Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0917798 (
cerebral ischemia
)
17,036
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CA1
1274
Sep
1081
Mol
876
caspase-3
686
penumbra
501
Bcl-2
412
superoxide dismutase
404
ATP
389
glial fibrillary acidic protein
335
TNF
330
cytokine
322
tumor necrosis factor
299
OGD
289
MRI
275
nitric oxide synthase
261
NMDA receptor
255
inducible nitric oxide synthase
238
CA3
230
brain-derived neurotrophic factor
215
IL-6
200
vascular endothelial growth factor
187
tissue plasminogen activator
184
cytochrome c
182
GSH
172
CBF
171
lactate dehydrogenase
160
endoplasmic reticulum
159
matrix metalloproteinase
159
PI3K
154
axonal
150
catalase
148
MMP-9
143
GABA
142
glutathione peroxidase
137
ERK1
131
hemoglobin
131
p38
117
TLR4
115
insulin
114
glutamate receptor
113
mTOR
112
PLA
111
p53
111
ATPase
110
SOD
110
endothelin-1
109
lipopolysaccharide
108
MAPK
104
JNK
103
p65
102
myeloperoxidase
101
cyclooxygenase-2
100
ERK
99
interleukin-6
97
calpain
97
AKT
92
heme oxygenase-1
92
neuronal nitric oxide synthase
91
calcium channel
90
c-Jun
88
Nrf2
88
AMP
87
albumin
84
NAD
83
ROS
82
HSP70
82
VEGF
82
CSF
81
erythroid
80
occludin
79
amyloid precursor protein
79
MMP-2
78
collagen
77
erythropoietin
77
PARP
77
CA2
76
DCX
75
LC3
75
calmodulin
74
CO2
72
more...
Disease
cerebral ischemia
17036
ischemia
6472
stroke
5386
cerebral infarction
854
subarachnoid hemorrhage
739
brain edema
535
hypertension
534
Alzheimer's disease
459
depression
309
diabetes
288
transient ischemic attack
256
Parkinson's disease
220
cognitive impairment
202
Ischemic stroke
200
epilepsy
197
dementia
194
atherosclerosis
194
cerebral vasospasm
191
hyperglycemia
176
Evans
172
GSH
172
myocardial infarction
169
tumor
154
coma
133
cancer
120
migraine
115
myocardial ischemia
109
memory impairment
107
multiple sclerosis
106
encephalopathy
103
moyamoya
100
Middle cerebral artery occlusion
99
vascular disease
98
hypoglycemia
86
NAME
84
hydrocephalus
82
plaque
82
SEM
78
hemiparesis
74
neuroblastoma
74
Huntington's disease
70
heart failure
68
amyotrophic lateral sclerosis
64
lactic acidosis
61
neurological disease
58
cardiovascular disease
56
carotid artery stenosis
55
intracranial aneurysm
54
systemic lupus erythematosus
52
coronary artery disease
52
cold
50
Transient cerebral ischemia
49
brain atrophy
45
brain dysfunction
44
CNS diseases
44
heart disease
44
vasculitis
41
fits
40
B-cell lymphoma
40
anemia
39
sepsis
38
pheochromocytoma
38
amnesia
37
Transient ischemia
37
sepsis
37
meningitis
36
cerebral embolism
35
obesity
35
status epilepticus
34
schizophrenia
34
antiphospholipid syndrome
31
lupus
31
ventricular fibrillation
31
cerebral aneurysm
30
aphasia
30
arteriosclerosis
30
acute myocardial infarction
29
coronary heart disease
29
hyperlipidemia
29
Blocking
28
more...
Symptom
anesthesia
383
hypothermia
381
functional recovery
357
seizures
342
headache
133
pain
104
hypercapnia
78
spasm
53
hemiplegia
45
hypocapnia
38
syncope
37
angina
36
collapse
35
hyperoxia
34
weakness
30
dizziness
25
vertigo
20
neurological disability
20
paresis
15
analgesia
14
memory loss
14
dysarthria
14
dyspnea
13
fatigue
13
exhaustion
13
tremor
13
nausea
11
chorea
11
vomiting
11
cough
11
neck pain
10
respiratory distress
9
incoordination
9
ataxia
9
sleepiness
8
tinnitus
8
insomnia
8
livedo
7
myoclonus
7
chest pain
7
lethargy
7
starvation
7
spasticity
7
numbness
6
discomfort
6
discomfort
6
agitation
6
blurred vision
5
pallor
5
hoarseness
5
nausea and vomiting
5
back pain
4
paraparesis
4
dystonia
4
despair
4
Induced hypothermia
4
acute stress
4
Anoxia
4
bradykinesia
3
thinning
3
Ill
3
abdominal pain
3
sinus pressure
3
ophthalmoplegia
3
diarrhea
3
Amaurosis fugax
3
Sedation
3
asthenia
3
paresthesia
3
tonic-clonic seizure
3
impaired motor coordination
2
flushing
2
lightheadedness
2
Neurologic symptoms
2
facial droop
2
facial pain
2
exertional angina
2
ENT
2
snoring
2
Central post-stroke pain
2
more...
