Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917816 (mental retardation)
 15,867 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
FMR1 0.008
X-linked 0.006
FMRP 0.004
fragile X mental retardation protein 0.003
MRX 0.003
WAGR 0.003
aniridia 0.002
Rubinstein-Taybi syndrome 0.001
FRAXE 0.001
FMR2 0.001
ATRX 0.001
fatty aldehyde dehydrogenase 0.001
FMR1 protein 0.001
Rett syndrome 0.001
FXR2P 0.001
chromosome 21 0.001
XLMR 0.001
ATRX protein 0.001
MECP2 0.001
MASA 0.001
IL1RAPL1 0.001
FXR1P 0.001
PAK3 0.001
Smith-Lemli-Opitz syndrome 0.001
ARX 0.001
X-linked recessive 0.001
Aristaless-related homeobox 0.001
OPHN1 0.001
SLC6A8 0.001
XNP 0.001
OCRL1 0.001
PQBP1 0.001
FXR2 0.000
VCX-A 0.000
oligophrenin-1 0.000
FXR1 0.000
FISH 0.000
ZFHX1B 0.000
Sotos syndrome 0.000
FACL4 0.000
ARHGEF6 0.000
creatine transporter 0.000
HOPA 0.000
protocadherin 19 0.000
p11 0.000
Fragile X Mental Retardation Protein 0.000
TM4SF2 0.000
RPS6KA3 0.000
PQBP-1 0.000
MIM 0.000
PHF8 0.000
IL1RAPL2 0.000
JARID1C 0.000
MRX30 0.000
MRX9 0.000
PIGV 0.000
L1CAM 0.000
ALDH3A2 0.000
RSK2 0.000
DAXX 0.000
DXS6673E 0.000
Dymeclin 0.000
p21-activated kinase 3 0.000
X-linked) 0.000
CUL4B 0.000
CC2D1A 0.000
alphaPIX 0.000
X-chromosome 0.000
RNA-binding protein 0.000
TSC2 0.000
CLP36 0.000
TSC1 0.000
MCPH1 0.000
FTSJ1 0.000
VCX-C 0.000
MRXS3 0.000
NHS protein 0.000
VCX-B1 0.000
retinoic acid induced 1 0.000
strabismus 0.000
more...
Disease
mental retardation 1.000
mental retardation 0.941
fragile X syndrome 0.017
severe mental retardation 0.004
moderate mental retardation 0.003
developmental delay 0.003
mild mental retardation 0.003
Down syndrome 0.003
epilepsy 0.002
autism 0.002
FRAXA 0.002
FRAXE 0.002
cerebral palsy 0.002
profound mental retardation 0.001
ATRX 0.001
macrocephaly 0.001
Rett syndrome 0.001
developmental disabilities 0.001
phenylketonuria 0.001
congenital hypothyroidism 0.001
Congenital hypothyroidism 0.001
Cohen syndrome 0.001
tuberous sclerosis 0.001
trisomy 0.001
Smith-Lemli-Opitz syndrome 0.001
Bardet-Biedl syndrome 0.001
Partington syndrome 0.001
KMS 0.001
X-linked hydrocephalus 0.001
ichthyosis 0.001
lissencephaly 0.001
Angelman syndrome 0.001
Williams syndrome 0.001
deafness 0.001
genetic disorder 0.001
Prolidase deficiency 0.001
hypogonadism 0.001
spastic diplegia 0.001
Danon disease 0.001
Lowe syndrome 0.001
Sotos syndrome 0.001
Costello syndrome 0.001
Cornelia de Lange syndrome 0.001
MRX2 0.001
FGS 0.000
spastic paraplegia 0.000
CLS 0.000
Laurence-Moon-Biedl syndrome 0.000
ichthyosis 0.000
HCG 0.000
Wolf-Hirschhorn syndrome 0.000
homocystinuria 0.000
blepharophimosis 0.000
pachygyria 0.000
49,XXXXY syndrome 0.000
self-injurious behavior 0.000
brachycephaly 0.000
MRX3 0.000
Seckel syndrome 0.000
Phenylketonuria 0.000
MRX30 0.000
Richner-Hanhart syndrome 0.000
EFMR 0.000
learning disability 0.000
Norrie disease 0.000
mental handicap 0.000
MRX19 0.000
MRX16 0.000
anhidrosis 0.000
alpha thalassemia 0.000
Gillespie syndrome 0.000
FAS 0.000
Lesch-Nyhan syndrome 0.000
Maternal phenylketonuria 0.000
MRX9 0.000
hyperphenylalaninemia 0.000
HSAN IV 0.000
monosomy 8p 0.000
delayed speech 0.000
hydrocephalus 0.000
more...
