Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0948265 (
metabolic syndrome
)
24,271
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
8992
HDL
1727
Sep
1403
adiponectin
1208
leptin
1120
Mol
991
C-reactive protein
811
gut
723
ATP
554
cytokine
414
tumor necrosis factor
373
TNF
369
renin
346
adipokine
318
IL-6
306
peroxisome proliferator-activated receptor
304
hemoglobin
286
Adiponectin
261
peroxisome proliferator-activated receptor gamma
250
CRP
232
interleukin-6
225
albumin
216
AMP-activated protein kinase
200
endoplasmic reticulum
199
glucagon
191
insulin receptor
181
angiotensin II
177
resistin
177
alanine aminotransferase
177
fibrinogen
174
HSD1
170
Leptin
166
plasminogen activator inhibitor-1
163
PPAR
162
apolipoprotein B
157
collagen
144
superoxide dismutase
140
ghrelin
137
epididymal
136
IRS-1
131
more...
Disease
metabolic syndrome
24271
obesity
10003
diabetes
7253
hypertension
5145
type 2 diabetes
4303
cardiovascular disease
3997
dyslipidemia
2742
atherosclerosis
1832
fatty liver
1592
cancer
1361
glucose intolerance
1172
hyperglycemia
1131
abdominal obesity
1100
Nonalcoholic fatty liver
898
hyperlipidemia
831
hyperinsulinemia
782
cirrhosis
723
stroke
665
coronary heart disease
661
coronary artery disease
608
liver disease
605
alcoholic fatty liver
529
hepatocellular carcinoma
523
polycystic ovary syndrome
431
depression
426
heart failure
394
hypercholesterolemia
371
myocardial infarction
368
renal disease
368
hyperuricemia
343
schizophrenia
340
chronic liver disease
329
psoriasis
295
tumor
282
osteoporosis
274
obstructive sleep apnea
256
Alzheimer's disease
251
HIV
234
plaque
231
heart disease
218
more...
Symptom
overweight
1237
pain
133
fatigue
97
cachexia
69
angina
57
starvation
52
sleepiness
48
hepatomegaly
36
hunger
36
weakness
32
anorexia
27
diarrhea
26
insomnia
26
seizures
25
exhaustion
25
snoring
23
anesthesia
21
constipation
18
respiratory distress
16
headache
16
hot flashes
14
menopausal symptoms
13
collapse
13
Depressive symptoms
13
vomiting
12
nausea
12
chest pain
10
polydipsia
10
flushing
10
masculinization
9
discomfort
9
discomfort
9
acute stress
9
hypothermia
9
hypercapnia
9
dyspnea
8
myalgia
8
memory loss
8
polyuria
8
hypotonia
7
more...
Drug
Cardiovasc
375
Dermatol
171
Fructose
128
niacin
111
vitamin E
106
ROS
74
ascorbate
59
ADM
48
lysine
44
ROC
44
caffeine
39
EPA
37
Bifidobacterium
35
Rimonabant
32
Monit
28
Angiotensin II
23
Glucagon
23
Growth hormone
22
Growth hormone
21
Ezetimibe
19
NADH
19
Leaf
19
Rosiglitazone
19
ALA
19
Simvastatin
18
Rosuvastatin
18
MAP
16
IL-2
15
Vitamin A
15
Bezafibrate
15
Estrogens
14
Orlistat
14
ABC
13
Vitamin E
13
Spectrum
12
Asthma
11
citric acid
11
Nitric Oxide
11
Dial
10
nitroglycerin
10
more...
Enzyme
renin
346
alanine aminotransferase
315
AMP-activated protein kinase
306
mitogen-activated protein kinase
223
aspartate aminotransferase
178
superoxide dismutase
165
ACE
141
protein kinase
140
AMPK
123
AMPK
123
catalase
107
ERK
106
lipoprotein lipase
98
NADPH oxidase
92
11beta-hydroxysteroid dehydrogenase
86
gamma-glutamyl transpeptidase
78
NADPH oxidase
78
AST
73
lipase
70
acetyl-CoA carboxylase
58
focal adhesion kinase
58
NO synthase
55
glutathione peroxidase
53
luciferase
51
xanthine oxidase
48
peroxidase
44
protein kinase C
42
alkaline phosphatase
41
phosphoenolpyruvate carboxykinase
41
phosphodiesterase
40
phospholipase A2
39
LPL
37
ATPase
33
calcineurin
32
CPT
30
phosphatidylinositol 3-kinase
30
phosphoenolpyruvate carboxykinase
29
phosphoenolpyruvate carboxykinase
29
creatine kinase
28
tissue plasminogen activator
28
more...
Compound
glucose
6076
Clin
2057
Dec
1648
Insulin
1047
Cholesterol
745
oxygen
629
Cardiol
563
ATP
554
water
508
DNA
457
calcium
396
TNF
369
nitric oxide
363
creatinine
277
vitamin D
274
sodium
269
aldosterone
243
salt
171
acetate
153
phosphate
144
iron
141
silver
139
homocysteine
132
Fructose
128
ethanol
123
Diabetol
115
Diabetol
112
Metformin
112
Metformin
112
arginine
105
potassium
104
Pac
99
Testosterone
99
Testosterone
98
methionine
96
nitrogen
95
DBP
87
DBP
87
PMA
87
tyrosine
85
more...