Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917798 (cerebral ischemia)
17,036 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CA1 1274
Sep 1081
Mol 876
caspase-3 686
penumbra 501
Bcl-2 412
superoxide dismutase 404
ATP 389
glial fibrillary acidic protein 335
TNF 330
cytokine 322
tumor necrosis factor 299
OGD 289
MRI 275
nitric oxide synthase 261
NMDA receptor 255
inducible nitric oxide synthase 238
CA3 230
brain-derived neurotrophic factor 215
IL-6 200
vascular endothelial growth factor 187
tissue plasminogen activator 184
cytochrome c 182
GSH 172
CBF 171
lactate dehydrogenase 160
endoplasmic reticulum 159
matrix metalloproteinase 159
PI3K 154
axonal 150
catalase 148
MMP-9 143
GABA 142
glutathione peroxidase 137
ERK1 131
hemoglobin 131
p38 117
TLR4 115
insulin 114
glutamate receptor 113
mTOR 112
PLA 111
p53 111
ATPase 110
SOD 110
endothelin-1 109
lipopolysaccharide 108
MAPK 104
JNK 103
p65 102
myeloperoxidase 101
cyclooxygenase-2 100
ERK 99
interleukin-6 97
calpain 97
AKT 92
heme oxygenase-1 92
neuronal nitric oxide synthase 91
calcium channel 90
c-Jun 88
Nrf2 88
AMP 87
albumin 84
NAD 83
ROS 82
HSP70 82
VEGF 82
CSF 81
erythroid 80
occludin 79
amyloid precursor protein 79
MMP-2 78
collagen 77
erythropoietin 77
PARP 77
CA2 76
DCX 75
LC3 75
calmodulin 74
CO2 72
more...
Disease
cerebral ischemia 17036
ischemia 6472
stroke 5386
cerebral infarction 854
subarachnoid hemorrhage 739
brain edema 535
hypertension 534
Alzheimer's disease 459
depression 309
diabetes 288
transient ischemic attack 256
Parkinson's disease 220
cognitive impairment 202
Ischemic stroke 200
epilepsy 197
dementia 194
atherosclerosis 194
cerebral vasospasm 191
hyperglycemia 176
Evans 172
GSH 172
myocardial infarction 169
tumor 154
coma 133
cancer 120
migraine 115
myocardial ischemia 109
memory impairment 107
multiple sclerosis 106
encephalopathy 103
moyamoya 100
Middle cerebral artery occlusion 99
vascular disease 98
hypoglycemia 86
NAME 84
hydrocephalus 82
plaque 82
SEM 78
hemiparesis 74
neuroblastoma 74
Huntington's disease 70
heart failure 68
amyotrophic lateral sclerosis 64
lactic acidosis 61
neurological disease 58
cardiovascular disease 56
carotid artery stenosis 55
intracranial aneurysm 54
systemic lupus erythematosus 52
coronary artery disease 52
cold 50
Transient cerebral ischemia 49
brain atrophy 45
brain dysfunction 44
CNS diseases 44
heart disease 44
vasculitis 41
fits 40
B-cell lymphoma 40
anemia 39
sepsis 38
pheochromocytoma 38
amnesia 37
Transient ischemia 37
sepsis 37
meningitis 36
cerebral embolism 35
obesity 35
status epilepticus 34
schizophrenia 34
antiphospholipid syndrome 31
lupus 31
ventricular fibrillation 31
cerebral aneurysm 30
aphasia 30
arteriosclerosis 30
acute myocardial infarction 29
coronary heart disease 29
hyperlipidemia 29
Blocking 28
more...
Symptom
anesthesia 383
hypothermia 381
functional recovery 357
seizures 342
headache 133
pain 104
hypercapnia 78
spasm 53
hemiplegia 45
hypocapnia 38
syncope 37
angina 36
collapse 35
hyperoxia 34
weakness 30
dizziness 25
vertigo 20
neurological disability 20
paresis 15
analgesia 14
memory loss 14
dysarthria 14
dyspnea 13
fatigue 13
exhaustion 13
tremor 13
nausea 11
chorea 11
vomiting 11
cough 11
neck pain 10
respiratory distress 9
incoordination 9
ataxia 9
sleepiness 8
tinnitus 8
insomnia 8
livedo 7
myoclonus 7
chest pain 7
lethargy 7
starvation 7
spasticity 7
numbness 6
discomfort 6
discomfort 6
agitation 6
blurred vision 5
pallor 5
hoarseness 5
nausea and vomiting 5
back pain 4
paraparesis 4
dystonia 4
despair 4
Induced hypothermia 4
acute stress 4
Anoxia 4
bradykinesia 3
thinning 3
Ill 3
abdominal pain 3
sinus pressure 3
ophthalmoplegia 3
diarrhea 3
Amaurosis fugax 3
Sedation 3
asthenia 3
paresthesia 3
tonic-clonic seizure 3
impaired motor coordination 2
flushing 2
lightheadedness 2
Neurologic symptoms 2
facial droop 2
facial pain 2
exertional angina 2
ENT 2
snoring 2
Central post-stroke pain 2
more...