Drug
TTC
137
Cardiovasc
118
CSF
83
ROS
82
NADH
50
Monit
46
MAP
39
ascorbate
37
lysine
33
vitamin E
33
Propofol
25
TAT
23
EE2
22
Nitric Oxide
21
Indomethacin
20
Heme
16
Ringer's solution
14
caffeine
14
CPR
14
Estrogens
14
G-CSF
14
ICI
12
Cilostazol
12
p75
12
Albumin
11
MgSO4
11
Ginseng
10
IL-2
10
Rosiglitazone
10
Phenytoin
10
nitroglycerin
10
Ethanol
10
Portal
10
IFN-gamma
10
ETA
10
Parkin
9
IL-1ra
9
Parkin
9
Clopidogrel
9
Histamine
9
Glucagon
9
Glutathione
8
Nephron
8
Angiotensin II
8
CTX
8
TAK
8
Clonidine
7
Rolipram
7
ROC
7
Vitamin E
7
Tacrolimus
7
EPI
7
Diamox
7
Gel
6
Adenosine triphosphate
6
Cytidine
6
FAD
6
Simvastatin
6
Fluorescein
6
Aminoguanidine
6
7-Nitroindazole
6
DPA
6
Magnesium sulfate
6
Vinpocetine
6
uPA
6
Gelatin
6
CoCl2
5
Propentofylline
5
Tirilazad mesylate
5
CoCl2
5
Tirilazad mesylate
5
citric acid
5
Lubeluzole
5
Glycerol
5
Nilvadipine
5
Ulinastatin
5
Bumetanide
5
CaCl2
5
CaCl2
5
Safflower
5
more...
Enzyme
caspase-3
552
superoxide dismutase
487
mitogen-activated protein kinase
419
tissue plasminogen activator
245
protein kinase
215
catalase
165
lactate dehydrogenase
163
glutathione peroxidase
141
ERK
136
peroxidase
135
NO synthase
134
ATPase
122
protein kinase C
109
PARP
104
luciferase
81
MEK
73
NADPH oxidase
72
NOS
71
thrombin
69
NADPH oxidase
66
GSK
63
AMP-activated protein kinase
60
caspase-9
54
focal adhesion kinase
52
caspase-1
49
xanthine oxidase
48
phosphodiesterase
47
proteasome
45
phospholipase A2
44
phosphatidylinositol 3-kinase
44
creatine kinase
41
AMPK
40
calcineurin
38
CaMKII
37
acetylcholinesterase
34
thromboplastin
33
AMPK
33
glutathione reductase
32
urokinase-type plasminogen activator
32
ACS
32
succinate dehydrogenase
31
heme oxygenase
30
ornithine decarboxylase
28
reverse transcriptase
27
renin
26
lipoxygenase
26
collagenase
26
complex I
25
cathepsin B
25
choline acetyltransferase
25
tyrosine hydroxylase
24
cytochrome oxidase
24
TdT
24
TAT
23
APC
23
phospholipase C
22
NQO1
21
plasmin
21
pyruvate dehydrogenase
20
enolase
20
caspase-8
20
glutamine synthetase
20
MMP
19
MAP
18
ACE
18
glutathione S-transferase
18
matrix metalloproteinase 9
18
aspartate aminotransferase
17
IKK
17
adenylate cyclase
16
CPR
16
phosphoinositide 3-kinase
16
kallikrein
16
pyruvate dehydrogenase
14
pyruvate dehydrogenase
14
alanine aminotransferase
13
peroxiredoxin
12
cathepsin D
12
alkaline phosphatase
12
MIP
11
more...
Compound
oxygen
2203
glucose
1517
Dec
1223
glutamate
940
calcium
923
water
923
Cereb
866
nitric oxide
545
Clin
524
DNA
470
sodium
434
ATP
389
TNF
330
NMDA
250
Neuronal
227
hydrogen
219
dUTP
207
potassium
191
GSH
177
GSH
177
arginine
171
phosphate
161
TTC
156
GABA
145
GABA
144
MCA
136
MCA
136
CO2
135
iron
123
AMPA
103
Glutamate
103
phosphocreatine
100
NAD
97
zinc
96
serine
94
AMP
94
Cardiol
89
tyrosine
89
ADP
84
NAD
83
nitrogen
83
MDA
79
gamma-aminobutyric acid
79
fluorine
78
galactose
74
Nimodipine
73
H2O2
73
cysteine
69
ADP
69
ADP
68
MTT
68
nicotinamide
65
iodine
62
prostacyclin
61
5-HT
54
ethanol
54
acetate
54
alanine
54
Asp
52
ASA
50
NADH
50
ADP-ribose
50
cAMP
48
Evans Blue
46
salt
45
glycerol
45
noradrenaline
45
FK506
44
Melatonin
43
His
42
8-OHdG
42
DMSO
42
S-adenosylhomocysteine
41
copper
41
aspartic acid
41
PEG
40
glutamine
40
Resveratrol
40
sulfate
40
nitrate
40
more...