Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1140680 (ovarian cancer)
 28,141 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
BRCA1 2531
Mol 1790
Sep 1773
BRCA2 1545
p53 1223
CA125 639
PARP 525
caspase-3 444
AKT 432
CA-125 372
cytokine 340
vascular endothelial growth factor 333
Bcl-2 328
PI3K 323
mTOR 297
E-cadherin 285
HER2 270
estrogen receptor 265
epidermal growth factor receptor 256
ERK 234
p21 233
MAPK 230
glycoprotein 225
VEGF 214
cage 212
DDP 209
CD8 204
NMR 188
catenin 188
She 187
erbB-2 184
PTEN 180
ERK1 175
CD44 170
matrix metalloproteinase 167
collagen 164
IL-6 164
cyclin D1 155
EGFR 155
p38 154
tyrosine kinase 153
histone 149
STAT3 147
tumor necrosis factor 142
ATM 141
UTR 140
poly(ADP-ribose) polymerase 139
ATP 137
P-glycoprotein 134
interferon 133
MRI 130
CD4 127
epidermal growth factor 127
MMP-9 126
vimentin 125
caspase-9 123
insulin 121
ubiquitin 121
survivin 120
chemokine 119
IFN 118
annexin V 118
progesterone receptor 118
proteasome 116
tumour suppressor 115
TNF 114
MMP-2 114
urokinase-type plasminogen activator 113
EGF 113
mucin 113
MEK 112
kit 112
IL-8 111
CEA 111
neu 110
cancer susceptibility 109
Pol 109
endoplasmic reticulum 108
JNK 107
PEG 106
N-cadherin 104
fibronectin 103
PALB2 102
Brca1 101
cyclin E 101
HE4 99
folate receptor 97
phosphatidylinositol 3-kinase 95
CD133 95
topoisomerase I 93
histone deacetylase 93
RAD51 93
poly (ADP-ribose) polymerase 92
Ki-67 92
KRAS 91
PD-L1 89
carcinoembryonic antigen 88
p27 86
cytochrome c 85
mesothelin 84
extracellular signal-regulated kinase 83
BRCA1 protein 82
MUC1 82
IL-10 82
PD-1 81
p16 81
caspase-8 81
GSH 80
IL-2 80
MDR1 79
Poly 79
CHEK2 78
fused 77
polypeptide 77
PIK3CA 77
c-Myc 76
ADP 76
ACS 76
mutant p53 75
RAD51C 71
MMP9 71
non-Hodgkin's lymphoma 70
proto-oncogene 69
BARD1 69
TOF 68
IFN-gamma 68
FDG 68
HLA 68
macrophage colony-stimulating factor 68
CCK 67
granulocyte colony-stimulating factor 66
MLH1 66
Rho 66
EGF receptor 66
interleukin-6 65
LHRH 65
MSH2 65
ROS 64
c-Jun 64
nodal 64
osteosarcoma 62
c-myc 62
interleukin-2 62
CXCR4 61
cyclin 61
BRIP1 61
ras 60
lectin 60
MUC16 60
androgen receptor 60
aromatase 60
CD24 59
focal adhesion kinase 59
Fas 59
phosphatase 59
FSH 59
receptor tyrosine kinase 59
BRAF 58
albumin 58
LC3 58
more...
