Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0854467 (
myelosuppression
)
5,932
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
333
granulocyte colony-stimulating factor
220
non-Hodgkin's lymphoma
197
granulocyte
194
CSF
110
cytokine
107
G-CSF
105
interferon
100
erythroid
89
hemoglobin
89
granulocyte-macrophage
85
lymphoid
84
granulocyte-macrophage colony-stimulating factor
75
GM-CSF
74
Mol
57
AML
53
erythropoietin
53
ara
53
IFN
49
topoisomerase I
46
CCNU
45
CD34
45
megakaryocyte
43
CHOP
43
thiopurine methyltransferase
41
tyrosine kinase
39
CD4
38
osteosarcoma
37
macrophage colony-stimulating factor
36
CD20
35
thrombopoietin
35
She
34
IL-3
34
ALL
34
dihydrofolate reductase
34
thymus
33
IL-6
33
P-glycoprotein
32
stem cell factor
31
thiopurine S-methyltransferase
28
interferon-alpha
27
alkaline phosphatase
27
HLA
27
nodal
27
DDP
27
CTX
26
NHL
26
JAK2
26
L-asparaginase
25
albumin
25
tumor necrosis factor
25
IL-1
25
rhabdomyosarcoma
25
LDH
25
thymidylate synthase
24
CD33
24
p53
23
interleukin-6
22
CML
22
c-kit
21
interferon alpha
20
adenosine deaminase
20
TNF
20
MDR1
19
methylguanine-DNA methyltransferase
19
glycoprotein
19
lactate dehydrogenase
19
Interleukin-3
18
CD8
18
dihydropyrimidine dehydrogenase
17
hematopoietic stem and progenitor cells
17
mTOR
17
BCR
16
serum albumin
16
VIP
16
vascular endothelial growth factor
15
MTX
15
FLT3
15
all-trans
15
CLL
14
more...
Disease
myelosuppression
5932
cancer
2283
tumor
862
thrombocytopenia
753
neutropenia
724
breast cancer
386
leukopenia
385
leukemia
361
lymphoma
358
acute myeloid leukemia
327
carcinoma
311
anemia
276
lung cancer
254
non-small cell lung cancer
228
non-Hodgkin's lymphoma
228
stomatitis
222
Hodgkin's disease
211
metastases
202
sepsis
192
ovarian cancer
191
acute lymphoblastic leukemia
174
metastatic breast cancer
169
sepsis
163
multiple myeloma
154
acute leukemia
146
melanoma
143
chronic myeloid leukemia
140
adenocarcinoma
140
myelodysplastic syndrome
135
small cell lung cancer
133
squamous cell carcinoma
128
peripheral neuropathy
127
colorectal cancer
119
agranulocytosis
118
chronic lymphocytic leukemia
114
rash
114
pneumonia
109
epithelial ovarian cancer
109
lung carcinoma
104
chronic lymphocytic leukemia
94
sarcoma
91
neuropathy
91
measurable disease
83
head and neck cancer
82
prostate cancer
79
pancytopenia
71
gastric cancer
70
glioma
68
hematologic malignancies
67
residual disease
67
cytomegalovirus
65
Leukemia
64
renal cell carcinoma
58
osteosarcoma
57
tumor growth
56
congestive heart failure
56
graft-versus-host disease
56
AIDS
53
renal failure
51
neuroblastoma
50
tumor progression
50
HIV
49
phlebitis
49
bladder cancer
48
cervical cancer
44
renal impairment
43
hepatocellular carcinoma
42
hand-foot syndrome
42
myelofibrosis
42
liver metastases
41
acute nonlymphocytic leukemia
40
colon cancer
40
influenza
40
pancreatic cancer
39
bone metastases
39
solid tumor
38
cystitis
36
glioblastoma
36
hypertension
36
immunodeficiency
36
more...
