Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0948265 (metabolic syndrome)
 24,271 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
OR4F6 10.4
CD97 molecule 10.4
small nuclear ribonucleoprotein polypeptide B 10.4
ZNF771 10.4
FLJ20584 10.4
MARP3 10.4
C2orf47 10.4
Nucleoside diphosphate kinase 7 10.4
Lipin 3 10.4
HERPUD2 10.4
ZBTB42 protein 10.4
KIAA0754 10.4
OR5R1 10.4
LOC100129150 10.4
Yip1 domain family, member 6 10.4
chromosome 10 open reading frame 104 10.4
LIM domain only 3 9.8
ZFS-1 9.4
Transmembrane protein 126B 9.4
CSRNP3 9.4
NADH dehydrogenase flavoprotein 1 9.4
C2orf16 9.4
ATP5S 9.4
GFOD2 9.4
Zinc finger protein 263 9.4
SNRPC 9.4
heterogeneous nuclear ribonucleoprotein U-like 2 9.4
OR13G1 9.4
FAM174A 9.1
makorin ring finger protein 1 8.8
Zfp69 8.8
G protein-coupled inward rectifier potassium channel 8.8
ZNF860 8.8
CTBP1 protein 8.8
Meteorin-like protein 8.8
CORS-26 8.8
alpha-1A-adrenergic receptor 8.8
PER3 protein 8.8
TSRC1 8.8
ZNF804B 8.8
CWF19L1 8.8
ZBTB42 8.8
HSFA 8.6
5-hydroxytryptamine (serotonin) receptor 2C 8.6
HF12 8.4
ANKRD9 8.4
STRA13 protein 8.4
AD031 8.4
INSIG-2 8.4
FAM110A 8.4
cAMP responsive element binding protein 3-like 3 8.4
TMEM56 8.4
NUCKS protein 8.4
OR52E4 8.4
ERLIN1 8.2
ORP10 8.2
STE20/SPS1-related proline-alanine-rich protein kinase 8.2
Ras homolog gene family, member C 8.0
SQRDL 8.0
hSRBC 8.0
FNTB 8.0
ubiquinol-cytochrome c reductase binding protein 8.0
GPR82 8.0
TRPC4AP 8.0
SHR4 8.0
PJA2 8.0
UXS1 8.0
SLC35D3 8.0
VI-3 8.0
fasting-induced protein 8.0
NPC1L1 protein 7.9
GSTA4 protein 7.8
NWD1 7.8
SPTBN5 7.8
YIPF6 7.8
FETUB 7.8
SLC2A6 7.8
CROCC 7.8
Upstream transcription factor 1 7.8
aspartate aminotransferase 1 7.8
more...
Disease
metabolic syndrome 10.4
Non STEMI 10.4
FPLD3 9.7
Insulin resistance in diabetes 9.4
Other cardiovascular disease 9.4
Allergic diarrhea 9.4
abdominal obesity 9.0
Postmenopausal symptoms 8.8
Android obesity 8.8
Diabetic diarrhea 8.8
Chronic skin disease 8.8
Premature pubarche 8.5
Nonalcoholic fatty liver 8.4
protein metabolism disorder 8.4
Precocious pubarche 8.2
FPLD2 8.2
Coronary atheroma 8.0
Other endocrine disorders 8.0
Acute mania 8.0
Hypertrophic obesity 8.0
Hypotriglyceridemia 8.0
dyslipidemia 8.0
metabolic syndrome X 7.8
Premature adrenarche 7.8
Clinical diabetic nephropathy 7.8
Depressive episode 7.8
FH II 7.8
Uric acid nephrolithiasis 7.7
Non-dipping 7.7
alcoholic fatty liver 7.6
Clitoris 7.6
Other sleep disorders 7.6
hyperfructosemia 7.6
purine metabolism disorder 7.6
Chronic telogen effluvium 7.6
Familial partial lipodystrophy 7.5
syndrome X 7.4
Androgen deficiency 7.4
Adult celiac disease 7.4
pancreatic islet hyperplasia 7.4
Cryptogenic cirrhosis 7.4
fatty liver 7.2
Hepatic glycogenosis 7.2
overnutrition 7.1
prediabetes 7.1
alcohol flush reaction 7.0
Pyoderma vegetans 7.0
Generalized obesity 7.0
Intraepithelial Neoplasia 7.0
glucose intolerance 7.0
glycopenia 7.0
hyperuricemia 6.9
MONA 6.9
Chronic liver disease and cirrhosis 6.9
Surgical menopause 6.9
Physical deconditioning 6.8
Secondary adrenal insufficiency 6.8
obesity 6.7
Male hypogonadism 6.7
Familial combined hyperlipidemia 6.7
EDMD2 6.7
Primary hypogonadism 6.7
Other dermatoses 6.7
Hypertension complicated 6.7
type 2 diabetes 6.6
Nodular glomerulosclerosis 6.6
hyperinsulinemia 6.6
atherosclerotic cardiovascular disease 6.6
Aromatase deficiency 6.6
Phrynoderma 6.6
Combined hyperlipidemia 6.6
End stage liver disease 6.6
Impaired insulin secretion 6.5
NFLD 6.5
NIDDM1 6.5
lipodystrophy 6.4
hyperandrogenism 6.4
cardiovascular risk factor 6.4
Overweight and obesity 6.4
Hidradenitis suppurativa 6.4
more...
