Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0854467 (myelosuppression)
5,932 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 333
granulocyte colony-stimulating factor 220
non-Hodgkin's lymphoma 197
granulocyte 194
CSF 110
cytokine 107
G-CSF 105
interferon 100
erythroid 89
hemoglobin 89
granulocyte-macrophage 85
lymphoid 84
granulocyte-macrophage colony-stimulating factor 75
GM-CSF 74
Mol 57
AML 53
erythropoietin 53
ara 53
IFN 49
topoisomerase I 46
CCNU 45
CD34 45
megakaryocyte 43
CHOP 43
thiopurine methyltransferase 41
tyrosine kinase 39
CD4 38
osteosarcoma 37
macrophage colony-stimulating factor 36
CD20 35
thrombopoietin 35
She 34
IL-3 34
ALL 34
dihydrofolate reductase 34
thymus 33
IL-6 33
P-glycoprotein 32
stem cell factor 31
thiopurine S-methyltransferase 28
interferon-alpha 27
alkaline phosphatase 27
HLA 27
nodal 27
DDP 27
CTX 26
NHL 26
JAK2 26
L-asparaginase 25
albumin 25
tumor necrosis factor 25
IL-1 25
rhabdomyosarcoma 25
LDH 25
thymidylate synthase 24
CD33 24
p53 23
interleukin-6 22
CML 22
c-kit 21
interferon alpha 20
adenosine deaminase 20
TNF 20
MDR1 19
methylguanine-DNA methyltransferase 19
glycoprotein 19
lactate dehydrogenase 19
Interleukin-3 18
CD8 18
dihydropyrimidine dehydrogenase 17
hematopoietic stem and progenitor cells 17
mTOR 17
BCR 16
serum albumin 16
VIP 16
vascular endothelial growth factor 15
MTX 15
FLT3 15
all-trans 15
CLL 14
more...
Disease
myelosuppression 5932
cancer 2283
tumor 862
thrombocytopenia 753
neutropenia 724
breast cancer 386
leukopenia 385
leukemia 361
lymphoma 358
acute myeloid leukemia 327
carcinoma 311
anemia 276
lung cancer 254
non-small cell lung cancer 228
non-Hodgkin's lymphoma 228
stomatitis 222
Hodgkin's disease 211
metastases 202
sepsis 192
ovarian cancer 191
acute lymphoblastic leukemia 174
metastatic breast cancer 169
sepsis 163
multiple myeloma 154
acute leukemia 146
melanoma 143
chronic myeloid leukemia 140
adenocarcinoma 140
myelodysplastic syndrome 135
small cell lung cancer 133
squamous cell carcinoma 128
peripheral neuropathy 127
colorectal cancer 119
agranulocytosis 118
chronic lymphocytic leukemia 114
rash 114
pneumonia 109
epithelial ovarian cancer 109
lung carcinoma 104
chronic lymphocytic leukemia 94
sarcoma 91
neuropathy 91
measurable disease 83
head and neck cancer 82
prostate cancer 79
pancytopenia 71
gastric cancer 70
glioma 68
hematologic malignancies 67
residual disease 67
cytomegalovirus 65
Leukemia 64
renal cell carcinoma 58
osteosarcoma 57
tumor growth 56
congestive heart failure 56
graft-versus-host disease 56
AIDS 53
renal failure 51
neuroblastoma 50
tumor progression 50
HIV 49
phlebitis 49
bladder cancer 48
cervical cancer 44
renal impairment 43
hepatocellular carcinoma 42
hand-foot syndrome 42
myelofibrosis 42
liver metastases 41
acute nonlymphocytic leukemia 40
colon cancer 40
influenza 40
pancreatic cancer 39
bone metastases 39
solid tumor 38
cystitis 36
glioblastoma 36
hypertension 36
immunodeficiency 36
more...
Symptom
nausea and vomiting 481
vomiting 481
nausea 460
diarrhea 409
fatigue 193
anorexia 137
pain 98
headache 52
Ill 48
asthenia 43
myalgia 41
splenomegaly 37
dyspnea 30
chills 30
constipation 30
seizures 30
bone pain 26
weakness 26
erythema 25
abdominal pain 25
sleepiness 24
lethargy 22
paresthesia 20
flushing 15
dizziness 15
arthralgia 14
chest pain 12
ataxia 12
fever of unknown origin 10
respiratory distress 10
anesthesia 9
rigors 9
discomfort 8
tinnitus 8
discomfort 8
cough 7
muscle cramps 7
exhaustion 6
testicular pain 6
tremor 6
dysuria 6
hepatomegaly 5
agitation 5
hepatosplenomegaly 5
epigastric pain 5
shortness of breath 5
decreased appetite 4
abdominal discomfort 4
photophobia 4
lassitude 4
analgesia 4
hot flushes 4
numbness 4
HSA 3
memory loss 3
back pain 3
Gastrointestinal symptoms 3
tingling 3
cachexia 3
dry skin 2
exertional dyspnea 2
dark urine 2
pleuritic chest pain 2
tenesmus 2
hyperesthesia 2
hemoptysis 2
leg edema 2
Cushingoid 2
collapse 2
Flu-like symptoms 2
periorbital edema 2
tonic-clonic seizure 2
blurred vision 2
Cushingoid 2
acute pain 2
meningism 2
dysarthria 2
Reticulocytosis 2
intestinal bleeding 2
sneezing 2
more...