Disease
ovarian cancer 28141
cancer 16260
tumor 9624
epithelial ovarian cancer 4271
breast cancer 3583
carcinoma 1284
tumor growth 1174
metastases 1087
tumorigenesis 921
endometrial cancer 845
tumor progression 841
adenocarcinoma 789
carcinogenesis 749
cervical cancer 741
lung cancer 693
residual disease 630
melanoma 592
colorectal cancer 584
prostate cancer 538
Ovarian Cancer 489
colon cancer 407
fallopian tube 388
recurrent ovarian cancer 360
endometriosis 358
leukemia 353
gastric cancer 340
gynecologic cancer 326
pancreatic cancer 293
non-small cell lung cancer 257
carcinomatosis 244
neutropenia 242
DDP 235
thrombocytopenia 232
primary tumor 225
anemia 222
uterus 220
hepatocellular carcinoma 211
MCF 193
myelosuppression 191
metastatic ovarian cancer 185
malignant ascites 182
lymphoma 178
clear cell carcinoma 175
ovarian cysts 175
obesity 174
infertility 172
aggressiveness 170
ATM 167
Lynch syndrome 161
multiple myeloma 146
renal cell carcinoma 143
sarcoma 141
bladder cancer 139
squamous cell carcinoma 137
solid tumor 126
renal cancer 125
leukopenia 123
Hodgkin's disease 122
diabetes 119
glioblastoma 108
peritoneal cancer 105
tumor angiogenesis 105
liver cancer 104
metastatic breast cancer 104
glioma 103
mesothelioma 102
small cell lung cancer 102
uterine cancer 98
bowel obstruction 93
depression 92
hypertension 92
head and neck cancer 91
liver cancer 89
carcinoma of the breast 88
peripheral neuropathy 87
acute myeloid leukemia 86
testicular cancer 80
GSH 80
non-Hodgkin's lymphoma 78
B-cell lymphoma 77
SCID 77
Fanconi 77
neuroblastoma 76
epididymis 75
tumor initiation 75
pelvic inflammatory disease 73
APC 73
osteosarcoma 71
lung carcinoma 71
ovarian neoplasm 69
retinoblastoma 69
peritonitis 67
polyposis 66
measurable disease 66
osteoporosis 64
minimal residual disease 64
adenoma 62
thyroid cancer 62
cardiovascular disease 60
bilateral breast cancer 59
benign tumor 58
epithelial tumor 58
esophageal cancer 56
familial cancer 56
Best 56
liver metastases 54
esophageal cancer 53
WT1 52
neuropathy 52
vulvar cancer 52
tuberculosis 52
ectopic pregnancy 52
fallopian tube cancer 51
stroke 51
Poland 50
stromal tumors 49
AS1 49
uterine cervix 48
Li-Fraumeni syndrome 47
abortion 47
skin cancer 46
familial adenomatous polyposis 46
polycystic ovary syndrome 46
aggression 46
cancer recurrence 45
SDS 45
Blocking 44
mucinous carcinoma 44
EMT 44
CAP 44
West 44
ovarian serous cystadenocarcinoma 44
rectal cancer 43
stage III ovarian cancer 43
vagina 43
teratoma 42
psychological distress 42
choriocarcinoma 41
neoplastic transformation 41
HIV 40
herpes simplex 40
ovarian cancer stage 39
tumor vasculature 38
brain metastases 38
myelodysplastic syndrome 37
Fallopian tube 37
hematologic malignancies 37
HRA 37
Ovary 36
Peutz-Jeghers syndrome 36
rash 36
acute lymphoblastic leukemia 36
invasive cancer 36
rheumatoid arthritis 36
myocardial infarction 35
stomatitis 35
gastrointestinal cancer 35
dysplasia 34
HCG 34
cirrhosis 34
more...
