Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917801 (insomnia)
10,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Development of body image is an integral part of a teenager's psychological growth. Burned teenagers experience great difficulty in readjusting psychosocially after injury as they have not yet formed their own self-concept and sense of worth. Burns patients experience a range of psychological problems as a consequence of disfigurement. These include depression, phobias, insomnia, sexual problems, high divorce rates, juvenile delinquency and impaired employment or academic status. Few nursing research articles have addressed the psychosocial problems of burns patients. Even if nurses are not skilled in counselling they must be able to recognize problems and refer patients to colleagues with the appropriate skills.
...
PMID:Nursing a teenager with burns. 848 60

Attention-deficit-hyperactivity disorder (ADHD) is a common neuropsychiatric disorder that impairs social, academic, and occupational functioning in children, adolescents, and adults. In patients with ADHD, neurobiologic research has shown a lack of connectivity in key brain regions, inhibitory control deficits, delayed brain maturation, and noradrenergic and dopaminergic dysfunction in multiple brain regions. The prevalence of this disorder in the United States is 6-9% in youth (i.e., children and adolescents) and 3-5% in adults. Prevalence rates for youth are similar worldwide. Children with ADHD are at greater risk than children without ADHD for substance abuse and delinquency whether or not they receive drug therapy; however, early treatment with psychoeducation as well as drug therapy and/or behavioral intervention may decrease negative outcomes of ADHD, including the rate of conduct disorder and adult antisocial personality disorder. Drug therapy is effective for all age groups, even preschoolers, and for late-onset ADHD in adults. Stimulants, such as methylphenidate and amphetamine, are the most effective therapy and have a good safety profile; although recent concerns of sudden unexplained death, psychiatric adverse effects, and growth effects have prompted the introduction of other therapies. Atomoxetine, a nonstimulant, has no abuse potential, causes less insomnia than stimulants, and poses minimal risk of growth effects. Other drug options include clonidine and guanfacine, but both can cause bradycardia and sedation. Polyunsaturated fatty acids (fish oil), acetyl-L-carnitine, and iron supplements (for youth with low ferritin levels) show promise in improving ADHD symptoms. As long-term studies show that at least 50% of youth are nonadherent with their drug therapy as prescribed over a 1-year period, long-acting formulations (administered once/day) may improve adherence. Comorbid conditions are common in patients with ADHD, but this patient population can be treated effectively with individualized treatment regimens of stimulants, atomoxetine, or bupropion, along with close monitoring.
...
PMID:Attention-deficit-hyperactivity disorder: an update. 1947 19

This study investigated whether previously reported links between sleep and risk taking among adolescents (E. M. O'Brien & J. A. Mindell, 2005) are associated-concurrently, longitudinally, or both-with sleep or underlying depression. The present study analyzed data from a nationally representative sample of 4,353 adolescents in the United States who had participated in Waves I and II of the National Longitudinal Study of Adolescent Health (J. R. Udry, 1998). In the present study, grade, gender, depressive symptoms, and possible insomnia served as predictor variables to calculate the odds ratios for 4 categories of risky behaviors. After the authors accounted for other predictors, possible insomnia significantly predicted smoking, delinquency (within each wave but not longitudinally), and drinking and driving (Wave II and longitudinally). Possible insomnia may contribute to some types of risky behaviors over the effects of depressive symptoms.
...
PMID:Possible insomnia predicts some risky behaviors among adolescents when controlling for depressive symptoms. 2003 86