Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0917798 (cerebral ischemia)
 17,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 28 year old woman with a previous history of labile hypertension, migraine and transitory cerebral ischemia was admitted with cerebral infarction. One month later she developed livedo reticularis and amaurosis fugax, which led to the diagnosis of Sneddon's disease (livedo reticularis, labile hypertension and neurological symptoms) and the anticardiolipin antibody (ACA) syndrome. Treatment with prednisone and phenprocoumon resulted in lowering of ACA-titers, but the symptoms did not subside until acetylsalicylic acid was added.
 ...
PMID:[Anti-cardiolipin antibody in cerebral infarction]. 198 66

The patient was 47 years old on his first visit in 1969 and has been treated at our outpatient clinic until now, at the age of 79. The initial blood pressure was 164/98 mmHg without abnormalities on electrocardiogram or urinalysis. He was followed-up for 8 years with non-pharmacologic treatment, which was eventually changed to antihypertensive drug treatment. At the age of 71 he was admitted because blood pressure increased to 210/110 mmHg, with marked fluctuation. At admission bilateral ocular (right < left) and carotid bruits (right < left) were detected. At the age of 75 he had cerebellar infarction with reversible neuro-logic deficits. At the age of 76 he was again addmitted because the labile hypertension was difficult to control. Cerebral angiography which was performed to clarify the relationship between labile hypertension and cerebral ischemia revealed significant bilateral stenosis at the portion of the cavernous sinus in the internal carotid arteries. The stenosis was more remarkable on the left side than the right side. Based on the angiographic findings we considered the ocular bruits to be not a murmur of augmentation flow but a stenotic murmur.
 ...
PMID:[An elderly hypertensive patient with ocular bruits and angiographically confirmed stenosis of intracranical internal carotid arteries]. 1185 82