Symptom
vomiting 166
pain 147
nausea 145
fatigue 131
abdominal pain 125
nausea and vomiting 119
diarrhea 81
pelvic pain 45
overweight 44
headache 41
anesthesia 38
dyspnea 38
menopausal symptoms 37
anorexia 36
starvation 32
discomfort 29
weakness 25
bloating 23
constipation 20
ataxia 20
Ill 20
discomfort 18
myalgia 17
cachexia 16
seizures 15
asthenia 14
paresthesia 14
chills 14
insomnia 13
arthralgia 13
erythema 13
collapse 12
dysarthria 12
chest pain 11
respiratory distress 10
back pain 10
hot flushes 10
cough 9
hot flashes 9
cerebellar ataxia 8
flushing 8
abdominal fullness 8
analgesia 8
lethargy 8
stigma 8
exhaustion 8
abdominal discomfort 7
shortness of breath 7
dizziness 7
decreased appetite 7
acute abdomen 6
HSA 6
vertigo 6
hemiplegia 5
sleepiness 5
Sister Mary Joseph's nodule 5
myoclonus 5
low back pain 5
increased abdominal size 4
acidity 4
tinnitus 4
hopelessness 4
Scratch 4
agitation 4
oliguria 4
bone pain 4
hypothermia 4
Gastrointestinal symptoms 3
tremor 3
night sweats 3
numbness 3
neck pain 2
tenesmus 2
colic 2
epigastric pain 2
splenomegaly 2
pallor 2
paresis 2
syncope 2
despair 2
tonic-clonic seizure 2
irregular bleeding 2
memory loss 2
peri-menopausal 2
consciousness disturbance 2
acute abdominal pain 2
hemoptysis 2
masculinization 2
cancer pain 2
mastalgia 2
hunger 2
distraction 2
sneezing 2
ENT 2
dry skin 1
leg pain 1
physical symptom 1
skin irritation 1
pleuritic chest pain 1
apathy 1
chronic back pain 1
intermenstrual pain 1
Lower urinary tract symptoms 1
renal colic 1
reproductive problem 1
ataxic gait 1
nipple pain 1
vestibulitis 1
Decreased activity 1
swollen leg 1
ophthalmoplegia 1
exertional dyspnea 1
chronic cough 1
angina 1
nipple pain 1
dystonia 1
dysuria 1
belching 1
blurred vision 1
nasal congestion 1
eds 1
tachypnea 1
fasciculation 1
fever of unknown origin 1
Mills 1
disturbed balance 1
knee pain 1
flank pain 1
tingling 1
dry eye 1
generalized rash 1
hyperoxia 1
hepatosplenomegaly 1
Lhermitte's sign 1
chest tightness 1
hoarseness 1
peau d'orange 1
shoulder pain 1
leg edema 1
functional recovery 1
blemishes 1
hypoproteinemia 1
thinning 1
urinary frequency 1
Drug
Taxol 252
Adriamycin 98
IL-2 81
lysine 79
Bevacizumab 76
CSF 71
IFN-gamma 67
ROS 64
TTC 62
Docetaxel 61
CTX 58
MAP 56
ROC 56
G-CSF 55
Monit 54
CPT-11 51
Herceptin 48
ADR 45
ADM 43
uPA 40
GEO 37
ABC 31
Trabectedin 30
vitamin E 29
lactose 26
Taxotere 25
EE2 25
ICI 25
Oxaliplatin 24
Cremophor EL 22
caffeine 22
Dermatol 21
CTX 21
ascorbate 20
CTX 20
HCG 19
Gel 19
Paraffin 19
Estrogens 17
Glutathione 17
ETS 14
NH3 14
Irinotecan 14
Amifostine 14
ENT 13
Norplant 13
Cetuximab 13
CAM 12
Etoposide 12
Leaf 12
BLM 11
Cetrorelix 9
Arsenic trioxide 9
MDS 9
p75 9
NADH 9
nitroglycerin 9
VCR 9
IFN-beta 8
Dasatinib 8
Bortezomib 8
Asn 8
TAT 8
Pemetrexed 8
Auranofin 8
Triptorelin 8
DM1 8
Diamminedichloroplatinum 8
Oregovomab 7
Erlotinib 7
Talc 7
Orphan 7
CPM 7
MRC 7
NVP 7
Imatinib 7
Depo-Provera 7
Filgrastim 7
Gefitinib 7
G418 7
VCR 7
Paraplatin 7
Ethyol 6
CCL 6
CoCl2 6
Sorafenib 6
Pertuzumab 6
Mutagen 6
CoCl2 6
Levonorgestrel 6
Activin 6
Vinorelbine 6
Emodin 5
Gleevec 5
Verteporfin 5
Emodin 5
ampicillin 5
Albumin 5
PMEA 5
CTC 5
Vitamin A 5
DNase I 5
CTC 5
Filgrastim 5
Tarceva 5
Raloxifene 5
MOF 5
Lactose 5
Irofulven 4
Indomethacin 4
Epigallocatechin 4
Urokinase 4
Heme 4
Galactose 4
Norplant 4
Artesunate 4
Parkin 4
Parkin 4
citric acid 4
Navelbine 4
Cardiovasc 4
RFP 4
ETA 4
Spectrum 4
Lupron 4
NOV 4
Gemzar 4
Luteinizing 3
Fluorescein 3
FAD 3
Everolimus 3
ZnO 3
Hypaque 3
Doxycycline 3
Fulvestrant 3
DEX 3
Nitric Oxide 3
Clomiphene citrate 3
Zoladex 3
Premarin 3
Lactase 3
Teniposide 3
Hypaque 3
Tocopherol 3
Vitamin E 3
Sodium thiosulfate 3
Gelatin 3
PFT 3
Propofol 3
AMC 3
KGF 3
ALA 3
Encore 3
Thioridazine 3
Sizofiran 3
Spectrum 3
Orlistat 3
Fluorescein 3
Myricetin 3
MDM 3
more...