Drug
TTC 137
Cardiovasc 118
CSF 83
ROS 82
NADH 50
Monit 46
MAP 39
ascorbate 37
lysine 33
vitamin E 33
Propofol 25
TAT 23
EE2 22
Nitric Oxide 21
Indomethacin 20
Heme 16
Ringer's solution 14
caffeine 14
CPR 14
Estrogens 14
G-CSF 14
ICI 12
Cilostazol 12
p75 12
Albumin 11
MgSO4 11
Ginseng 10
IL-2 10
Rosiglitazone 10
Phenytoin 10
nitroglycerin 10
Ethanol 10
Portal 10
IFN-gamma 10
ETA 10
Parkin 9
IL-1ra 9
Parkin 9
Clopidogrel 9
Histamine 9
Glucagon 9
Glutathione 8
Nephron 8
Angiotensin II 8
CTX 8
TAK 8
Clonidine 7
Rolipram 7
ROC 7
Vitamin E 7
Tacrolimus 7
EPI 7
Diamox 7
Gel 6
Adenosine triphosphate 6
Cytidine 6
FAD 6
Simvastatin 6
Fluorescein 6
Aminoguanidine 6
7-Nitroindazole 6
DPA 6
Magnesium sulfate 6
Vinpocetine 6
uPA 6
Gelatin 6
CoCl2 5
Propentofylline 5
Tirilazad mesylate 5
CoCl2 5
Tirilazad mesylate 5
citric acid 5
Lubeluzole 5
Glycerol 5
Nilvadipine 5
Ulinastatin 5
Bumetanide 5
CaCl2 5
CaCl2 5
Safflower 5
more...
Enzyme
caspase-3 552
superoxide dismutase 487
mitogen-activated protein kinase 419
tissue plasminogen activator 245
protein kinase 215
catalase 165
lactate dehydrogenase 163
glutathione peroxidase 141
ERK 136
peroxidase 135
NO synthase 134
ATPase 122
protein kinase C 109
PARP 104
luciferase 81
MEK 73
NADPH oxidase 72
NOS 71
thrombin 69
NADPH oxidase 66
GSK 63
AMP-activated protein kinase 60
caspase-9 54
focal adhesion kinase 52
caspase-1 49
xanthine oxidase 48
phosphodiesterase 47
proteasome 45
phospholipase A2 44
phosphatidylinositol 3-kinase 44
creatine kinase 41
AMPK 40
calcineurin 38
CaMKII 37
acetylcholinesterase 34
thromboplastin 33
AMPK 33
glutathione reductase 32
urokinase-type plasminogen activator 32
ACS 32
succinate dehydrogenase 31
heme oxygenase 30
ornithine decarboxylase 28
reverse transcriptase 27
renin 26
lipoxygenase 26
collagenase 26
complex I 25
cathepsin B 25
choline acetyltransferase 25
tyrosine hydroxylase 24
cytochrome oxidase 24
TdT 24
TAT 23
APC 23
phospholipase C 22
NQO1 21
plasmin 21
pyruvate dehydrogenase 20
enolase 20
caspase-8 20
glutamine synthetase 20
MMP 19
MAP 18
ACE 18
glutathione S-transferase 18
matrix metalloproteinase 9 18
aspartate aminotransferase 17
IKK 17
adenylate cyclase 16
CPR 16
phosphoinositide 3-kinase 16
kallikrein 16
pyruvate dehydrogenase 14
pyruvate dehydrogenase 14
alanine aminotransferase 13
peroxiredoxin 12
cathepsin D 12
alkaline phosphatase 12
MIP 11
more...
Compound
oxygen 2203
glucose 1517
Dec 1223
glutamate 940
calcium 923
water 923
Cereb 866
nitric oxide 545
Clin 524
DNA 470
sodium 434
ATP 389
TNF 330
NMDA 250
Neuronal 227
hydrogen 219
dUTP 207
potassium 191
GSH 177
GSH 177
arginine 171
phosphate 161
TTC 156
GABA 145
GABA 144
MCA 136
MCA 136
CO2 135
iron 123
AMPA 103
Glutamate 103
phosphocreatine 100
NAD 97
zinc 96
serine 94
AMP 94
Cardiol 89
tyrosine 89
ADP 84
NAD 83
nitrogen 83
MDA 79
gamma-aminobutyric acid 79
fluorine 78
galactose 74
Nimodipine 73
H2O2 73
cysteine 69
ADP 69
ADP 68
MTT 68
nicotinamide 65
iodine 62
prostacyclin 61
5-HT 54
ethanol 54
acetate 54
alanine 54
Asp 52
ASA 50
NADH 50
ADP-ribose 50
cAMP 48
Evans Blue 46
salt 45
glycerol 45
noradrenaline 45
FK506 44
Melatonin 43
His 42
8-OHdG 42
DMSO 42
S-adenosylhomocysteine 41
copper 41
aspartic acid 41
PEG 40
glutamine 40
Resveratrol 40
sulfate 40
nitrate 40
more...