Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0917801 (insomnia)
10,606 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 650 REM 283 prion 212 orexin 208 GABA 200 CBT 167 prion protein 162 She 108 PrP 98 Mol 89 C30 62 MRI 62 ICD 49 Gen 48 Orexin 46 PRNP 45 insulin 42 GABA(A) receptor 37 hemoglobin 35 dream 35 5-hydroxytryptamine 35 cytokine 35 Pol 34 prolactin 33 CGI 31 beta-endorphin 30 MT2 29 reserved 29 Men 27 MT1 27 interferon 27 CSF 26 cytochrome P450 26 ANOVA 26 5-HT2A 24 ADHD 24 5-HT1A 24 C-reactive protein 23 APA 21 cage 20 more...

Disease depression 2436 sleep disorders 1416 sleep disturbances 875 cancer 449 major depressive disorder 402 sleep apnea 365 restless legs syndrome 354 hypertension 318 obstructive sleep apnea 309 psychosis 307 dementia 288 posttraumatic stress disorder 284 mental illness 276 anxiety disorders 260 narcolepsy 256 schizophrenia 246 Parkinson's disease 223 epilepsy 217 hallucinations 215 Creutzfeldt-Jakob disease 211 diabetes 199 Alzheimer's disease 197 cognitive impairment 192 obesity 190 chronic pain 187 xerostomia 177 suicide 177 Sleep disturbance 169 addiction 136 confusion 131 stroke 123 Gerstmann 120 breast cancer 113 delirium 108 pruritus 103 cardiovascular disease 100 bipolar disorder 100 migraine 95 psychological distress 91 mania 91 more...

Symptom insomnia 10606 sleepiness 1104 fatigue 990 pain 813 headache 779 nausea 499 agitation 433 dizziness 346 anorexia 279 seizures 233 vomiting 219 hypersomnia 216 constipation 199 diarrhea 191 tremor 152 dyspnea 127 weakness 121 snoring 104 discomfort 84 nausea and vomiting 80 ataxia 73 myoclonus 72 hot flushes 68 cough 67 discomfort 65 asthenia 65 tinnitus 64 hot flashes 63 back pain 63 abdominal pain 63 vertigo 63 myalgia 62 decreased appetite 60 Poor sleep 57 menopausal symptoms 56 paresthesia 53 exhaustion 50 arthralgia 49 lethargy 48 anesthesia 45 more...

Drug caffeine 120 Zonisamide 54 Ramelteon 46 Triazolam 37 Spectrum 33 CSF 26 Flurazepam 23 Mirtazapine 23 Dermatol 22 Portal 19 Domperidone 18 Eszopiclone 18 Ambien 18 Duloxetine 18 Cardiovasc 16 Gabapentin 14 Asthma 14 Modafinil 12 Clonidine 11 Monit 11 Leaf 10 Brotizolam 9 Diurnal 9 Moclobemide 9 Lormetazepam 9 Agomelatine 8 Indiplon 8 Dial 8 Pramipexole 8 Donepezil 8 Spectrum 8 Pramipexole 8 ACT 7 Trimipramine 7 Flunitrazepam 7 Atomoxetine 7 Check 7 TAK 6 MT6 6 Paliperidone 6 more...

Enzyme monoamine oxidase 45 acetylcholinesterase 26 ERK 20 alkaline phosphatase 19 alanine aminotransferase 17 CYP3A4 17 aspartate aminotransferase 14 superoxide dismutase 13 catalase 11 cholinesterase 11 reverse transcriptase 10 creatine kinase 10 ACS 9 lactate dehydrogenase 9 proteinase K 9 focal adhesion kinase 9 tryptophan hydroxylase 8 gamma-glutamyl transpeptidase 8 phosphodiesterase 7 adenylate cyclase 7 mitogen-activated protein kinase 7 glutathione peroxidase 6 ATPase 6 thyroid peroxidase 5 protein kinase 5 caspase-3 4 N-acetyltransferase 4 P-glycoprotein 4 renin 4 calcineurin 4 lipase 4 glutathione reductase 4 CPT 4 CPT 4 AOR 4 CPT 4 choline acetyltransferase 4 carbonic anhydrase 3 NO synthase 3 MCS 3 more...

Compound Clin 1279 Dec 703 DSM 245 GABA 207 GABA 202 Melatonin 158 caffeine 120 Zolpidem 119 5-HT 110 ethanol 103 oxygen 98 water 91 sodium 88 gamma-aminobutyric acid 67 tryptophan 65 glucose 65 tryptophan 65 tryptophan 64 tryptophan 64 calcium 63 noradrenaline 61 methionine 60 DNA 45 glutamate 43 His 42 Trazodone 41 iron 40 potassium 37 creatinine 36 Zaleplon 31 Diazepam 30 acetate 29 5-hydroxytryptophan 29 Cardiol 29 Bupropion 27 valine 25 Mirtazapine 23 mercury 23 methanol 22 nitric oxide 20 more...

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