Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917798 (cerebral ischemia)
 17,036 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CA1 1274
Sep 1081
Mol 876
caspase-3 686
penumbra 501
Bcl-2 412
superoxide dismutase 404
ATP 389
glial fibrillary acidic protein 335
TNF 330
cytokine 322
tumor necrosis factor 299
OGD 289
MRI 275
nitric oxide synthase 261
NMDA receptor 255
inducible nitric oxide synthase 238
CA3 230
brain-derived neurotrophic factor 215
IL-6 200
vascular endothelial growth factor 187
tissue plasminogen activator 184
cytochrome c 182
GSH 172
CBF 171
lactate dehydrogenase 160
matrix metalloproteinase 159
endoplasmic reticulum 159
PI3K 154
axonal 150
catalase 148
MMP-9 143
GABA 142
glutathione peroxidase 137
hemoglobin 131
ERK1 131
p38 117
TLR4 115
insulin 114
glutamate receptor 113
mTOR 112
p53 111
PLA 111
ATPase 110
SOD 110
endothelin-1 109
lipopolysaccharide 108
MAPK 104
JNK 103
p65 102
myeloperoxidase 101
cyclooxygenase-2 100
ERK 99
interleukin-6 97
calpain 97
heme oxygenase-1 92
AKT 92
neuronal nitric oxide synthase 91
calcium channel 90
Nrf2 88
c-Jun 88
AMP 87
albumin 84
NAD 83
ROS 82
HSP70 82
VEGF 82
CSF 81
erythroid 80
amyloid precursor protein 79
occludin 79
MMP-2 78
erythropoietin 77
PARP 77
collagen 77
CA2 76
DCX 75
LC3 75
calmodulin 74
IL-10 72
CO2 72
caspase-9 72
NMR 71
thrombin 70
COX-2 70
ADP 68
heat shock protein 67
neurotrophic factor 67
c-fos 66
cyclooxygenase 66
LDH 63
nerve growth factor 62
TNF-alpha 62
bcl-2 59
microtubule-associated protein 57
extracellular signal-regulated kinase 57
ubiquitin 57
GSK 56
microtubule-associated protein 2 55
IL-1 55
protein kinase B 54
chemokine 54
endothelial nitric oxide synthase 53
CREB 53
Rho 52
fibrinogen 52
NR2B 50
xanthine oxidase 50
NADH 50
nestin 49
HO-1 49
antioxidant enzyme 48
phosphodiesterase 47
ICAM-1 47
olfactory 47
poly(ADP-ribose) polymerase 47
Beclin-1 46
Iba1 45
p62 45
proteasome 45
phosphatidylinositol 3-kinase 44
glycoprotein 44
cytochrome 43
estrogen receptor 43
TdT 43
STAT3 43
phosphatase 43
SOD1 42
serum albumin 42
CD11b 41
Vascular endothelial growth factor 40
adhesion molecule 40
FK506 40
tumor necrosis factor alpha 40
glutamate transporter 40
PARP-1 39
SAH 39
aquaporin-4 39
MMP9 39
myelin basic protein 38
mitogen-activated protein 38
vascular endothelium 37
ZO-1 37
von Willebrand factor 37
apoptosis-inducing factor 37
parvalbumin 37
PKC 37
CA4 36
synaptophysin 36
PBS 36
intercellular adhesion molecule-1 36
Fas 36
TLR2 35
eNOS 35
angiotensin II 34
urokinase-type plasminogen activator 34
PSD-95 34
GRP78 34
GLT-1 34
catenin 34
more...
