Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0917801 (insomnia)
10,606 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 650 REM 283 prion 212 orexin 208 GABA 200 CBT 167 prion protein 162 She 108 PrP 98 Mol 89 MRI 62 C30 62 ICD 49 Gen 48 Orexin 46 PRNP 45 insulin 42 GABA(A) receptor 37 hemoglobin 35 5-hydroxytryptamine 35 dream 35 cytokine 35 Pol 34 prolactin 33 CGI 31 beta-endorphin 30 reserved 29 MT2 29 MT1 27 Men 27 interferon 27 cytochrome P450 26 ANOVA 26 CSF 26 5-HT2A 24 ADHD 24 5-HT1A 24 C-reactive protein 23 APA 21 cage 20 brain-derived neurotrophic factor 19 TNF 19 alkaline phosphatase 19 acetylcholinesterase 19 ferritin 19 SWS 18 CPAP 18 PSG 17 IL-6 17 CYP3A4 17 albumin 17 GSD 16 OX1R 16 ACTH 16 olfactory 16 amyloid precursor protein 16 Mil 16 gut 15 opioid receptor 15 OX2R 15 growth hormone 15 chronic renal failure 15 leptin 15 interleukin-6 15 Mot 15 IFN 14 CD4 14 tumor necrosis factor 14 GAD 14 SAS 13 FSH 13 lipopolysaccharide 13 CLOCK 13 San 13 axonal 13 NMR 12 superoxide dismutase 12 MM2 12 aspartate aminotransferase 12 glutamic acid decarboxylase 12 more...

Disease depression 2436 sleep disorders 1416 sleep disturbances 875 cancer 449 major depressive disorder 402 sleep apnea 365 restless legs syndrome 354 hypertension 318 obstructive sleep apnea 309 psychosis 307 dementia 288 posttraumatic stress disorder 284 mental illness 276 anxiety disorders 260 narcolepsy 256 schizophrenia 246 Parkinson's disease 223 epilepsy 217 hallucinations 215 Creutzfeldt-Jakob disease 211 diabetes 199 Alzheimer's disease 197 cognitive impairment 192 obesity 190 chronic pain 187 suicide 177 xerostomia 177 Sleep disturbance 169 addiction 136 confusion 131 stroke 123 Gerstmann 120 breast cancer 113 delirium 108 pruritus 103 bipolar disorder 100 cardiovascular disease 100 migraine 95 psychological distress 91 mania 91 sexual dysfunction 86 movement disorder 86 aggression 83 asthma 82 Chronic insomnia 81 fibromyalgia 80 delusions 80 HIV 79 alcoholism 77 neuroticism 76 substance abuse 74 affective disorder 74 ADHD 73 autism 72 memory impairment 69 anemia 65 cold 65 tumor 62 fits 62 multiple sclerosis 61 kuru 61 parasomnia 60 behavior disorder 59 rash 58 amnesia 55 AIDS 55 REM sleep behavior disorder 55 parkinsonism 54 cataplexy 54 suicide attempts 54 sleepwalking 54 Syndrome 53 spongiform encephalopathy 52 substance use 51 encephalitis 51 rumination 50 panic disorder 50 chronic obstructive pulmonary disease 50 osteoporosis 49 ICD 49 more...

Symptom insomnia 10606 sleepiness 1104 fatigue 990 pain 813 headache 779 nausea 499 agitation 433 dizziness 346 anorexia 279 seizures 233 vomiting 219 hypersomnia 216 constipation 199 diarrhea 191 tremor 152 dyspnea 127 weakness 121 snoring 104 discomfort 84 nausea and vomiting 80 ataxia 73 myoclonus 72 hot flushes 68 cough 67 discomfort 65 asthenia 65 tinnitus 64 vertigo 63 back pain 63 hot flashes 63 abdominal pain 63 myalgia 62 decreased appetite 60 Poor sleep 57 menopausal symptoms 56 paresthesia 53 exhaustion 50 arthralgia 49 lethargy 48 anesthesia 45 memory loss 42 dystonia 39 Ill 36 eds 35 hangover 35 apathy 34 hopelessness 33 numbness 33 enuresis 32 overweight 30 analgesia 28 low back pain 28 Depressive symptoms 26 forgetfulness 24 spasticity 24 excessive sweating 24 syncope 22 night sweats 22 bradykinesia 20 Rebound insomnia 20 chills 20 chest pain 20 dysarthria 20 acute stress 19 muscle cramps 19 tingling 18 Sedation 18 chorea 18 cerebellar ataxia 17 shortness of breath 17 blurred vision 17 stigma 17 cancer pain 15 flushing 15 hunger 15 bone pain 14 lassitude 14 shoulder pain 14 angina 14 stomach pain 14 more...

