Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0917816 (mental retardation)
15,867 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein X-linked 1316 Sep 1026 Mol 671 FMR1 413 MRI 289 FMRP 268 She 260 FISH 237 Rett syndrome 223 chromosome 21 207 fragile X mental retardation protein 176 telomeric 163 aniridia 145 X-linked recessive 143 RNA-binding protein 125 p11 117 axonal 113 ATRX 112 cryptic 111 X-chromosome 110 strabismus 108 MECP2 108 MRX 105 histone 94 thyroid hormone 93 MIM 90 Rubinstein-Taybi syndrome 89 ATR 86 WAGR 83 insulin 77 Smith-Lemli-Opitz syndrome 76 p13 74 TSC2 72 UTR 70 FRAXE 67 Rho 65 TSC1 64 p22 62 CA1 62 dystrophin 61 endoplasmic reticulum 59 GABA 59 p21 56 metabotropic glutamate receptor 52 hypoxanthine-guanine phosphoribosyltransferase 51 p53 51 mTOR 50 Pol 49 ARX 49 reductase 48 olfactory 48 amyloid precursor protein 48 fatty aldehyde dehydrogenase 47 neurofibromatosis 46 ATP 45 ATPase 43 FMR1 protein 43 WT1 43 FMR2 42 GTG 42 CSF 41 ubiquitin 40 Sotos syndrome 40 Y chromosome 38 phenylalanine hydroxylase 38 GTPase 37 RNA binding protein 36 phosphatase 36 Mot 36 DAG 35 RSH 35 XLMR 35 ICD 35 L1CAM 35 growth hormone 35 creatine kinase 35 creatine transporter 34 DCX 34 collagen 34 DMD 33 more...

Disease mental retardation 15867 mental retardation 15395 epilepsy 1529 fragile X syndrome 992 autism 986 Down syndrome 776 developmental delay 627 cerebral palsy 514 obesity 361 schizophrenia 331 deafness 313 severe mental retardation 305 cancer 293 genetic disorder 291 developmental disabilities 291 tuberous sclerosis 280 trisomy 266 dysplasia 252 Rett syndrome 244 tumor 244 hydrocephalus 235 psychosis 230 mental illness 230 phenylketonuria 228 Alzheimer's disease 223 cognitive impairment 223 Autism 222 mild mental retardation 217 depression 215 hypogonadism 213 hypothyroidism 206 encephalopathy 205 dementia 203 HCG 187 cleft palate 185 moderate mental retardation 182 congenital hypothyroidism 177 fits 176 macrocephaly 173 heart disease 171 thalassemia 164 ichthyosis 155 aggression 154 strabismus 146 blindness 144 WT1 143 Williams syndrome 143 Syndrome 140 diabetes 136 FAS 136 cataract 124 ichthyosis 121 prolapse 119 myopathy 118 scoliosis 113 ATRX 112 West 111 lissencephaly 108 failure to thrive 106 spastic paraplegia 106 profound mental retardation 105 ADHD 104 retinitis pigmentosa 102 Bardet-Biedl syndrome 102 learning disability 101 Angelman syndrome 101 cytomegalovirus 98 tetraplegia 97 brain atrophy 96 nystagmus 93 malnutrition 92 Duchenne muscular dystrophy 91 sensorineural hearing loss 90 muscular dystrophy 87 Smith-Lemli-Opitz syndrome 86 craniosynostosis 85 hypertension 84 hemiparesis 84 glaucoma 82 FRAXA 81 more...

Symptom seizures 1539 hypotonia 586 ataxia 400 weakness 208 spasticity 200 cerebellar ataxia 155 pain 134 anesthesia 130 tremor 124 dystonia 98 myoclonus 63 hemiplegia 63 dysarthria 63 vomiting 63 hepatosplenomegaly 52 headache 52 constipation 51 diarrhea 43 paraparesis 39 agitation 37 paresis 31 lethargy 28 sleepiness 26 hepatomegaly 25 thinning 24 hypertonia 23 respiratory distress 22 splenomegaly 22 enuresis 21 abdominal pain 20 drooling 20 ophthalmoplegia 19 ataxic gait 19 overweight 19 regurgitation 18 chorea 17 insomnia 16 photophobia 16 polyuria 16 fatigue 16 incoordination 15 hypothermia 14 partial seizure 14 cyanosis 13 athetosis 13 polydipsia 13 chronic constipation 13 tonic-clonic seizure 13 catatonia 13 dyspnea 12 intention tremor 12 stigma 12 pallor 11 analgesia 11 fasciculation 11 abnormal gait 10 prominent nose 10 physical appearance 9 clumsiness 9 myalgia 9 nausea 8 dizziness 8 hyperacusis 8 anosmia 8 cough 8 apathy 7 ENT 7 hunger 7 DNA marker 7 anorexia 7 cachexia 7 collapse 7 clonus 7 memory loss 6 hemoptysis 6 Physical findings 6 starvation 6 snoring 6 spasm 6 vertigo 6 more...

