Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917801 (insomnia)
 10,606 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Beta-actin-like protein 2 11.6
prion protein precursor 11.6
Urotensin 2 10.6
HEBP2 10.0
SNX32 10.0
DALRD3 9.6
WDR27 9.6
Dopamine receptor D3 9.6
FREM3 9.2
contactin-associated protein 2 9.0
HCRTR2 9.0
TMEM132E 9.0
FBXO15 8.7
Meis homeobox 1 8.7
5-hydroxytryptamine (serotonin) receptor 2C 8.7
DORA 8.7
Kue 8.6
OX2R 8.4
Voltage-gated potassium channel 8.2
PLEKHM2 8.1
SEC61B 8.1
TSHZ2 8.1
INADL 8.0
CBT 7.9
PRNP 7.9
APSS 7.9
G5PR 7.9
APBB2 7.6
OX1R 7.6
orexin 7.4
Caspr2 7.3
ATP5H 7.3
KIRREL3 7.3
REM 7.3
PSG 7.2
MPS2 7.2
MDGA1 7.1
GPR50 7.0
OX2 6.9
HNMT 6.9
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Disease
Sleep State Misperception 11.6
Intrinsic Sleep Disorders 11.6
Inadequate Sleep Hygiene 11.6
Primary hypersomnia 11.6
Septum pellucidum cyst 11.6
Paradoxical insomnia 11.6
Nonorganic insomnia 11.6
Idiopathic insomnia 11.6
Psychophysiological insomnia 11.6
Chronic insomnia 11.4
Primary insomnia 11.4
Other sleep disorders 10.7
aggressive outburst 10.6
Manic behavior 10.6
Agitated Depression 10.2
Delayed sleep phase 10.2
Difficulty falling asleep 10.1
Periodic Limb Movement Disorder 10.1
disorders of initiating or maintaining sleep 10.0
Confusional arousals 10.0
Insufficient sleep syndrome 10.0
BD syndrome 10.0
Recurrent depressive disorder 9.6
parasitophobia 9.6
Morvan 9.5
pressured speech 9.5
Delayed sleep phase syndrome 9.4
Sleep disturbance 9.3
sleep disorders 9.2
Dentatorubropallidoluysian atrophy 9.2
restless legs syndrome 9.1
parasomnia 9.0
Gerstmann 9.0
Drug-induced delirium 9.0
nervous exhaustion 9.0
Situational anxiety 9.0
sleep disturbances 8.9
sleep terrors 8.9
sleepwalking 8.8
racing thoughts 8.8
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Symptom
insomnia 11.6
Persistent insomnia 11.6
ringing in ear 11.6
burning sensation in eye 11.6
Secondary Insomnia 11.6
Rebound insomnia 11.4
Transient insomnia 11.2
Drug withdrawal symptoms 10.6
hypersomnia 9.3
CNS symptom 9.2
Oral discomfort 9.2
unable to sleep 9.0
tactile hallucination 9.0
Biot's breathing 9.0
Poor sleep 8.9
Early morning awakening 8.7
Pain worsened 8.4
upset stomach 8.3
Withdrawal Symptom 8.2
hangover 8.2
sleepiness 8.0
feeling tired 7.9
feeling exhausted 7.6
prickling sensation 7.6
stomach cramps 7.6
hot flashes 7.5
Vaginal dryness 7.4
hot flushes 7.4
painful erections 7.3
Crawling 7.3
decreased appetite 7.3
lassitude 7.2
Psychotic Symptoms 7.2
leg cramps 7.2
feeling depressed 7.0
Cutaneous allodynia 7.0
Tired 7.0
epigastric distress 7.0
excessive sweating 7.0
Cancer Fatigue 6.9
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Drug
Contomin 11.6
Clomipramine HCL 11.6
Ramelteon 10.8
ProSom 10.6
Pexiganan acetate 10.6
Hydroxyzine pamoate 10.6
Pyrethia 10.6
Ambien 10.4
Indiplon 10.4
Flurazepam hydrochloride 10.2
Eszopiclone 10.2
Tiamenidine 10.0
Norgesic 10.0
Tandospirone citrate 10.0
Trazodon 9.7
Insidon 9.6
Longgu 9.3
Lormetazepam 9.2
Oxilorphan 9.0
Flurazepam 8.9
MT6 8.8
Requip 8.7
Uncaria hook 8.7
Zonisamide 8.7
Triazolam 8.7
Brotizolam 8.7
Trimipramine 8.6
Clopamide 8.6
Timiperone 8.4
Focalin 8.4
Geodon 8.4
Paliperidone palmitate 8.3
Methysergide maleate 8.2
Requip 8.2
Geodon 8.1
Lisdexamfetamine dimesylate 8.0
Diclectin 7.9
CXN 7.9
Mirtazapine 7.8
Brofaromine 7.7
more...
Enzyme
copalyl diphosphate synthase 5.9
acetylserotonin O-methyltransferase 5.8
MSAS 5.7
LDT 5.7
AFR 4.9
DAHP synthase 4.7
IOR 4.3
tyrosine decarboxylase 4.0
PFI 3.9
PMT 3.9
GM3 synthase 3.8
glutaryl-CoA dehydrogenase 3.8
tryptophan hydroxylase 3.8
arylalkylamine N-acetyltransferase 3.8
monoamine oxidase 3.7
SOR 3.6
MCS 3.5
GABA transaminase 3.5
SOI 3.3
dimethylarginine dimethylaminohydrolase 3.3
SOR 3.1
CYP3A4 3.0
SNO 3.0
CFI 2.9
AOR 2.8
proteinase K 2.7
BIS 2.6
Alternating 2.5
CYP27A1 2.5
SPT 2.5
GRK5 2.4
N-acetyltransferase 2.4
thyroid peroxidase 2.3
botulinum neurotoxin 2.2
NAT 2.2
monoacylglycerol lipase 2.1
SMP 2.1
ornithine aminotransferase 2.1
DAT 2.0
aldehyde oxidase 2.0
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Compound
Phenindamine 11.6
Zaleplon 10.5
Quazepam 10.1
Levomethadyl acetate 10.0
Dalmane 9.9
Zolpidem 9.6
Estazolam 9.6
7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one 9.6
3,4,5-Trimethoxycinnamic acid 9.0
Trazodone 8.9
Temazepam 8.9
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one 8.7
Valerenic acid 8.5
Trimeprazine 8.5
2,4-dichloropyrimidine 8.4
Bupropion hydrochloride 8.3
Doxylamine 8.3
Tabernanthine 8.2
cyclodecanone 8.2
Geissoschizine 8.1
Mirtazapine 8.0
cyclopropanecarboxamide 8.0
N,N-diethylacetamide 7.9
Prazepam 7.7
Isocarboxazide 7.6
Dormicum 7.6
Gelsemine 7.6
2-phenyl-1,3-propanediol 7.6
Fastin 7.5
Echinocystic acid 7.5
Fleroxacin 7.4
Decursinol 7.2
Nitrazepam 7.2
Bupropion 7.1
Diethylpropion 7.1
Sibutramine 6.8
Quetiapine 6.8
Cadinene 6.7
1-piperidinecarboxamide 6.7
Thiothixene 6.7
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