Drug caffeine 120 Zonisamide 54 Ramelteon 46 Triazolam 37 Spectrum 33 CSF 26 Flurazepam 23 Mirtazapine 23 Dermatol 22 Portal 19 Eszopiclone 18 Duloxetine 18 Ambien 18 Domperidone 18 Cardiovasc 16 Asthma 14 Gabapentin 14 Modafinil 12 Clonidine 11 Monit 11 Leaf 10 Brotizolam 9 Diurnal 9 Moclobemide 9 Lormetazepam 9 Donepezil 8 Agomelatine 8 Pramipexole 8 Spectrum 8 Indiplon 8 Dial 8 Pramipexole 8 Trimipramine 7 Atomoxetine 7 Flunitrazepam 7 Check 7 ACT 7 Ethanol 6 Paliperidone 6 TAK 6 MT6 6 Escitalopram 5 Dormicum 5 9-THC 5 Pregabalin 5 Asn 5 CAM 5 niacin 5 Ofloxacin 5 Loratadine 5 Ritalin 4 Reboxetine 4 AZT 4 Oxaliplatin 4 Catapres 4 AZT 4 Trazodon 4 Lovastatin 4 APD 4 nitroglycerin 4 ascorbate 4 Sonata 4 Glycyrrhiza 4 Orlistat 4 IL-2 3 Truvada 3 Alarin 3 ENT 3 Triad 3 Lisdexamfetamine dimesylate 3 Acamprosate 3 vitamin E 3 Digitalis 3 ICI 3 Reserpine 3 Longgu 3 lysine 3 ALA 3 Paliperidone palmitate 3 Codeine 3 more...

Enzyme monoamine oxidase 45 acetylcholinesterase 26 ERK 20 alkaline phosphatase 19 CYP3A4 17 alanine aminotransferase 17 aspartate aminotransferase 14 superoxide dismutase 13 cholinesterase 11 catalase 11 creatine kinase 10 reverse transcriptase 10 proteinase K 9 ACS 9 lactate dehydrogenase 9 focal adhesion kinase 9 gamma-glutamyl transpeptidase 8 tryptophan hydroxylase 8 phosphodiesterase 7 adenylate cyclase 7 mitogen-activated protein kinase 7 ATPase 6 glutathione peroxidase 6 thyroid peroxidase 5 protein kinase 5 P-glycoprotein 4 N-acetyltransferase 4 glutathione reductase 4 AOR 4 renin 4 CPT 4 CPT 4 caspase-3 4 calcineurin 4 CPT 4 choline acetyltransferase 4 lipase 4 carbonic anhydrase 3 botulinum neurotoxin 3 aldehyde dehydrogenase 3 GABA transaminase 3 Alternating 3 NO synthase 3 arylalkylamine N-acetyltransferase 3 caspase-8 3 tyrosine hydroxylase 3 MCS 3 AMPK 2 ornithine transcarbamylase 2 AMP-activated protein kinase 2 acetylserotonin O-methyltransferase 2 succinate dehydrogenase 2 PMT 2 aldehyde dehydrogenase 2 CFI 2 glutathione S-transferase 2 aldehyde dehydrogenase 2 BIS 2 ACE 2 SOR 2 IKK 2 AMPK 2 PARP 2 peroxidase 2 phospholipase C 2 urokinase-type plasminogen activator 2 aldehyde dehydrogenase 2 alcohol dehydrogenase 2 GRK5 2 aldehyde dehydrogenase 2 DAT 2 CaMKII 2 LDT 2 GSK 2 glutaminase 1 ornithine aminotransferase 1 CEP 1 ATP synthase 1 SOR 1 copalyl diphosphate synthase 1 more...

Compound Clin 1279 Dec 703 DSM 245 GABA 207 GABA 202 Melatonin 158 caffeine 120 Zolpidem 119 5-HT 110 ethanol 103 oxygen 98 water 91 sodium 88 gamma-aminobutyric acid 67 tryptophan 65 glucose 65 tryptophan 65 tryptophan 64 tryptophan 64 calcium 63 noradrenaline 61 methionine 60 DNA 45 glutamate 43 His 42 Trazodone 41 iron 40 potassium 37 creatinine 36 Zaleplon 31 Diazepam 30 5-hydroxytryptophan 29 acetate 29 Cardiol 29 Bupropion 27 valine 25 Mirtazapine 23 mercury 23 methanol 22 nitric oxide 20 Temazepam 20 acetonitrile 19 TNF 19 urea 18 Quetiapine 18 hydrogen 17 sulfate 17 ACTH 16 Aripiprazole 16 CO2 16 salt 16 nitrogen 16 phosphate 16 Midazolam 15 L-DOPA 15 Nicotine 15 CES 14 Optimal 14 Estrogen 13 5-HTP 13 Quazepam 13 Clonazepam 13 Risperidone 12 ethyl acetate 12 Lorazepam 12 Asp 12 5-HTP 12 tyrosine 12 Piper 12 6-12 11 Malondialdehyde 11 Sertraline 11 Estrogen 11 CPA 11 aspartic acid 11 Nitrazepam 10 aspartic acid 10 formic acid 10 formic acid 10 formic acid 10 more...

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