Disease
cerebral ischemia 17036
ischemia 6472
stroke 5386
cerebral infarction 854
subarachnoid hemorrhage 739
brain edema 535
hypertension 534
Alzheimer's disease 459
depression 309
diabetes 288
transient ischemic attack 256
Parkinson's disease 220
cognitive impairment 202
Ischemic stroke 200
epilepsy 197
dementia 194
atherosclerosis 194
cerebral vasospasm 191
hyperglycemia 176
GSH 172
Evans 172
myocardial infarction 169
tumor 154
coma 133
cancer 120
migraine 115
myocardial ischemia 109
memory impairment 107
multiple sclerosis 106
encephalopathy 103
moyamoya 100
Middle cerebral artery occlusion 99
vascular disease 98
hypoglycemia 86
NAME 84
hydrocephalus 82
plaque 82
SEM 78
hemiparesis 74
neuroblastoma 74
Huntington's disease 70
heart failure 68
amyotrophic lateral sclerosis 64
lactic acidosis 61
neurological disease 58
cardiovascular disease 56
carotid artery stenosis 55
intracranial aneurysm 54
coronary artery disease 52
systemic lupus erythematosus 52
cold 50
Transient cerebral ischemia 49
brain atrophy 45
brain dysfunction 44
heart disease 44
CNS diseases 44
vasculitis 41
fits 40
B-cell lymphoma 40
anemia 39
pheochromocytoma 38
sepsis 38
sepsis 37
amnesia 37
Transient ischemia 37
meningitis 36
cerebral embolism 35
obesity 35
schizophrenia 34
status epilepticus 34
ventricular fibrillation 31
antiphospholipid syndrome 31
lupus 31
aphasia 30
arteriosclerosis 30
cerebral aneurysm 30
acute myocardial infarction 29
coronary heart disease 29
hyperlipidemia 29
ruptured aneurysm 28
Blocking 28
ICP 28
amaurosis 28
mitral valve prolapse 27
type 2 diabetes 27
raised intracranial pressure 26
lupus 26
confusion 26
renal failure 26
DWI 26
glioma 26
MRS 25
hypercholesterolemia 25
dysplasia 23
EDA 22
Pineal 22
infectious diseases 21
encephalomyelitis 21
carotid disease 21
Takayasu 20
deep vein thrombosis 20
congestive heart failure 20
cerebrovascular insufficiency 20
HIV 20
pneumonia 19
NOD 19
cerebrovascular occlusion 19
pulmonary edema 19
herpes simplex 18
cerebral palsy 18
encephalitis 18
pulmonary embolism 18
ATM 18
endocarditis 18
arteriopathy 17
thrombocytopenia 17
blindness 17
Acute Stroke 17
HSP 17
MAC 17
Horner's syndrome 17
bacterial meningitis 16
fluid overload 16
cerebral thrombosis 16
preeclampsia 16
eclampsia 16
TCD 16
psychosis 16
immunodeficiency 15
cardiomyopathy 15
rind 15
arteriovenous malformation 15
leukemia 15
leukoencephalopathy 15
rheumatoid arthritis 15
brain tumor 15
sleep apnea 15
neuropathy 14
cognitive deficit 14
tumor growth 14
vertebrobasilar insufficiency 13
renal disease 13
parkinsonism 13
pulmonary hypertension 13
coagulopathy 13
metabolic syndrome 13
transient global amnesia 13
Pituitary 13
peripheral vascular disease 13
subclavian steal syndrome 13
Infection 12
dehydration 12
neutropenia 12
unstable angina 12
Vascular dementia 12
arthritis 12
sickle cell disease 12
dissecting aneurysm 12
suicide 12
glaucoma 12
more...
