141
bladder cancer
139
squamous cell carcinoma
137
solid tumor
126
renal cancer
125
leukopenia
123
Hodgkin's disease
122
diabetes
119
glioblastoma
108
tumor angiogenesis
105
peritoneal cancer
105
metastatic breast cancer
104
liver cancer
104
glioma
103
mesothelioma
102
small cell lung cancer
102
uterine cancer
98
bowel obstruction
93
depression
92
hypertension
92
head and neck cancer
91
liver cancer
89
carcinoma of the breast
88
peripheral neuropathy
87
acute myeloid leukemia
86
GSH
80
testicular cancer
80
non-Hodgkin's lymphoma
78
B-cell lymphoma
77
more...
Symptom
vomiting
166
pain
147
nausea
145
fatigue
131
abdominal pain
125
nausea and vomiting
119
diarrhea
81
pelvic pain
45
overweight
44
headache
41
anesthesia
38
dyspnea
38
menopausal symptoms
37
anorexia
36
starvation
32
discomfort
29
weakness
25
bloating
23
Ill
20
constipation
20
ataxia
20
discomfort
18
myalgia
17
cachexia
16
seizures
15
paresthesia
14
asthenia
14
chills
14
arthralgia
13
insomnia
13
erythema
13
collapse
12
dysarthria
12
chest pain
11
respiratory distress
10
hot flushes
10
back pain
10
hot flashes
9
cough
9
cerebellar ataxia
8
stigma
8
analgesia
8
flushing
8
lethargy
8
abdominal fullness
8
exhaustion
8
shortness of breath
7
abdominal discomfort
7
decreased appetite
7
dizziness
7
acute abdomen
6
HSA
6
vertigo
6
Sister Mary Joseph's nodule
5
hemiplegia
5
low back pain
5
myoclonus
5
sleepiness
5
Scratch
4
agitation
4
oliguria
4
tinnitus
4
acidity
4
hypothermia
4
increased abdominal size
4
bone pain
4
hopelessness
4
Gastrointestinal symptoms
3
tremor
3
night sweats
3
numbness
3
peri-menopausal
2
tenesmus
2
neck pain
2
cancer pain
2
hemoptysis
2
sneezing
2
hunger
2
splenomegaly
2
pallor
2
more...
Drug
Taxol
252
Adriamycin
98
IL-2
81
lysine
79
Bevacizumab
76
CSF
71
IFN-gamma
67
ROS
64
TTC
62
Docetaxel
61
CTX
58
MAP
56
ROC
56
G-CSF
55
Monit
54
CPT-11
51
Herceptin
48
ADR
45
ADM
43
uPA
40
GEO
37
ABC
31
Trabectedin
30
vitamin E
29
lactose
26
EE2
25
ICI
25
Taxotere
25
Oxaliplatin
24
caffeine
22
Cremophor EL
22
CTX
21
Dermatol
21
ascorbate
20
CTX
20
Gel
19
HCG
19
Paraffin
19
Glutathione
17
Estrogens
17
Amifostine
14
NH3
14
ETS
14
Irinotecan
14
ENT
13
Cetuximab
13
Norplant
13
Leaf
12
CAM
12
Etoposide
12
BLM
11
MDS
9
Arsenic trioxide
9
VCR
9
NADH
9
Cetrorelix
9
p75
9
nitroglycerin
9
Asn
8
Diamminedichloroplatinum
8
DM1
8
Auranofin
8
IFN-beta
8
Bortezomib
8
Triptorelin
8
Dasatinib
8
TAT
8
Pemetrexed
8
G418
7
Depo-Provera
7
NVP
7
Gefitinib
7
Talc
7
VCR
7
Erlotinib
7
MRC
7
Paraplatin
7
CPM
7
Oregovomab
7
Imatinib
7
more...
Enzyme
ERK
855
mitogen-activated protein kinase
625
PARP
551
caspase-3
328
luciferase
316
focal adhesion kinase
247
protein kinase
217
MEK
157
P-glycoprotein
135
urokinase-type plasminogen activator
126
proteasome
119
topoisomerase
108
topoisomerase
99
phosphatidylinositol 3-kinase
95
caspase-9
86
ACS
76
protein kinase C
71
caspase-8
63
glutathione S-transferase
62
AMP-activated protein kinase
56
alkaline phosphatase
52
MDR
52
reverse transcriptase
51
APC
49
kallikrein
47
ATPase
46
lactate dehydrogenase
46
cdc2
46
trypsin
45
phosphoinositide 3-kinase
42
thymidine kinase
42
RNase
38
DNA methyltransferase
37
RNase
37
AMPK
35
RNA polymerase
35
peroxidase
34
MMP
34
ALDH
33
AMPK
32
aldehyde dehydrogenase
31
GSK
30
aldehyde dehydrogenase
30
aldehyde dehydrogenase
30
aldehyde dehydrogenase
30
aldehyde dehydrogenase
30
catalase
29
plasmin
28
DNA polymerase
28
thymidylate synthase
28
superoxide dismutase
26
matrix metalloproteinase 2
26
collagenase
26
endonuclease
25
prostate-specific antigen
25
phospholipase C
24
cathepsin D
24
thioredoxin reductase
23
IKK
23
cathepsin B
23
MAP
21
gamma-glutamyl transpeptidase
21
CYP3A4
21
STK11
19
calcineurin
18
alanine aminotransferase
18
glyceraldehyde-3-phosphate dehydrogenase
17
phospholipase A2
17
tissue kallikrein
16
firefly luciferase
15
sialyltransferase
14
sialyltransferase
14
sialyltransferase
14
PDK1
14
ribonuclease
13
beta-galactosidase
13
asparaginase
13
thrombin
13
matrix metalloproteinase 9
13
ribonuclease
13
more...
Compound
DNA
2962
Dec
1875
Clin
1647
DDP
496
MTT
485
oxygen
420
Paclitaxel
251
tyrosine
198
calcium
188
glucose
186
PEG
185
water
183
MDA
178
phosphate
177
CBDCA
147
CBDCA
147
PEG
144
serine
139
Pac
139
ATP
137
Adriamycin
132
bromide
126
arginine
118
ADP-ribose
118
TNF
114
lysine
112
cysteine
111
MEK
110
iodine
110
iron
108
sodium
104
ADR
103
acetate
101
ADP
100
methionine
92
GSH
92
GSH
92
galactose
86
hydrogen
79
ADP
77
ADP
76
ACS
76
Estrogen
76
ACS
76
Optimal
75
ethanol
75
threonine
75
vitamin D
73
Estrogen
72
NH2
69
TOF
68
creatinine
68
sulfate
66
PMA
61
Gemcitabine
61
Gemcitabine
61
Topotecan
60
copper
60
Topotecan
59
CAM
58
CTX
58
zinc
57
retinoic acid
56
nitric oxide
55
nitrogen
54
leucine
54
5-FU
53
Docetaxel
52
MDR
52
CPT-11
51
His
48
EOC
47
CAP
47
SDS
47
ASA
46
alanine
45
cAMP
45
CAP
44
dUTP
44
glutamine
43
more...