Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0854467 (myelosuppression)
 5,932 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
HDJ2 protein 11.4
NUDT15 9.6
HLF protein 9.6
solute carrier family 19 member 1 9.4
thiopurine methyltransferase 9.4
CD37 antigen 9.2
BAZF 8.9
IFN-alpha 5 8.9
thiopurine S-methyltransferase 8.7
CDHP 8.6
CAPZA2 8.6
hmlh1 8.6
NOVP 8.5
Interleukin 11 8.4
MNSOD 8.3
ABIN-3 8.1
glycinamide ribonucleotide formyltransferase 8.1
CCNU 8.1
Pom 8.1
ERIC-1 8.0
CANX 8.0
SCGF 7.9
CLL1 7.9
CALCR 7.9
ITPase 7.9
bone marrow stromal cell-derived 7.8
DDCT 7.8
ACYP2 7.7
cytochrome P450 CYP3A4 7.6
signal transducer and activator of transcription 5A 7.6
ICRF 7.6
HOXB5 7.6
HDJ-2 7.6
Granulocyte colony stimulating factor 7.5
EAP 7.5
SLC7A6 7.5
HSDJ 7.5
SZP 7.5
CTL4 7.4
ovastacin 7.4
SEMA5A 7.4
granulocyte colony-stimulating factor 7.3
HD9 7.3
HOXB2 7.2
MVP 7.2
NAB1 7.2
MLL5 7.2
MUL 7.2
RAPA 7.1
MTD 7.1
megakaryocyte growth and development factor 7.1
hepatic leukemia factor 7.1
ara 7.1
MNX 7.0
CAV 7.0
granulocyte-macrophage 6.9
PYM 6.9
Cav1.4 6.9
CXCL12 protein 6.9
TECK 6.9
Siglec-3 6.8
G-CSF 6.8
cytochrome P450 3A5 6.7
glomulin 6.7
JMJD1C 6.7
KCNMB1 6.7
TIE1 6.6
Granulocyte-colony stimulating factor 6.6
SNM1B 6.6
HSP90B1 6.6
non-Hodgkin's lymphoma 6.5
Interleukin-3 6.5
CD20 antigen 6.5
PFL 6.5
FLT3L 6.5
L-asparaginase 6.5
GPI anchor biosynthesis 6.4
LPA4 6.4
PRMT7 6.4
Interleukin-11 6.3
more...
Disease
myelosuppression 12.4
Thiopurine methyltransferase deficiency 11.7
relapsed adult ALL 11.4
Retrocecal appendicitis 10.8
Pneumonia due to Pseudomonas 10.8
Superficial phlebitis 10.8
stage IVB cervical cancer 10.8
Marrow dysplasia 10.4
Vulvitis circumscripta plasmacellularis 10.4
nonmetastatic GTT 10.1
Chemical cystitis 9.8
Tumor flare 9.8
AIDS-related primary CNS lymphoma 9.8
stage II ovarian cancer 9.2
AIDS-related Hodgkin's disease 9.2
Systemic aspergillosis 9.2
Drug-induced neutropenia 9.2
Placental infarction 9.2
CACP 9.1
adult solid tumor 9.1
Hodgkin's disease refractory 9.1
stage IV non-Hodgkin's lymphoma 9.1
recurrent uterine sarcoma 9.1
measurable disease 9.1
recurrent neuroblastoma 9.0
Relative polycythaemia 8.9
acute stomatitis 8.9
recurrent SCLC 8.9
acute stomatitis 8.9
refractory hairy cell leukemia 8.8
Disseminated aspergillosis 8.7
adult soft tissue sarcoma 8.7
FAB L2 8.6
Granulocytosis 8.6
relapsed CML 8.5
Neutropenic sepsis 8.5
recurrent retinoblastoma 8.5
hand-foot syndrome 8.4
Non-occlusive mesenteric ischemia 8.4
recurrent cervical cancer 8.4
evaluable disease 8.3
stage III multiple myeloma 8.2
Chemotherapy-induced neutropenia 8.2
extensive stage SCLC 8.2
leukopenia 8.1
Insular carcinoma 8.1
Febrile neutropenia 8.0
refractory testicular cancer 8.0
cheilosis 7.9
metastatic esophageal cancer 7.9
Hemorrhagic enteritis 7.9
adenocarcinoma of unknown primary 7.9
brain stem glioma 7.9
recurrent colon cancer 7.9
GVM 7.9
Hepatic infarction 7.9
recurrent ovarian cancer 7.9
metastatic Ewing's sarcoma 7.8
upper GI cancer 7.8
neutropenia 7.8
RAEB-1 7.8
metastatic endometrial cancer 7.7
metastatic hypernephroma 7.7
refractory CLL 7.7
DPD deficiency 7.7
limited-stage small cell lung cancer 7.7
RAEB-2 7.7
Clostridium septicum infection 7.6
Ototoxicity 7.6
Bone marrow toxicity 7.5
Azotemia 7.5
pleuropericarditis 7.5
Clonal evolution 7.5
stage IV NSCLC 7.5
recurrent endometrial cancer 7.5
Hemorrhagic cystitis 7.4
RAEB-T 7.4
Reactive thrombocytosis 7.3
Bone marrow depression 7.3
agranulocytosis 7.3
more...