Symptom
anesthesia 383
hypothermia 381
functional recovery 357
seizures 342
headache 133
pain 104
hypercapnia 78
spasm 53
hemiplegia 45
hypocapnia 38
syncope 37
angina 36
collapse 35
hyperoxia 34
weakness 30
dizziness 25
vertigo 20
neurological disability 20
paresis 15
memory loss 14
analgesia 14
dysarthria 14
dyspnea 13
fatigue 13
tremor 13
exhaustion 13
nausea 11
cough 11
chorea 11
vomiting 11
neck pain 10
incoordination 9
ataxia 9
respiratory distress 9
sleepiness 8
insomnia 8
tinnitus 8
chest pain 7
myoclonus 7
lethargy 7
livedo 7
starvation 7
spasticity 7
numbness 6
discomfort 6
discomfort 6
agitation 6
blurred vision 5
hoarseness 5
pallor 5
nausea and vomiting 5
back pain 4
paraparesis 4
Induced hypothermia 4
despair 4
dystonia 4
acute stress 4
Anoxia 4
Sedation 3
Ill 3
thinning 3
abdominal pain 3
diarrhea 3
sinus pressure 3
ophthalmoplegia 3
Amaurosis fugax 3
bradykinesia 3
asthenia 3
paresthesia 3
tonic-clonic seizure 3
overweight 2
Neurologic symptoms 2
exertional angina 2
ENT 2
snoring 2
photophobia 2
Central post-stroke pain 2
exertional dyspnea 2
cyanosis 2
twitching 2
anorexia 2
dysesthesia 2
facial droop 2
facial pain 2
flushing 2
acidity 2
impaired motor coordination 2
lightheadedness 2
blackout 2
arm weakness 2
regurgitation 2
breath holding 2
intestinal angina 1
HSA 1
neck stiffness 1
personality change 1
Severe pain 1
hypoproteinemia 1
eds 1
menopausal symptoms 1
epigastric pain 1
meningism 1
Visual disturbances 1
shoulder pain 1
cachexia 1
catatonia 1
orthopnea 1
Neuropathic pain 1
monoplegia 1
arm pain 1
CSR 1
Gastrointestinal symptoms 1
oliguria 1
clonus 1
general problem 1
Decreased activity 1
splenomegaly 1
lassitude 1
clubbing 1
stridor 1
DNA marker 1
erythema 1
Todd's paralysis 1
Postpartum headache 1
presyncope 1
Regurgitation 1
Multiple symptoms 1
loss of balance 1
Subjective tinnitus 1
fasciculation 1
arthralgia 1
Wind 1
bradypnea 1
Hudson 1
Objective tinnitus 1
clumsiness 1
stigma 1
excessive urination 1
hemoptysis 1
hemiparesthesia 1
hepatomegaly 1
polyuria 1
athetosis 1
myalgia 1
Drug
TTC 137
Cardiovasc 118
CSF 83
ROS 82
NADH 50
Monit 46
MAP 39
ascorbate 37
vitamin E 33
lysine 33
Propofol 25
TAT 23
EE2 22
Nitric Oxide 21
Indomethacin 20
Heme 16
Ringer's solution 14
Estrogens 14
caffeine 14
G-CSF 14
CPR 14
p75 12
Cilostazol 12
ICI 12
MgSO4 11
Albumin 11
Rosiglitazone 10
Ethanol 10
Phenytoin 10
Portal 10
IFN-gamma 10
ETA 10
Ginseng 10
nitroglycerin 10
IL-2 10
Parkin 9
IL-1ra 9
Parkin 9
Clopidogrel 9
Glucagon 9
Histamine 9
Glutathione 8
TAK 8
Nephron 8
CTX 8
Angiotensin II 8
Vitamin E 7
Rolipram 7
ROC 7
EPI 7
Tacrolimus 7
Diamox 7
Clonidine 7
Magnesium sulfate 6
Aminoguanidine 6
FAD 6
Simvastatin 6
7-Nitroindazole 6
DPA 6
uPA 6
Fluorescein 6
Gelatin 6
Vinpocetine 6
Cytidine 6
Gel 6
Adenosine triphosphate 6
Ulinastatin 5
Methylene blue 5
Propentofylline 5
citric acid 5
Bumetanide 5
Tirilazad mesylate 5
CaCl2 5
CaCl2 5
Lubeluzole 5
CoCl2 5
CoCl2 5
Tirilazad mesylate 5
Donepezil 5
Leaf 5
Safflower 5
CaCl2 5
Glycerol 5
Nilvadipine 5
PFT 4
Tao 4
Parecoxib 4
3-Methyladenine 4
Amiloride 4
Atipamezole 4
Alteplase 4
Alteplase 4
Cerestat 4
PCP 4
Nimesulide 4
Idebenone 4
Activin 4
Asn 4
DHT 4
CTA 4
Dial 4
FeCl3 4
Amiloride 4
Alteplase 4
Emodin 4
ABC 4
Rutin 3
Spectrum 3
niacin 3
Fentanyl 3
Iloprost 3
Liraglutide 3
Emodin 3
Forskolin 3
Lovastatin 3
FLP 3
Domperidone 3
Propidium 3
Cantor 3
Fructose 3
Retinoic acid 3
Glycyrrhiza 3
CIA 3
Tianma 3
Glutamic acid 3
Atropine 3
RSM 3
Doxycycline 3
Ozagrel 3
Argatroban 3
Rosuvastatin 3
RFP 3
Hyaluronidase 2
Platelet Activating Factor 2
Bosentan 2
Dextrose 2
Indapamide 2
Kainic acid 2
Indapamide 2
Hydroxyethylstarch 2
Spectrum 2
Epoetin 2
Naftidrofuryl 2
Streptokinase 2
Isradipine 2
Urokinase 2
Pravastatin 2
Thiopentone 2
Bexarotene 2
Ziconotide 2
9-THC 2
Frontal 2
ETS 2
Aliskiren 2
NovoSeven 2
KCL 2
Hyaluronidase 2
Beraprost 2
DHT 2
Fasudil hydrochloride 2
more...