Symptom
hypotonia 0.004
seizures 0.002
ataxia 0.001
cerebellar ataxia 0.000
spasticity 0.000
prominent nose 0.000
dystonia 0.000
weakness 0.000
dysarthria 0.000
hemiplegia 0.000
myoclonus 0.000
tremor 0.000
Posturing 0.000
athetosis 0.000
ataxic gait 0.000
drooling 0.000
hepatosplenomegaly 0.000
paraparesis 0.000
Dysdiadochokinesis 0.000
intention tremor 0.000
hypertonia 0.000
delayed language development 0.000
Spastic hemiplegia 0.000
Respiratory abnormalities 0.000
Tandem gait 0.000
partial seizure 0.000
enuresis 0.000
constipation 0.000
hyperacusis 0.000
Hypersomnolence 0.000
photophobia 0.000
clumsiness 0.000
catatonia 0.000
paresis 0.000
chromosome marker 0.000
Synkinesis 0.000
abnormal breathing 0.000
anesthesia 0.000
chorea 0.000
chronic constipation 0.000
tonic-clonic seizure 0.000
lethargy 0.000
Physical findings 0.000
incoordination 0.000
pachyonychia 0.000
vomiting 0.000
localized erythema 0.000
ophthalmoplegia 0.000
agitation 0.000
tonic seizure 0.000
hepatomegaly 0.000
fasciculation 0.000
abnormal gait 0.000
polyuria 0.000
polydipsia 0.000
clonus 0.000
bedwetting 0.000
musculoskeletal disability 0.000
carpopedal spasm 0.000
monoplegia 0.000
Kernig's sign 0.000
Psychiatric symptoms 0.000
generalized erythema 0.000
pain 0.000
DNA marker 0.000
General symptoms 0.000
physical appearance 0.000
Bitot's spots 0.000
pallor 0.000
sleepiness 0.000
staggering gait 0.000
thinning 0.000
splenomegaly 0.000
anosmia 0.000
cyanosis 0.000
headache 0.000
situational stress 0.000
Behavioral symptoms 0.000
regurgitation 0.000
consciousness disturbance 0.000
more...
Drug
Quetiapine hemifumarate 0.000
Zmax 0.000
Calcium hopantenate 0.000
Fosfluconazole 0.000
Galsulfase 0.000
Thyradin 0.000
AGG 0.000
CXN 0.000
Azithromycin 0.000
Idursulfase 0.000
Diastat 0.000
Stiripentol 0.000
DM1 0.000
Sodium valproate 0.000
Namenda 0.000
Dermatol 0.000
Collodion 0.000
Valganciclovir 0.000
Amlexanox 0.000
Zinc acetate 0.000
Ethanol 0.000
BH4 0.000
Galactose 0.000
Spectrum 0.000
Cobalamin 0.000
lysine 0.000
Tiopronin 0.000
CSF 0.000
Sonata 0.000
Phenytoin 0.000
Sodium benzoate 0.000
Vitamin B 0.000
Thioridazine 0.000
Spectrum 0.000
DMAA 0.000
OTC 0.000
CLS 0.000
Pyridoxal phosphate 0.000
Meconium 0.000
OTC 0.000
AVC 0.000
Vitamin B12 0.000
Atomoxetine 0.000
Singular 0.000
PTH 0.000
Frontal 0.000
Ammonium chloride 0.000
Asn 0.000
ABC 0.000
L-tyrosine 0.000
Depo-Provera 0.000
Palmitoyl 0.000
Isotretinoin 0.000
Adenosine deaminase 0.000
CPO 0.000
Senna 0.000
Copaxone 0.000
Senna 0.000
Growth hormone 0.000
Ganciclovir 0.000
Growth hormone 0.000
Piracetam 0.000
HPMPC 0.000
Retinoic Acid 0.000
Zonisamide 0.000
VCR 0.000
Doyle 0.000
pyridoxal phosphate 0.000
Botox 0.000
ENT 0.000
Aminoguanidine 0.000
Parkin 0.000
TTC 0.000
Parkin 0.000
Orphan 0.000
BTC 0.000
Tuberculin 0.000
Metrizamide 0.000
linolenate 0.000
BLM 0.000
more...