Symptom
Chills and fever 10.1
Generalized fatigue 9.8
nausea and vomiting 8.1
Reticulocytosis 7.8
Flu-like symptoms 7.6
diminished hearing 7.3
nausea 6.7
testicular pain 6.5
asthenia 6.4
GI irritation 6.4
vomiting 6.3
Skin symptoms 6.3
lassitude 6.2
onychomadesis 5.9
rigors 5.9
anorexia 5.7
Cushingoid 5.6
Cushingoid 5.6
bone pain 5.5
periorbital edema 5.4
muscle cramps 5.4
diarrhea 5.3
dark urine 5.3
chills 5.2
generalized rash 5.2
myalgia 5.1
meningism 5.0
Flare 4.9
Gastrointestinal symptoms 4.8
fever of unknown origin 4.7
inanition 4.6
Ill 4.5
tenesmus 4.5
anal pain 4.5
paresthesia 4.4
lethargy 4.4
hyperesthesia 4.3
splenomegaly 4.3
fatigue 4.3
non-productive cough 4.3
decreased appetite 4.2
pleuritic chest pain 4.2
hot flushes 4.1
loin pain 4.0
leg edema 4.0
constipation 4.0
eye pain 3.8
photophobia 3.8
intestinal bleeding 3.7
dysuria 3.7
tingling 3.7
flushing 3.7
abdominal discomfort 3.6
stomach pain 3.4
arm pain 3.4
dry skin 3.4
arthralgia 3.4
lightheadedness 3.4
erythema 3.4
sleepiness 3.3
Decreased activity 3.3
swollen joints 3.3
retching 3.3
neck stiffness 3.1
dizziness 3.1
asynergy 3.0
tonic-clonic seizure 3.0
thigh pain 3.0
epigastric pain 3.0
chest tightness 2.8
tinnitus 2.7
hepatosplenomegaly 2.6
dyspnea 2.5
sneezing 2.5
HSA 2.4
otalgia 2.4
blurred vision 2.4
shortness of breath 2.4
emaciation 2.3
headache 2.3
more...
Drug
5-Oxo-L-Norleucine 12.4
Emitefur 11.4
Trimetrexate glucuronate 11.4
Romurtide 10.8
Eniluracil 10.8
Eniluracil 10.8
Etoposide phosphate 10.7
Edatrexate 10.6
Ifex 10.4
Leridistim 10.4
Ganciclovir sodium 10.4
Topotecan hydrochloride 10.1
Stilphostrol 10.1
Stilphostrol 10.1
Mesnex 10.1
Nartograstim 10.1
Teroxirone 10.1
Ormaplatin 9.7
Indisulam 9.6
Adozelesin 9.6
Menogaril 9.4
Rubitecan 9.4
Ibritumomab tiuxetan 9.3
Satraplatin 9.2
Carbetimer 9.1
Isovorin 8.9
Novantrone 8.9
Alimta 8.9
Temodal 8.9
Vindesine 8.9
Paraplatin 8.8
Teniposide 8.8
Vindesine 8.8
Lonafarnib 8.8
Quadramet 8.7
Doxifluridine 8.7
Fludarabine 8.6
Leukine 8.5
Idarubicin 8.5
Maribavir 8.5
Irofulven 8.4
Gallium nitrate 8.4
Nelarabine 8.4
Fotemustine 8.4
Thioguanine 8.3
Ixabepilone 8.3
anti-CD33 8.3
Proleukin 8.3
Bexxar 8.3
Etoposide 8.2
Zevalin 8.2
Ethyol 8.2
Epidoxorubicin 8.2
Pirarubicin 8.2
Clofarabine 8.1
Mercaptopurine 8.0
Nipent 8.0
Vinorelbine 8.0
Gliadel 8.0
Dacogen 7.9
Navelbine 7.9
Sizofiran 7.9
Tipifarnib 7.8
Gemzar 7.8
Filgrastim 7.8
Pemetrexed 7.7
Xeloda 7.7
Amifostine 7.7
Filgrastim 7.6
Zyvox 7.6
Lisofylline 7.6
Aclarubicin 7.6
Leucovorin 7.6
Lenalidomide 7.6
ARA-C 7.5
Ontak 7.5
Ontak 7.5
Sodium thiosulfate 7.4
Irinotecan 7.4
Pixantrone 7.3
more...
