Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0920652 (skin irritant)
 188 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
OR2B3 17.4
KIAA0117 15.4
TRIM10 14.8
TRIM40 14.6
ribosomal protein L17 13.2
Protocadherin-1 12.8
TRIM31 12.8
calmodulin-like skin protein 12.6
ITPR3 12.3
IER3 11.5
PSMB9 11.3
HLA-DPA1 10.9
DNA-directed RNA polymerase 10.8
Involucrin 10.6
excision repair protein 10.5
EphB3 10.0
claudin 1 10.0
aquaporin-3 9.8
TNF-alpha stimulated 9.7
peroxiredoxin 1 9.6
taurine transporter 9.3
CSL 9.2
Intermedin 9.0
HS1 8.9
HLA-DPB1 8.8
filaggrin 8.7
involucrin 8.6
loricrin 8.4
HET 8.2
Langerin 8.0
TNT 7.7
microphthalmia-associated transcription factor 7.6
functional) 7.6
hairless 7.6
TPA 7.5
ARS 7.2
peroxisome proliferator-activated receptor alpha 7.2
CCL4 7.2
TNFR2 7.2
B7-2 7.2
CD103 7.2
CFC 7.1
RPA 7.1
calcium pump 7.0
interleukin 1 beta 7.0
patched 6.9
CCL3 6.8
promyelocytic leukemia 6.8
ornithine decarboxylase 6.7
HPRT 6.7
transient receptor potential vanilloid 1 6.6
ZAP-70 6.6
IL2 6.4
C30 6.4
eotaxin 6.4
glutamate decarboxylase 6.4
CD83 6.3
CD1a 6.3
major histocompatibility complex class II 6.2
serine protease inhibitor 6.1
MSH 6.1
prostate specific antigen 6.0
C15 6.0
CCL2 6.0
castor 5.9
p44 5.9
PPD 5.9
IL-18 5.8
C-1 5.7
MRC 5.6
K12 5.6
occludin 5.6
acid phosphatase 5.4
COX-1 5.2
cathepsin D 5.2
CXCL10 5.2
CAM 5.1
interleukin 6 5.0
intercellular adhesion molecule-1 5.0
rat) 5.0
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Disease
sulfhemoglobinemia 12.3
Irritant contact dermatitis 10.7
poison ivy 10.2
Carcinogenicity 9.1
herpes labialis 8.7
phosphaturia 8.2
Contact Dermatitis 8.2
hemoglobinuria 8.1
iritis 8.1
skin tumor 8.1
Dermal 7.9
coccidiosis 7.6
parakeratosis 7.6
staphylococcal infection 7.6
dermatitis 7.4
cervical squamous cell carcinoma 7.3
methemoglobinemia 7.2
tubular necrosis 7.1
Adenocarcinoma 7.0
rosacea 6.8
pneumoconiosis 6.7
silicosis 6.5
alkalosis 6.2
papilloma 6.0
acne vulgaris 6.0
emotional stress 5.9
seminal vesicles 5.6
tumor initiation 5.6
lymphoblastic leukemia 5.5
gangrene 5.4
acute promyelocytic leukemia 5.4
carcinogenesis 5.3
CAM 4.9
eczema 4.9
Brown 4.8
skin disease 4.8
hepatitis A 4.7
Blocking 4.2
infestation 4.1
psoriasis 4.0
leprosy 4.0
peripheral neuropathy 4.0
epithelial ovarian cancer 3.9
amyloidosis 3.8
atopic dermatitis 3.7
pruritus 3.5
ash 3.5
fits 3.4
Best 3.3
chronic hepatitis 3.1
SDS 2.7
anemia 2.7
plaque 2.7
neuroblastoma 2.6
cold 2.5
tumor 2.3
gastric cancer 2.2
lymphoma 2.2
GSH 2.2
carcinoma 1.7
rheumatoid arthritis 1.7
