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Query: UMLS:C0917801 (insomnia)
 10,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Men and women living contentedly in long-term isolation from the usual time-of-day cues have revealed surprising new regularities about the timing of human sleep/wake alternations. Contemporary effort to ferret out and articulate these regularities in quantitative terms lead to a diversity of mathematical models. If these eventually acquire predictive competence then we may expect practical improvements of therapy for insomnia, jet lag, and some kinds of psychiatric depression.
Am J Physiol 1982 Sep
PMID:Circadian timing of sleepiness in man and woman. 705 61

"Topics in Primary Care Medicine" presents articles on common diagnostic or therapeutic problems (such as dizziness, pruritus, insomnia, shoulder pain and urinary tract infections) encountered in primary care practice that generally do not fall into well-defined subspecialty areas and are rarely discussed thoroughly in medical school, house staff training, textbooks and journals. Often the pathophysiology is poorly understood and clinical trials to assess the effectiveness of diagnostic tests or therapies may be lacking. Nevertheless, these problems confront practitioners with practical management questions. The articles in this series discuss new tests and therapies and suggest reasonable approaches even when definitive studies are not available. Each article has several general references for suggested further reading. We hope this new series will be of interest and we welcome comments, criticisms and suggestions.
West J Med 1982 Sep
PMID:The evaluation of anemia. 714 37

In this preliminary investigation sixteen latency-age children were compared with matched good sleep children from child psychiatric and general pediatric clinic populations. Parent and child reports support the existence of chronic childhood insomnia, occurring at a greater frequency in an emotionally disturbed population. Although parent-child agreement on insomnia symptoms tends to be high, there was poor agreement on other sleep-related symptoms.
Sleep 1981 Sep
PMID:Insomniac children. 730 62

Sleep EEGs of 30 chronic insomnia patients are compared with the patients' subjective estimation of the duration of sleep and the number of waking periods during the night's recording. Overall, the patients overestimated the duration of sleep and, to a lesser degree, the time they awaken in the morning. The number and duration of waking periods in the night were regularly underestimated, and no correlation could be found between the estimated number of waking periods and those actually recorded on the EEG. The composition of sleep on falling asleep and on waking, when these are overestimated, showed an appreciable period of waking sleep at these times (21% and 41% respectively). The authors suggest that their results indicate that study of the transitional periods of sleep and waking may provide a better understanding of insomnia and lead to alternative therapeutic approaches. They also indicate that the shorter duration of sleep is only one aspect of insomnia and other factors are probably important.
Rev Electroencephalogr Neurophysiol Clin 1981 Sep
PMID:[Comparison of the waking EEG with the subjective impressions of the waking individual (author's transl)]. 731 44

The effects upon sleep returning after an effective dose of Tabernanthine p-chlorophenoxyacetate (SAD 103) are studied on chronically implanted cats. The near-total insomnia lasting for 6-8 h provoked by SAD is characterized by a calm waking period broken by periods of drowsiness. Recuperation follows a characteristic pattern: slow-wave sleep first reappears as phasic slow-wave sleep, the duration of the phases augmenting greatly between the 12th and 18th hour, after which slow-wave sleep reappears. After having been blocked for some 10 h, paradoxical sleep is seen again, remaining, however, as does slow-wave sleep, below normal for the first 30 h. The basic mechanisms behind the stimulating effect of SAD 103 are still unknown; hypotheses derived from recent neurophysiological and neurochemical investigations on sleep are discussed.
Rev Electroencephalogr Neurophysiol Clin 1981 Sep
PMID:[Restoration of sleep in cats pretreated with tabernanthine p-chlorophenoxyacetate (SAD 103) (author's transl)]. 731 49