Enzyme
DHAD 9.2
thiopurine methyltransferase 9.0
EC 3.6.1.19 8.9
MTD 7.0
TUT 6.7
GMP synthase 6.6
dihydropyrimidine dehydrogenase 6.4
dihydropyrimidine dehydrogenase 6.2
asparaginase 6.1
deoxycytidine deaminase 6.0
carboxypeptidase G2 5.9
cytidine deaminase 5.8
deoxycytidine kinase 5.7
farnesyltransferase 5.5
CTP synthase 5.5
thymidine phosphorylase 5.4
thymidylate synthase 5.3
deoxyguanosine kinase 5.2
glycinamide ribonucleotide transformylase 5.2
CEP 5.2
inosine triphosphatase 5.1
dihydrofolate reductase 5.0
farnesyltransferase 5.0
dihydroorotate dehydrogenase 5.0
dihydroorotate dehydrogenase 5.0
adenylosuccinate synthetase 4.7
aspartate transcarbamylase 4.6
aminopeptidase B 4.6
CEP 4.6
lactic acid dehydrogenase 4.6
ribonucleotide reductase 4.5
methylthioadenosine phosphorylase 4.5
ribonucleotide reductase 4.5
lactic acid dehydrogenase 4.5
BMT 4.5
adenosine deaminase 4.4
adenosine deaminase 4.4
orotate phosphoribosyltransferase 4.0
Fpg protein 4.0
topoisomerase 4.0
type III procollagen 4.0
folylpolyglutamate synthetase 3.9
topoisomerase 3.9
DNA methyltransferase 3.9
nucleotide pyrophosphatase 3.9
SNO 3.8
lactic acid dehydrogenase 3.8
AGT 3.8
legumain 3.8
TACE 3.8
galactocerebrosidase 3.7
P-glycoprotein 3.7
MDR 3.6
CGT 3.6
ALDH 3.6
IMP dehydrogenase 3.6
PAM 3.5
glucosylceramide synthase 3.5
prostate-specific antigen 3.3
dihydropteroate synthase 3.3
caspase-1 3.2
prostate-specific membrane antigen 3.2
thyroid peroxidase 3.1
MDP 3.0
AST 3.0
glutathione synthetase 3.0
methylenetetrahydrofolate reductase 2.9
purine nucleoside phosphorylase 2.9
methylenetetrahydrofolate reductase 2.9
alanine aminopeptidase 2.9
DAT 2.9
cytosine deaminase 2.8
SST 2.8
focal adhesion kinase 2.8
CPT 2.8
methionine synthase 2.7
alanine aminotransferase 2.6
CPT 2.6
methionine synthase 2.6
DCF 2.5
more...
Compound
Spiroplatin 12.4
Estramustine phosphate sodium 11.4
Asaley 11.4
Mesuol 11.4
Fazarabine 11.0
Baker's Antifol 10.8
Fazarabine 10.8
Fludarabine phosphate 10.6
Pyrazine diazohydroxide 10.6
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
DHAC 10.4
PalmO-ara-C 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
AZQ 10.2
Trimetrexate 10.1
Stilphostrol 10.1
Pyrazine diazohydroxide 9.9
PCNU 9.9
Indicine 9.8
C9H8O2 9.8
Foscarnet sodium 9.8
C9H8O2 9.8
Deoxydoxorubicin 9.8
C9H8O2 9.8
Homoharringtonine 9.7
C9H8O2 9.6
AAFC 9.6
GANU 9.6
C9H8O2 9.6
7-OMEN 9.6
Topotecan 9.4
C5H12N2 9.4
GANU 9.3
atropic acid 9.2
C9H8O2 9.1
Clomesone 9.1
Ara-G 9.1
Ara-G 9.1
TMQ 9.1
Ifosfamide 9.0
Prednimustine 8.9
Topotecan 8.9
BPQ 8.8
CBDCA 8.8
CBDCA 8.8
cephalotaxine 8.7
CI-941 8.7
Mitozolomide 8.7
MCNU 8.7
Dihydrocoumarin 8.6
HECNU 8.6
Tiazofurin 8.5
Mitoxantrone 8.5
PALA 8.5
Echinomycin 8.5
MeCCNU 8.5
Epirubicin 8.5
2,6-piperazinedione 8.5
Mesna 8.5
THP-ADM 8.4
Cyclocytidine 8.4
Porfiromycin 8.4
cephalotaxine 8.4
Mitoxantrone 8.3
Chlorozotocin 8.3
L-Alanosine 8.2
Amonafide 8.2
trans-Cinnamic acid 8.2
Tetraplatin 8.2
Deoxycoformycin 8.2
6-Thioguanine 8.2
Inox 8.1
Pyrazofurin 8.1
more...