Enzyme
ERK 855
mitogen-activated protein kinase 625
PARP 551
caspase-3 328
luciferase 316
focal adhesion kinase 247
protein kinase 217
MEK 157
P-glycoprotein 135
urokinase-type plasminogen activator 126
proteasome 119
topoisomerase 108
topoisomerase 99
phosphatidylinositol 3-kinase 95
caspase-9 86
ACS 76
protein kinase C 71
caspase-8 63
glutathione S-transferase 62
AMP-activated protein kinase 56
alkaline phosphatase 52
MDR 52
reverse transcriptase 51
APC 49
kallikrein 47
ATPase 46
cdc2 46
lactate dehydrogenase 46
trypsin 45
phosphoinositide 3-kinase 42
thymidine kinase 42
RNase 38
RNase 37
DNA methyltransferase 37
AMPK 35
RNA polymerase 35
MMP 34
peroxidase 34
ALDH 33
AMPK 32
aldehyde dehydrogenase 31
aldehyde dehydrogenase 30
aldehyde dehydrogenase 30
aldehyde dehydrogenase 30
aldehyde dehydrogenase 30
GSK 30
catalase 29
plasmin 28
thymidylate synthase 28
DNA polymerase 28
superoxide dismutase 26
matrix metalloproteinase 2 26
collagenase 26
prostate-specific antigen 25
endonuclease 25
phospholipase C 24
cathepsin D 24
IKK 23
cathepsin B 23
thioredoxin reductase 23
CYP3A4 21
MAP 21
gamma-glutamyl transpeptidase 21
STK11 19
alanine aminotransferase 18
calcineurin 18
phospholipase A2 17
glyceraldehyde-3-phosphate dehydrogenase 17
tissue kallikrein 16
firefly luciferase 15
sialyltransferase 14
PDK1 14
sialyltransferase 14
sialyltransferase 14
ribonuclease 13
ribonuclease 13
matrix metalloproteinase 9 13
thrombin 13
beta-galactosidase 13
asparaginase 13
demethylase 12
indoleamine 2,3-dioxygenase 12
glutaminase 12
transcriptase 11
ceruloplasmin 11
ribonucleotide reductase 11
dihydrofolate reductase 11
glutathione peroxidase 11
lipase 11
CD10 10
beta-glucuronidase 10
HK2 10
granzyme B 10
MTD 10
ribonucleotide reductase 10
histone acetyltransferase 10
ricin 10
MEKK1 10
neuropsin 10
complex I 10
pyruvate kinase 9
CPT 9
neuraminidase 9
matriptase 9
cytosine deaminase 9
CPT 9
NQO1 9
NADPH oxidase 9
CPT 9
tissue plasminogen activator 9
matriptase 9
aspartate aminotransferase 9
hyaluronidase 8
glutathione reductase 8
renin 8
deoxycytidine kinase 8
NADPH oxidase 8
caspase-1 8
arginase 8
kinesin 8
TAT 8
gamma-glutamylcysteine synthetase 8
polo-like kinase 1 8
creatine kinase 7
MMP-3 7
thymidine phosphorylase 7
transglutaminase 7
CPM 7
GRK2 7
PTPase 7
phospholipase D 7
asparagine synthetase 7
PAM 7
NOS 7
pyruvate dehydrogenase 6
methylenetetrahydrofolate reductase 6
carboxylesterase 6
glyceraldehyde-3-phosphate dehydrogenase 6
histone demethylase 6
furin 6
tyrosinase 6
cysteine synthase 6
adenosine deaminase 6
adenosine deaminase 6
farnesyltransferase 6
methylenetetrahydrofolate reductase 6
DNA ligase 6
hyaluronidase 6
farnesyltransferase 6
DNA ligase 6
glyceraldehyde-3-phosphate dehydrogenase 6
MIP 6
KLK7 6
hexokinase 6
pyruvate dehydrogenase 6
glyceraldehyde-3-phosphate dehydrogenase 6
protein phosphatase 2A 6
hepsin 6
glyceraldehyde-3-phosphate dehydrogenase 6
pyruvate dehydrogenase 6
more...