Enzyme
caspase-3 552
superoxide dismutase 487
mitogen-activated protein kinase 419
tissue plasminogen activator 245
protein kinase 215
catalase 165
lactate dehydrogenase 163
glutathione peroxidase 141
ERK 136
peroxidase 135
NO synthase 134
ATPase 122
protein kinase C 109
PARP 104
luciferase 81
MEK 73
NADPH oxidase 72
NOS 71
thrombin 69
NADPH oxidase 66
GSK 63
AMP-activated protein kinase 60
caspase-9 54
focal adhesion kinase 52
caspase-1 49
xanthine oxidase 48
phosphodiesterase 47
proteasome 45
phosphatidylinositol 3-kinase 44
phospholipase A2 44
creatine kinase 41
AMPK 40
calcineurin 38
CaMKII 37
acetylcholinesterase 34
thromboplastin 33
AMPK 33
glutathione reductase 32
urokinase-type plasminogen activator 32
ACS 32
succinate dehydrogenase 31
heme oxygenase 30
ornithine decarboxylase 28
reverse transcriptase 27
collagenase 26
renin 26
lipoxygenase 26
choline acetyltransferase 25
cathepsin B 25
complex I 25
TdT 24
tyrosine hydroxylase 24
cytochrome oxidase 24
TAT 23
APC 23
phospholipase C 22
NQO1 21
plasmin 21
enolase 20
pyruvate dehydrogenase 20
glutamine synthetase 20
caspase-8 20
MMP 19
glutathione S-transferase 18
matrix metalloproteinase 9 18
ACE 18
MAP 18
IKK 17
aspartate aminotransferase 17
kallikrein 16
CPR 16
adenylate cyclase 16
phosphoinositide 3-kinase 16
pyruvate dehydrogenase 14
pyruvate dehydrogenase 14
alanine aminotransferase 13
cathepsin D 12
peroxiredoxin 12
alkaline phosphatase 12
NADPH-diaphorase 11
MIP 11
MMP-3 11
succinic dehydrogenase 10
monoamine oxidase 10
tissue kallikrein 10
guanylate cyclase 10
P-glycoprotein 10
prolyl hydroxylase 9
glucose-6-phosphate dehydrogenase 9
RNA polymerase 9
cholinesterase 9
adenosine deaminase 9
protein phosphatase 2A 9
adenosine deaminase 9
matrix metalloproteinase 2 9
beta-secretase 8
methylenetetrahydrofolate reductase 8
diaphorase 8
methylenetetrahydrofolate reductase 8
PDK1 8
glutamate decarboxylase 8
glyceraldehyde-3-phosphate dehydrogenase 7
endonuclease 7
DNA polymerase 7
PDE 7
lipase 7
transcriptase 7
glyceraldehyde-3-phosphate dehydrogenase 7
MEKK1 7
gamma-glutamylcysteine synthetase 7
Omi/HtrA2 7
soluble epoxide hydrolase 6
glyceraldehyde-3-phosphate dehydrogenase 6
TACE 6
thymidine kinase 6
mu-calpain 6
glutamate dehydrogenase 6
CAD 6
glyceraldehyde-3-phosphate dehydrogenase 6
CD10 6
CAD 6
CAD 6
MPP 6
AST 6
glyceraldehyde-3-phosphate dehydrogenase 6
carbonic anhydrase 5
isocitrate dehydrogenase 5
adenosine kinase 5
aldehyde dehydrogenase 5
m-calpain 5
PKG 5
aldehyde dehydrogenase 5
arginine decarboxylase 5
xanthine dehydrogenase 5
aldehyde dehydrogenase 5
glutamate dehydrogenase 5
glutamate dehydrogenase 5
arginine decarboxylase 5
cdc2 5
aldehyde dehydrogenase 5
aldehyde dehydrogenase 5
firefly luciferase 5
RNase 5
hexokinase 4
isocitrate dehydrogenase 4
ancrod 4
ATP synthase 4
NADH dehydrogenase 4
15-lipoxygenase 4
malate dehydrogenase 4
calcium pump 4
lipoprotein lipase 4
caspase-2 4
3-hydroxy-3-methylglutaryl coenzyme A reductase 4
elastase 4
neutrophil elastase 4
beta-galactosidase 4
ceruloplasmin 4
paraoxonase 4
transglutaminase 4
more...