Drug Dermatol 164 lysine 57 CSF 41 Ethanol 27 Zmax 17 Azithromycin 17 Spectrum 16 Spectrum 16 AGG 14 Asn 13 DM1 13 ABC 11 BH4 10 Cardiovasc 10 PTH 10 NADH 9 Leaf 9 lactose 9 ENT 8 Galactose 8 vitamin E 7 Phenytoin 7 Vitamin B 6 Sodium valproate 5 Growth hormone 5 Growth hormone 5 Frontal 5 L-tyrosine 5 MAP 5 THF 5 caffeine 4 Mutagen 4 OTC 4 Vitamin B12 4 pyridoxal phosphate 4 CAM 4 OTC 4 EPA 4 FAD 3 ADM 3 Parkin 3 ROC 3 TTC 3 Monit 3 p75 3 Cobalamin 3 Parkin 3 Nephron 3 ETS 3 nitroglycerin 3 VCR 3 Isotretinoin 2 Gel 2 CTX 2 IFN-gamma 2 Singular 2 Depo-Provera 2 Histamine 2 CTX 2 CPR 2 BLM 2 Adenosine deaminase 2 Alliance 2 CTX 2 Meconium 2 Thioridazine 2 Portal 2 Valganciclovir 2 CLS 2 ascorbate 2 Angiotensin II 2 ampicillin 2 citric acid 2 Calcium hopantenate 2 Stiripentol 2 Propofol 2 Dial 2 CTA 2 ROS 2 Bayer 2 more...

Enzyme mitogen-activated protein kinase 78 protein kinase 70 ERK 64 ATPase 47 creatine kinase 40 phenylalanine hydroxylase 40 hypoxanthine-guanine phosphoribosyltransferase 40 superoxide dismutase 36 catalase 33 prolidase 32 cystathionine beta-synthase 28 RNA polymerase 27 MEK 23 alkaline phosphatase 23 7-dehydrocholesterol reductase 21 neuraminidase 19 proteasome 17 ornithine transcarbamylase 16 glycine amidinotransferase 16 luciferase 16 beta-galactosidase 15 glycerol kinase 15 glutathione peroxidase 15 histone demethylase 15 demethylase 14 sulfatase 13 arylsulfatase 13 NOS 12 trypsin 12 calcineurin 12 glucoamylase 12 guanidinoacetate methyltransferase 12 protein kinase C 12 beta-glucuronidase 12 caspase-3 12 tyrosine aminotransferase 12 NADH-cytochrome b5 reductase 12 sialidase 11 isocitrate dehydrogenase 11 choline acetyltransferase 11 alcohol dehydrogenase 11 aspartylglucosaminidase 11 alpha-mannosidase 11 reverse transcriptase 11 focal adhesion kinase 11 acetylcholinesterase 11 thyroid peroxidase 11 isocitrate dehydrogenase 10 renin 10 carbonic anhydrase 10 complex I 10 CYP27A1 10 phosphoglycerate kinase 10 cytochrome oxidase 10 tyrosine hydroxylase 9 glucose-6-phosphate dehydrogenase 9 monoamine oxidase 9 alpha-L-iduronidase 9 APC 8 aldehyde dehydrogenase 8 spermine synthase 8 succinic semialdehyde dehydrogenase 8 pyruvate dehydrogenase 8 biotinidase 8 peroxidase 8 adenylosuccinate lyase 8 AMP-activated protein kinase 8 histone acetyltransferase 7 methylenetetrahydrofolate reductase 7 dihydropteridine reductase 7 aldehyde dehydrogenase 7 STR 7 alanine aminotransferase 7 kinesin 7 DNA polymerase 7 Lod 7 CaMKII 7 PHD 7 arginase 7 phosphodiesterase 7 more...

Compound Dec 1075 DNA 972 Clin 969 Retard 742 His 187 Phe 174 calcium 137 ethanol 126 water 118 glutamate 115 tyrosine 111 oxygen 105 DSM 100 iodine 99 arginine 94 MCA 90 MCA 90 glucose 89 sodium 66 methionine 65 serine 64 lysine 62 GTP 61 GABA 59 GABA 59 phosphate 55 zinc 54 sulfate 52 proline 52 leucine 51 galactose 51 Thyroid 50 TSH 48 ATP 46 Neuronal 45 homocysteine 45 potassium 45 urea 44 iron 42 creatinine 42 salt 39 cysteine 38 alanine 36 threonine 35 Ile 35 AMPA 34 copper 34 DMD 33 valine 33 ammonia 31 tryptophan 30 cAMP 29 Pac 29 gamma-aminobutyric acid 29 isoleucine 28 isoleucine 28 tryptophan 28 glutamine 28 tryptophan 27 nitric oxide 27 tryptophan 27 NMDA 26 Cardiol 25 acetate 24 PAC 24 Creatine 23 silver 23 mercury 22 Cereb 21 AMP 21 A 3 20 Asp 20 ACTH 20 CoA 19 hydrogen 19 Valproic acid 18 nitrogen 17 Gly 16 asparagine 16 barium 16 more...

---