depression 1.6
tumorigenesis 1.6
prostate cancer 1.5
adenocarcinoma 1.3
melanoma 1.3
hepatocellular carcinoma 1.2
cancer 0.9
hypertension -0.0
Symptom
skin irritant 17.4
skin irritation 11.9
erythema 7.5
Sedation 7.0
nasal discharge 7.0
skin damage 6.8
sneezing 6.5
rhinorrhea 6.2
cyanosis 5.5
wheezing 5.1
shortness of breath 5.0
lethargy 4.9
thinning 3.9
cough 3.8
ataxia 3.4
hypothermia 3.3
discomfort 2.9
discomfort 2.8
collapse 2.6
anesthesia 1.6
pain -0.6
Drug
Ricinoleic Acid 17.4
Monensin sodium 15.0
Cysteine hydrochloride 14.4
Polysorbate 20 11.5
Castor oil 10.8
Bentonite 9.9
Talc 9.6
Kaolin 9.5
Palmitoyl 9.2
CTC 7.3
CTC 7.0
Capsicum 6.2
MRC 5.6
EPA 5.6
p75 5.4
CAM 4.9
SiO2 4.8
THF 4.4
nitroglycerin 4.3
Dermatol 2.7
Enzyme
CYP27A1 8.3
phytase 8.0
phytase 8.0
ornithine decarboxylase 6.7
glutamate decarboxylase 6.3
ricin 5.7
acid phosphatase 5.3
MDR 5.3
plasmin 4.2
tyrosinase 4.2
glutathione reductase 4.2
protein kinase C 3.8
lactate dehydrogenase 3.5
reverse transcriptase 3.4
glutathione peroxidase 2.9
RNA polymerase 2.3
renin 2.2
focal adhesion kinase 1.9
ERK 1.8
superoxide dismutase 1.5
ATPase 1.4
protein kinase 1.1
mitogen-activated protein kinase 0.8
Compound
Bilobol 15.8
Cysteine hydrochloride 13.9
TCPA 13.5
tetrachloroplatinum 13.2
Rumensin 13.2
Streptomycin sulfate 13.1
4-hydroxy-4-methyl-2-pentanone 13.0
Nicarbazin 12.3
3,4-dimethoxybenzaldehyde 12.1
C10H14 12.0
4,6-dimethylpyrimidine 11.7
4-methoxycinnamic acid 11.7
1,5-pentanediol 11.2
MIBK 11.0
Benzalkonium chloride 10.8
Roxarsone 10.4
Nigericin 10.0
Glycyrrhetinic acid 9.9
Enoxacin 9.9
1,2-ethanediamine 9.9
Neutral Red 9.4
MIBK 9.4
Beryllium 9.3
2-methoxyethanol 9.2
G20 8.7
dodecylbenzene 8.6
Eugenol 8.4
Eugenol 8.4
DNFB 8.3
Betula 8.1
diethyl phthalate 7.9
Sorbitol 7.8
Formate 7.7
Okadaic acid 7.6
Thapsigargin 7.6
malononitrile 7.5
TPA 7.5
boric acid 7.5
1-chloro-2,4-dinitrobenzene 7.4
TPA 7.2
1,2-dimethylhydrazine 7.0
Histidine 6.9
anthracene 6.8
D-glucosamine 6.8
resorcinol 6.4
4-nitrophenyl 6.3
chromate 6.2
25-dihydroxycholecalciferol 6.2
Sodium 6.2
coenzyme Q10 6.2
1-butanol 6.1
benzoic acid 6.0
Penicillin 6.0
Capsaicin 6.0
PPD 5.9
acetone 5.8
PPD 5.8
8-OHdG 5.7
DNP 5.6
EPA 5.6
Triton 5.3
stearic acid 5.3
stearic acid 5.3
Lithium 5.2
2-ethylhexyl 5.2
2-ethylhexyl 5.2
2-ethylhexyl 5.2
stearic acid 5.2
hydroquinone 5.1
MDR 5.1
hydroxylamine 5.0
formaldehyde 5.0
hydrazine 4.9
hydroxylamine 4.9
DBA 4.9
gallic acid 4.9
DDT 4.9
ABL 4.8
retinoic acid 4.8
PLA 4.8
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