Drug
CSF 174
Adriamycin 121
G-CSF 118
CTX 68
Taxol 66
Etoposide 64
TTC 52
Docetaxel 42
CPT-11 35
Fludarabine 33
CTX 26
CTX 26
Irinotecan 25
Lenalidomide 23
Vinorelbine 20
anti-CD33 20
Dermatol 19
Leucovorin 18
Novantrone 18
-deoxyadenosine 17
VCR 17
ADM 17
Pemetrexed 16
IL-2 15
Filgrastim 15
Rituximab 15
Taxotere 15
Filgrastim 15
Imatinib 15
Amifostine 14
Idarubicin 14
Gleevec 12
Cremophor EL 11
MDS 11
Oxaliplatin 10
Vindesine 10
Vindesine 10
GEO 9
Dasatinib 9
BLM 9
Teniposide 8
Navelbine 8
ARA-C 8
Gemzar 8
IFN-gamma 8
ADR 7
Zevalin 7
Campath 7
Clofarabine 7
caffeine 7
Campath 7
Cardiovasc 7
PFA 7
Alimta 7
VCR 6
Ethyol 6
Xeloda 6
Monit 6
CTC 6
Etoposide phosphate 6
Edatrexate 6
Herceptin 6
HCG 6
CTC 6
Ixabepilone 5
Ganciclovir 5
Pirarubicin 5
Lipiodol 5
AZT 5
Mitomycin-C 5
Prednisolone 5
AraC 5
Gallium nitrate 5
Dexrazoxane 5
IFN-beta 4
Asparaginase 4
vitamin E 4
Bexxar 4
Prednisone 4
AZT 4
more...
Enzyme
ERK 57
focal adhesion kinase 56
thiopurine methyltransferase 51
dihydrofolate reductase 35
asparaginase 34
P-glycoprotein 32
alanine aminotransferase 31
topoisomerase 29
thymidylate synthase 27
alkaline phosphatase 27
lactate dehydrogenase 26
topoisomerase 26
adenosine deaminase 20
adenosine deaminase 20
aspartate aminotransferase 19
dihydropyrimidine dehydrogenase 17
superoxide dismutase 15
catalase 15
DNA methyltransferase 14
calcineurin 14
MTD 14
ribonucleotide reductase 13
PARP 13
prostate-specific antigen 13
dihydropyrimidine dehydrogenase 13
ribonucleotide reductase 12
caspase-1 11
BMT 11
peroxidase 11
MDR 10
cytidine deaminase 10
farnesyltransferase 9
mitogen-activated protein kinase 9
farnesyltransferase 9
proteasome 9
AST 9
glutathione peroxidase 8
thymidine phosphorylase 8
monoamine oxidase 7
deoxycytidine kinase 7
caspase-3 7
creatine kinase 7
DHAD 7
glutathione S-transferase 6
CEP 5
DNA polymerase 5
NQO1 5
protein kinase 5
thyroid peroxidase 5
aldehyde dehydrogenase 5
CEP 5
MDP 4
CPT 4
CPT 4
aspartate transcarbamylase 4
reverse transcriptase 4
lipase 4
PAM 4
ACE 4
CPT 4
MEK 4
ACS 4
xanthine oxidase 4
ornithine decarboxylase 3
prostate-specific membrane antigen 3
CYP3A4 3
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
phosphoinositide 3-kinase 3
plasmin 3
aldehyde dehydrogenase 3
methylenetetrahydrofolate reductase 3
aldehyde dehydrogenase 3
dihydroorotate dehydrogenase 3
dihydroorotate dehydrogenase 3
acid phosphatase 3
carboxylesterase 3
methylenetetrahydrofolate reductase 3
protein kinase C 3
purine nucleoside phosphorylase 2
more...
Compound
Clin 778
Dec 391
DNA 297
Adriamycin 158
VP-16 157
5-FU 143
creatinine 130
DDP 117
CBDCA 115
CBDCA 115
Ara-C 81
water 73
BCNU 73
CTX 68
Paclitaxel 66
Ara-C 63
Gemcitabine 62
Gemcitabine 62
Methotrexate 59
ADR 55
Ifosfamide 51
Topotecan 51
Topotecan 51
phosphate 50
folinic acid 45
CCNU 45
pyrimidine 43
pyrimidine 43
Mitoxantrone 43
oxygen 40
Mitoxantrone 39
DIC 35
Docetaxel 35
CPT-11 34
iron 33
nitrogen 33
MMC 32
AZQ 29
sodium 28
Epirubicin 27
Azathioprine 26
Linezolid 26
calcium 25
ACNU 25
PEG 25
Hydroxyurea 24
Temozolomide 24
BLM 21
urea 20
MeCCNU 20
TNF 20
retinoic acid 19
acetate 19
sulfate 18
PALA 18
bis(2-chloroethyl) 18
VM-26 18
bis(2-chloroethyl) 18
L-PAM 18
L-PAM 18
Capecitabine 18
bis(2-chloroethyl) 18
tyrosine 17
CAM 17
glucose 17
TMQ 17
iodine 17
galactose 17
Trimetrexate 17
Vincristine 17
Optimal 16
Mesna 16
BCR 16
CHIP 16
MTX 15
CAP 15
Homoharringtonine 14
Amifostine 14
ABL 14
salt 14
more...