Symptom
Metabolic symptoms 10.4
Appetite suppression 7.0
Musculoskeletal discomfort 6.6
SYMPTOMS 6.5
hypnagogic hallucination 6.3
Male sexual dysfunction 6.1
overweight 5.9
unable to sleep 5.8
Tissue sensitivity 5.2
peri-menopausal 4.9
Referred pain 4.6
female puberty 4.4
Murphy's sign 4.4
Lower urinary tract symptoms 4.4
Skin symptoms 4.2
leg cramps 4.2
corpulence 4.1
hot flashes 4.1
cachexia 4.0
male puberty 3.9
autodigestion 3.6
Exercise intolerance 3.5
snoring 3.4
menopausal symptoms 3.4
Catch 3.4
loss of equilibrium 3.2
nocturnal polyuria 3.1
Depressive symptoms 3.1
voice change 3.1
hunger 3.1
Severe pain 3.0
hepatomegaly 3.0
pachyonychia 2.8
ketonuria 2.8
hot flushes 2.7
hand pain 2.7
Cushingoid 2.6
abnormal breathing 2.6
polydipsia 2.6
Cushingoid 2.5
ACHE 2.5
Multimorbidity 2.5
hypersomnia 2.3
male subfertility 2.3
eds 2.3
sleepiness 2.3
Decreased activity 2.3
lassitude 2.2
masculinization 2.2
No adverse effect 2.0
Poor sleep 1.8
angina 1.8
exertional angina 1.8
polyuria 1.8
Scratch 1.7
night sweats 1.7
insomnia 1.7
enuresis 1.7
memory loss 1.5
starvation 1.5
anorexia 1.4
acute stress 1.4
microbial colonization 1.3
fatigue 1.3
swollen joints 1.3
exhaustion 1.3
personality change 1.2
constipation 1.2
abdominal discomfort 1.2
decreased appetite 1.2
dental pain 1.1
flushing 1.0
atypical chest pain 1.0
chronic constipation 1.0
asynergy 1.0
Sedation 1.0
limb pain 1.0
right upper quadrant pain 0.9
CSR 0.9
physical appearance 0.8
more...
Drug
Cynt 10.4
Eucommia bark 10.4
Loquat leaf 9.4
Radicut 8.0
Capsicum oleoresin 7.0
Rimonabant 7.0
Micardis 6.9
Creosote 6.7
Fructose 6.5
Tesaglitazar 6.5
Candoxatril 6.4
Colestimide 6.4
Muraglitazar 6.3
Actos 6.1
Bezafibrate 6.1
Ramelteon 6.0
Olmesartan 6.0
Metreleptin 6.0
Omacor 5.9
Ezetimibe 5.8
Avandia 5.8
Arachidonic Acid 5.7
Rosuvastatin 5.7
NAH 5.7
Colesevelam 5.6
Orlistat 5.6
Febuxostat 5.5
Adenosine Monophosphate 5.5
Candoxatril 5.5
Tryptophane 5.4
K201 5.3
Nebivolol 5.3
niacin 5.3
Lescol 5.2
Torcetrapib 5.1
Monosodium glutamate 5.0
Lescol 5.0
Voglibose 5.0
Rosiglitazone 4.9
fluphenazine dihydrochloride 4.9
Alfacalcidol 4.8
Regadenoson 4.8
Lumiracoxib 4.7
Solon 4.7
Olive oil 4.7
Potassium citrate 4.7
Aliskiren 4.7
Valsartan 4.6
Enalapril maleate 4.6
Humalog 4.6
Benzylamine 4.5
Red ginseng 4.5
Tibolone 4.4
Rize 4.4
Rosuvastatin calcium 4.4
ADM 4.3
Alfuzosin 4.3
Sesame oil 4.3
Pramlintide 4.3
Tipifarnib 4.2
Pyridoxamine 4.2
Clozaril 4.1
Hakka 4.1
Pegvisomant 4.0
Ramipril 3.9
Compound 19 3.9
Insulin detemir 3.9
Simvastatin 3.8
AHF 3.8
AMK 3.8
Glybenclamide 3.7
Malonaldehyde 3.7
Clove 3.7
NOV 3.6
Troglitazone 3.6
Sevelamer 3.6
Gemfibrozil 3.6
Sesamol 3.5
Dutasteride 3.5
TPV 3.5
more...