Enzyme
7-dehydrocholesterol reductase 0.000
prolidase 0.000
glycine amidinotransferase 0.000
aspartylglucosaminidase 0.000
guanidinoacetate methyltransferase 0.000
phenylalanine hydroxylase 0.000
cystathionine beta-synthase 0.000
EC 1.2.1.48 0.000
hypoxanthine-guanine phosphoribosyltransferase 0.000
spermine synthase 0.000
adenylosuccinate lyase 0.000
glycerol kinase 0.000
6-pyruvoyltetrahydropterin synthase 0.000
Lod 0.000
NADH-cytochrome b5 reductase 0.000
uridyltransferase 0.000
serum carnosinase 0.000
histone demethylase 0.000
succinic semialdehyde dehydrogenase 0.000
alpha-L-iduronidase 0.000
neurosin 0.000
aspartoacylase 0.000
inosine triphosphatase 0.000
CYP27A1 0.000
glutamate formiminotransferase 0.000
alpha-N-acetylglucosaminidase 0.000
biotinidase 0.000
dihydroxyacetone phosphate acyltransferase 0.000
CTD kinase 0.000
ornithine transcarbamylase 0.000
arylsulfatase 0.000
BCKDH 0.000
4-hydroxyphenylpyruvate dioxygenase 0.000
dihydropteridine reductase 0.000
sarcosine dehydrogenase 0.000
phosphomannomutase 0.000
iduronate-2-sulfatase 0.000
trans-2-enoyl-CoA reductase 0.000
phosphoinositide 5-phosphatase 0.000
sulfite oxidase 0.000
sulfite oxidase 0.000
AIR synthetase 0.000
phytanoyl-CoA hydroxylase 0.000
tyrosine aminotransferase 0.000
gamma-glutamyl phosphate reductase 0.000
dimethylglycine dehydrogenase 0.000
alpha-mannosidase 0.000
branched-chain alpha-keto acid dehydrogenase 0.000
creatine kinase 0.000
cystathionine gamma-synthase 0.000
galactose-1-phosphate uridylyltransferase 0.000
LIS 0.000
glucoamylase 0.000
dihydroxyacetone-phosphate acyltransferase 0.000
ribose-5-phosphate isomerase 0.000
PHD 0.000
site-1 protease 0.000
guanylate kinase 0.000
histidase 0.000
3-mercaptopyruvate sulfurtransferase 0.000
mitogen-activated protein kinase 0.000
N-acetylglucosaminyltransferase II 0.000
tripeptidyl peptidase 0.000
protein kinase 0.000
urocanase 0.000
sulfatase 0.000
diphosphomevalonate decarboxylase 0.000
proline oxidase 0.000
phosphoglycerate kinase 0.000
sialidase 0.000
proline dehydrogenase 0.000
protoporphyrinogen oxidase 0.000
ornithine aminotransferase 0.000
amylo-1,6-glucosidase 0.000
CLK1 0.000
KAR 0.000
thyroid peroxidase 0.000
ubiquitin-protein ligase 0.000
ERK 0.000
pyruvate dehydrogenase phosphatase 0.000
more...
Compound
Retard 0.008
MCA 0.000
MCA 0.000
Microcephalin 0.000
Guanidinoacetic acid 0.000
DNA 0.000
L-2-Hydroxyglutaric acid 0.000
DMD 0.000
Butoctamide hydrogen succinate 0.000
Caprin 0.000
DHC 0.000
Clin 0.000
Phe 0.000
Dec 0.000
Creatine 0.000
Tuberin 0.000
His 0.000
DSM 0.000
Phenylpyruvate 0.000
3-Hydroxyglutaric acid 0.000
Hydantoin 0.000
X 34 0.000
S-sulfocysteine 0.000
glutamic gamma-semialdehyde 0.000
PAC 0.000
adenylosuccinate 0.000
iodine 0.000
3-methyl-2-oxopentanoate 0.000
Neuronal 0.000
glutamate 0.000
Phenylalanine 0.000
homocysteine 0.000
MAOA 0.000
D-Proline 0.000
Thyroid 0.000
TSH 0.000
hydroxyglutarate 0.000
Triparanol 0.000
Bufotenine 0.000
N-acetylaspartic acid 0.000
Vigabatrin 0.000
GTP 0.000
tyrosine 0.000
AMPA 0.000
diphenylarsinic acid 0.000
Sudafed 0.000
N-acetylaspartic acid 0.000
Methylmalonic acid 0.000
6-pyruvoyltetrahydropterin 0.000
Homocarnosine 0.000
alpha-hydroxyisovaleric acid 0.000
Sudafed 0.000
ethanol 0.000
Valproic acid 0.000
mercaptopyruvate 0.000
GABA 0.000
GABA 0.000
Risperidone 0.000
Levetiracetam 0.000
SAICAR 0.000
arginine 0.000
Methylazoxymethanol 0.000
N-acetylaspartate 0.000
Cystathionine 0.000
proline 0.000
Cystathionine 0.000
isoleucine 0.000
L-methylmalonyl-CoA 0.000
pyrroline-5-carboxylate 0.000
isoleucine 0.000
valine 0.000
Homogentisate 0.000
BMD 0.000
TSC 0.000
Galactose 0.000
methionine 0.000
MSTFA 0.000
CZP 0.000
folinic acid 0.000
Zinc acetate 0.000
more...