Gene/Protein
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Pivot Concepts:
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Target Concepts:
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Query: UMLS:C0917801 (
insomnia
)
10,606
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The authors report a case of eosinophilia-myalgia syndrome with a progressive
neuromyopathy
. Progressive weakness, myalgia, and dermatitis developed in the patient described after chronic ingestion of high-dose L-tryptophan for
insomnia
. Laboratory, electrophysiologic, and muscle biopsy results support the diagnosis of an inflammatory myopathy consistent with that of eosinophilia-myalgia syndrome. The patient's weakness led to wheelchair dependency. A review of the literature regarding this disorder shows inconsistent results with steroid and other modes of therapy. After a course of high-dose steroids with long-term tapering and vigorous inpatient and outpatient rehabilitation, the patient was able to walk and function independently within 2 months.
...
PMID:Clinical improvement of the myopathy in eosinophilia-myalgia syndrome with steroids and rehabilitative therapy. 142 67