Enzyme
phosphoglucokinase 8.0
ketohexokinase 7.6
carnitine O-octanoyltransferase 7.0
BCKDH 6.8
retinol saturase 6.7
11beta-hydroxysteroid dehydrogenase 6.5
acetate CoA-transferase 6.1
20beta-hydroxysteroid dehydrogenase 6.0
fructokinase 5.8
alkylglycerol monooxygenase 5.8
calpain 10 5.4
SOAT 5.3
selenocysteine lyase 5.2
LPL 5.1
FADS 5.1
AMP-activated kinase 5.1
choline dehydrogenase 5.1
acetoacetyl-CoA synthetase 5.0
chondroitin 6-sulfotransferase 5.0
long-chain acyl-coenzyme A dehydrogenase 5.0
AMP-activated protein kinase 4.9
SRR 4.9
CYP8B1 4.9
1-acylglycerol-3-phosphate O-acyltransferase 4.7
acetyl-CoA carboxylase 4.7
bile salt hydrolase 4.7
AMPK 4.7
glycine amidinotransferase 4.6
betaine-homocysteine methyltransferase 4.6
CYP7A1 4.6
GPH 4.6
serum carnosinase 4.5
dimethylarginine dimethylaminohydrolase 4.4
carnosinase 4.4
Delta6-desaturase 4.4
lipoprotein lipase 4.2
5beta-reductase 4.2
paraoxonase 4.1
arachidonate 5-lipoxygenase 4.1
BAT 4.1
3-hydroxy-3-methylglutaryl coenzyme A reductase 4.1
myo-inositol oxygenase 4.1
endoglycoceramidase 4.0
prostaglandin F synthase 4.0
retinyl ester hydrolase 4.0
AST 4.0
hormone-sensitive lipase 4.0
heparitinase I 4.0
carnitine acetyltransferase 4.0
alanine aminotransferase 4.0
fatty acid elongase 3.9
matrix metalloproteinase 14 3.9
diacylglycerol acyltransferase 3.9
pyruvate dehydrogenase phosphatase 3.9
uricase 3.8
angiotensin-converting enzyme 2 3.8
isovaleryl-CoA dehydrogenase 3.8
nicotinamide N-methyltransferase 3.8
flavonoid 3'-hydroxylase 3.8
neurolysin 3.8
phosphoglycolate phosphatase 3.8
paraoxonase 3.8
branched-chain alpha-keto acid dehydrogenase 3.8
phosphatidylinositol-4,5-bisphosphate 3-kinase 3.7
monoacylglycerol acyltransferase 3.7
AMPK 3.7
renin 3.7
glucokinase 3.6
site-1 protease 3.6
xanthine dehydrogenase 3.5
phosphoenolpyruvate carboxykinase 3.5
biotin carboxylase 3.5
ribokinase 3.5
gamma-glutamyl transpeptidase 3.5
soluble epoxide hydrolase 3.5
sphingomyelin synthase 3.5
superoxide reductase 3.4
aspartate aminotransferase 3.4
NADPH oxidase 3.4
nicotinamide phosphoribosyltransferase 3.4
more...
Compound
Triuret 8.4
C6H12N2O 8.0
hexaric acid 7.8
Vitamin U 7.8
hexaric acid 7.8
hexaric acid 7.8
C3H7NO2 7.6
o-Coumaric acid 7.6
Aloesin 7.6
hexaric acid 7.4
9(S)-HODE 7.2
1-phenylethanone 7.0
1-phenylethanone 7.0
1-phenylethanone 7.0
1-phenylethanone 7.0
Epicoprostanol 6.9
cholestan-3-ol 6.9
1-phenylethanone 6.9
Perezone 6.9
Moxonidine 6.8
1-phenylethanone 6.7
hexaric acid 6.7
Fagomine 6.7
Cholesterol 6.6
Sterculic acid 6.6
p-Synephrine 6.5
Fructose 6.4
Fenofibrate 6.3
Norathyriol 6.3
N(1)-methyl-2-pyridone-5-carboxamide 6.3
Ruscogenin 6.2
Potassium oxonate 6.2
1-Pyrroline 6.0
Pioglitazone 6.0
Telmisartan 6.0
Stearoyl-CoA 6.0
Sarsasapogenin 6.0
MEDA 6.0
3,3-dimethyl-1-butanol 6.0
Uric acid 5.9
aminomalonic acid 5.9
Nateglinide 5.8
Allylthiourea 5.8
PTMS 5.8
Moexipril 5.7
Insulin 5.6
3,4-dimethoxybenzoic acid 5.6
T undecanoate 5.6
AHA 5.5
HFr 5.5
6-phosphogluconolactone 5.5
Thiazolidinedione 5.5
Eplerenone 5.5
Metformin 5.4
Irbesartan 5.4
Metformin 5.4
Xanthohumol 5.4
Pinitol 5.4
Androstane 5.4
2,5-DCP 5.4
Cryptoxanthin 5.3
Palatinose 5.3
Statin 5.3
Acetophenone 5.3
alpha-CEHC 5.2
Sibutramine 5.2
Stearidonic acid 5.2
Bisdemethoxycurcumin 5.2
Nicotinamide riboside 5.2
Stevioside 5.2
5alpha-cholest-7-en-3beta-ol 5.1
Stevioside 5.1
ITG 5.1
Zingerone 5.1
Campesterol 5.1
Tributyltin chloride 5.1
Hydroxytyrosol 5.1
10-hydroxy-2-decenoic acid 5.0
Novex 5.0
EPA ethyl ester 5.0
more...