Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917801 (insomnia)
 10,606 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 650
REM 283
prion 212
orexin 208
GABA 200
CBT 167
prion protein 162
She 108
PrP 98
Mol 89
C30 62
MRI 62
ICD 49
Gen 48
Orexin 46
PRNP 45
insulin 42
GABA(A) receptor 37
5-hydroxytryptamine 35
dream 35
more...
Disease
depression 2436
sleep disorders 1416
sleep disturbances 875
cancer 449
major depressive disorder 402
sleep apnea 365
restless legs syndrome 354
hypertension 318
obstructive sleep apnea 309
psychosis 307
dementia 288
posttraumatic stress disorder 284
mental illness 276
anxiety disorders 260
narcolepsy 256
schizophrenia 246
Parkinson's disease 223
epilepsy 217
hallucinations 215
Creutzfeldt-Jakob disease 211
more...
Symptom
insomnia 10606
sleepiness 1104
fatigue 990
pain 813
headache 779
nausea 499
agitation 433
dizziness 346
anorexia 279
seizures 233
vomiting 219
hypersomnia 216
constipation 199
diarrhea 191
tremor 152
dyspnea 127
weakness 121
snoring 104
discomfort 84
nausea and vomiting 80
more...
Drug
caffeine 120
Zonisamide 54
Ramelteon 46
Triazolam 37
Spectrum 33
CSF 26
Mirtazapine 23
Flurazepam 23
Dermatol 22
Portal 19
Eszopiclone 18
Domperidone 18
Ambien 18
Duloxetine 18
Cardiovasc 16
Gabapentin 14
Asthma 14
Modafinil 12
Monit 11
Clonidine 11
more...
Enzyme
monoamine oxidase 45
acetylcholinesterase 26
ERK 20
alkaline phosphatase 19
CYP3A4 17
alanine aminotransferase 17
aspartate aminotransferase 14
superoxide dismutase 13
catalase 11
cholinesterase 11
creatine kinase 10
reverse transcriptase 10
lactate dehydrogenase 9
focal adhesion kinase 9
proteinase K 9
ACS 9
tryptophan hydroxylase 8
gamma-glutamyl transpeptidase 8
phosphodiesterase 7
adenylate cyclase 7
more...
Compound
Clin 1279
Dec 703
DSM 245
GABA 207
GABA 202
Melatonin 158
caffeine 120
Zolpidem 119
5-HT 110
ethanol 103
oxygen 98
water 91
sodium 88
gamma-aminobutyric acid 67
glucose 65
tryptophan 65
tryptophan 65
tryptophan 64
tryptophan 64
calcium 63
more...