Compound
DNA 2962
Dec 1875
Clin 1647
DDP 496
MTT 485
oxygen 420
Paclitaxel 251
tyrosine 198
calcium 188
glucose 186
PEG 185
water 183
MDA 178
phosphate 177
CBDCA 147
CBDCA 147
PEG 144
serine 139
Pac 139
ATP 137
Adriamycin 132
bromide 126
arginine 118
ADP-ribose 118
TNF 114
lysine 112
cysteine 111
MEK 110
iodine 110
iron 108
sodium 104
ADR 103
acetate 101
ADP 100
GSH 92
GSH 92
methionine 92
galactose 86
hydrogen 79
ADP 77
Estrogen 76
ACS 76
ADP 76
ACS 76
threonine 75
ethanol 75
Optimal 75
vitamin D 73
Estrogen 72
NH2 69
creatinine 68
TOF 68
sulfate 66
Gemcitabine 61
Gemcitabine 61
PMA 61
copper 60
Topotecan 60
Topotecan 59
CTX 58
CAM 58
zinc 57
retinoic acid 56
nitric oxide 55
nitrogen 54
leucine 54
5-FU 53
MDR 52
Docetaxel 52
CPT-11 51
His 48
SDS 47
EOC 47
CAP 47
ASA 46
cAMP 45
alanine 45
CAP 44
dUTP 44
Metformin 43
Metformin 43
glutamine 43
salt 41
boron 40
VP-16 40
pyridine 38
GTP 38
hyaluronic acid 37
MAP 36
TPA 35
TPA 35
proline 35
Asp 35
Insulin 35
silver 34
urea 33
PAC 33
Gly 33
NAD 32
TNM 32
Tamoxifen 32
Vimentin 32
MTS 31
N-acetylcysteine 31
anthracene 31
SN-38 31
Phe 31
Progesterone 30
Tamoxifen 30
TEM 29
GlcNAc 28
AMP 28
PGA 28
DMSO 27
tryptophan 26
ICI 26
selenium 25
pyrimidine 25
pyrimidine 25
valine 25
tryptophan 25
methanol 24
tryptophan 24
NAD 24
tryptophan 24
ammonium 24
Resveratrol 23
THP 23
THP 23
Ile 23
ammonia 23
SCC 22
potassium 22
caffeine 22
Hoechst 33342 21
Curcumin 21
6-12 21
fluorine 21
glutamate 21
L-PAM 21
Histone 20
uridine 20
silicon 20
L-PAM 20
BLM 20
GMP 20
ethyl acetate 19
MMC 19
nicotinamide 19
formaldehyde 19
Ifosfamide 19
acridine 19
Estradiol 18
PGE2 18
Mitoxantrone 18
benzene 18
XTT 18
Kallikrein 17
Mitoxantrone 17
DBA 17
more...