Compound
oxygen 2203
glucose 1517
Dec 1223
glutamate 940
calcium 923
water 923
Cereb 866
nitric oxide 545
Clin 524
DNA 470
sodium 434
ATP 389
TNF 330
NMDA 250
Neuronal 227
hydrogen 219
dUTP 207
potassium 191
GSH 177
GSH 177
arginine 171
phosphate 161
TTC 156
GABA 145
GABA 144
MCA 136
MCA 136
CO2 135
iron 123
Glutamate 103
AMPA 103
phosphocreatine 100
NAD 97
zinc 96
AMP 94
serine 94
tyrosine 89
Cardiol 89
ADP 84
nitrogen 83
NAD 83
gamma-aminobutyric acid 79
MDA 79
fluorine 78
galactose 74
H2O2 73
Nimodipine 73
cysteine 69
ADP 69
ADP 68
MTT 68
nicotinamide 65
iodine 62
prostacyclin 61
5-HT 54
ethanol 54
acetate 54
alanine 54
Asp 52
NADH 50
ASA 50
ADP-ribose 50
cAMP 48
Evans Blue 46
glycerol 45
salt 45
noradrenaline 45
FK506 44
Melatonin 43
His 42
DMSO 42
8-OHdG 42
aspartic acid 41
S-adenosylhomocysteine 41
copper 41
PEG 40
sulfate 40
Resveratrol 40
glutamine 40
nitrate 40
NBQX 40
threonine 40
SAH 39
bromide 39
leucine 39
lysine 38
MK801 37
Lactate 37
Mg2+ 36
Adenosine 36
glutamic acid 35
cGMP 34
Phe 34
Hematoxylin 33
N2O 32
ACS 32
H2S 32
ACS 32
TEM 31
superoxide radical 31
Sodium 30
silver 30
Minocycline 30
isoxazole 30
Edaravone 29
methionine 29
PGE2 29
Dopamine 29
MEK 28
Gly 26
Naloxone 26
Estradiol 26
Estrogen 26
homocysteine 26
Propofol 26
acetic acid 25
PEG 25
Estrogen 25
propionic acid 25
propionic acid 25
PGE 25
DTPA 25
Salt 24
Curcumin 24
aspartic acid 24
phosphorus 23
manganese 23
Dexmedetomidine 23
GMP 23
N-acetylaspartate 22
CPP 22
CPP 22
CAT 21
CAT 21
CAT 21
tryptophan 21
Baicalin 21
N-acetylcysteine 21
Progesterone 21
tryptophan 20
MAP 20
tryptophan 20
2-nonenal 20
uridine 20
Angiotensin II 20
tryptophan 20
Quercetin 19
Puerarin 19
Cyt 19
NADPH 19
pyrrolidine 19
pyrrolidine 19
NADPH 19
aspartic acid 18
Pentobarbital 18
NO3 18
pyrimidine 18
5-methylisoxazole 18
Rapamycin 18
aspartic acid 18
more...