Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917798 (cerebral ischemia)
 17,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mood disorders associated with stroke have been recognized by clinicians for over 100 years. Recent studies, however, have begun to distinguish whether these mood disorders represent primary disorders or are a secondary consequence of the cerebral infarction. Although poststroke mood disorders share similarities with primary mood disorders in their clinical phenomenology, longitudinal course, and response to treatment, clinical-pathologic correlations during the acute poststroke period have provided a strong argument that these disorders are frequently etiologically linked to the cerebral ischemia. Major depression during the acute stroke period was associated with left frontal and left basal ganglia lesions, while mania was associated with right orbital frontal, basotemporal, basal ganglia, or thalamic lesions. Identification of the mechanism of these disorders will ultimately establish their "secondariness" as well as development of more focused treament strategies.
 ...
PMID:Mood Disorders Secondary to Stroke. 1032 Apr 68

The identification of comorbid disorders in migraineurs is important since it may impose therapeutic challenges and limit treatment options. Moreover, the study of comorbidity might lead to improve our knowledge about causes and consequences of migraine. Comorbid neuropathologies in migraine may involve mood disorders (depression, mania, anxiety, panic attacks), epilepsy, essential tremor, stroke, and white matter abnormalities. Particularly, a complex bidirectional relation exists between migraine and stroke, including migraine as a risk factor for cerebral ischemia, migraine caused by cerebral ischemia, migraine as a cause of stroke, migraine mimicking cerebral ischemia, migraine and cerebral ischemia sharing a common cause, and migraine associated with subclinical vascular brain lesions.
 ...
PMID:Comorbid neuropathologies in migraine. 1676 30