The role and importance of the number of awakenings and their duration in relation to increasing intervening wakefulness were investigated. The data were collected from a group of 38 subjects suffering from chronic primary insomnia, aged 17-70 years, polygraphically recorded; the analysis was made on the second night. With age, the total quantity of intervening wakefulness increases more quickly than the total number of awakenings. The amount of wakefulness due to awakenings lasting greater than or equal to 3 min increases with age. Older insomniacs wake up somewhat more often but, above all, they go back to sleep less quickly. Our hypothesis is that in old patients insomnia is linked to an increase in stability of wakefulness.
Rev Electroencephalogr Neurophysiol Clin 1981 Sep
PMID:[Age and insomnia: the number and length of waking periods (author's transl)]. 731 62

In this study we attempted to measure the odour immissions objectively and to bring them in relation with the subjective statements of the population. As measure of odour intensity, merely the distance from the source of emission could be considered. A self-rating thermometer as well as subjective complaints, such as sleeplessness, nausea and the intention to move, permitted us to derive distinct annoyance levels at various distances from the source.
Soz Praventivmed 1980 Sep
PMID:[Annoyance by odors]. 745 33

In a representative selection of German citizens who were older than 13 years of age, 1,997 were asked about their sleep complaints. They were also asked how frequently a physician was consulted and how often sleeping pills were taken. According to our results sleep disturbances are an important health problem in Germany. Every fourth person suffers at least sometimes from difficulties in falling asleep and/or staying asleep, problems which are not due to external influences. Seven percent suffer frequently or always from these complaints; 15% report that they are frequently tired or that they are always tired during the day. Ten percent of all persons suffering from sleep complaints take sleeping pills daily or at least sometimes during the week. Forty-five percent of all persons who take hypnotics daily still frequently or always suffer from difficulties in falling asleep and/or staying asleep. Furthermore, sleep complaints tend to become chronic: 75% of the sleep-disturbed population are chronically ill, having had complaints for more than 2 years of since childhood. They suffer from sleep disturbances and from reduced performance during the following day. Nevertheless, it appears as though neither patients nor physicians take insomnia seriously. This might answer the question of why only 17% of the persons who do not suffer more than 2 years from sleep disturbances and only 49% of the chronically ill population consult a doctor because of their sleep disturbances. The results of this study indicate the importance of informing patients and physicians about insomnia and different ways of treating it.
Nervenarzt 1995 Sep
PMID:[Chronification of sleep disorders. Results of a representative survey in West Germany]. 747 6

The Hamilton Depression Rating Scale was applied to 60 depressed inpatients diagnosed using the Composite International Diagnostic Interview. The information to rate the scale was obtained with a semistructured interview to standardize the scale administration method. Items were factorized using principal components analysis with Varimax rotation. Three factors were obtained with the simulation method, accounting for 47% of variance. The first includes the core symptoms of depression. The symptoms of patients having an isolated mood disorder were compared with those having comorbidity with other diagnoses. The comorbidity did not affect the first factor but modified the second factor (anxiety) and the third factor (insomnia).
Acta Psychiatr Scand 1995 Sep
PMID:Factorial structure of the 17-item Hamilton Depression Rating Scale. 748 92

This study was conducted to determine whether intravenous theophylline, added to inhaled albuterol and intravenous methylprednisolone, provides a clinically significant benefit in the treatment of pediatric status asthmaticus. Patients aged 2 to 10 years were randomized to receive either intravenous theophylline or placebo. All patients received aerosolized albuterol and intravenous methylprednisolone. There was no difference between groups in the improvement of a clinical asthma score over time, in oxygen requirement, or in the number of albuterol treatments required. Theophylline group patients experienced more nausea, emesis, and insomnia. We conclude that there is no benefit in adding theophylline to treatment with methylprednisolone and albuterol for pediatric status asthmaticus. Furthermore, there are significantly more adverse effects associated with the use of theophylline.
Clin Pediatr (Phila) 1995 Sep
PMID:Intravenous theophylline in pediatric status asthmaticus. A prospective, randomized, double-blind, placebo-controlled trial. 758 20


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