Symptom
nausea and vomiting
481
vomiting
481
nausea
460
diarrhea
409
fatigue
193
anorexia
137
pain
98
headache
52
Ill
48
asthenia
43
myalgia
41
splenomegaly
37
dyspnea
30
chills
30
constipation
30
seizures
30
bone pain
26
weakness
26
erythema
25
abdominal pain
25
sleepiness
24
lethargy
22
paresthesia
20
flushing
15
dizziness
15
arthralgia
14
chest pain
12
ataxia
12
fever of unknown origin
10
respiratory distress
10
anesthesia
9
rigors
9
discomfort
8
tinnitus
8
discomfort
8
cough
7
muscle cramps
7
exhaustion
6
testicular pain
6
tremor
6
dysuria
6
hepatomegaly
5
agitation
5
hepatosplenomegaly
5
epigastric pain
5
shortness of breath
5
decreased appetite
4
abdominal discomfort
4
photophobia
4
lassitude
4
analgesia
4
hot flushes
4
numbness
4
HSA
3
memory loss
3
back pain
3
Gastrointestinal symptoms
3
tingling
3
cachexia
3
dry skin
2
exertional dyspnea
2
dark urine
2
pleuritic chest pain
2
tenesmus
2
hyperesthesia
2
hemoptysis
2
leg edema
2
Cushingoid
2
collapse
2
Flu-like symptoms
2
periorbital edema
2
tonic-clonic seizure
2
blurred vision
2
Cushingoid
2
acute pain
2
meningism
2
dysarthria
2
Reticulocytosis
2
intestinal bleeding
2
sneezing
2
more...
Drug
CSF
174
Adriamycin
121
G-CSF
118
CTX
68
Taxol
66
Etoposide
64
TTC
52
Docetaxel
42
CPT-11
35
Fludarabine
33
CTX
26
CTX
26
Irinotecan
25
Lenalidomide
23
Vinorelbine
20
anti-CD33
20
Dermatol
19
Leucovorin
18
Novantrone
18
-deoxyadenosine
17
VCR
17
ADM
17
Pemetrexed
16
IL-2
15
Filgrastim
15
Rituximab
15
Taxotere
15
Filgrastim
15
Imatinib
15
Amifostine
14
Idarubicin
14
Gleevec
12
Cremophor EL
11
MDS
11
Oxaliplatin
10
Vindesine
10
Vindesine
10
GEO
9
Dasatinib
9
BLM
9
Teniposide
8
Navelbine
8
ARA-C
8
Gemzar
8
IFN-gamma
8
ADR
7
Zevalin
7
Campath
7
Clofarabine
7
caffeine
7
Campath
7
Cardiovasc
7
PFA
7
Alimta
7
VCR
6
Ethyol
6
Xeloda
6
Monit
6
CTC
6
Etoposide phosphate
6
Edatrexate
6
Herceptin
6
HCG
6
CTC
6
Ixabepilone
5
Ganciclovir
5
Pirarubicin
5
Lipiodol
5
AZT
5
Mitomycin-C
5
Prednisolone
5
AraC
5
Gallium nitrate
5
Dexrazoxane
5
IFN-beta
4
Asparaginase
4
vitamin E
4
Bexxar
4
Prednisone
4
AZT
4
more...
Enzyme
ERK
57
focal adhesion kinase
56
thiopurine methyltransferase
51
dihydrofolate reductase
35
asparaginase
34
P-glycoprotein
32
alanine aminotransferase
31
topoisomerase
29
thymidylate synthase
27
alkaline phosphatase
27
lactate dehydrogenase
26
topoisomerase
26
adenosine deaminase
20
adenosine deaminase
20
aspartate aminotransferase
19
dihydropyrimidine dehydrogenase
17
superoxide dismutase
15
catalase
15
DNA methyltransferase
14
calcineurin
14
MTD
14
ribonucleotide reductase
13
PARP
13
prostate-specific antigen
13
dihydropyrimidine dehydrogenase
13
ribonucleotide reductase
12
caspase-1
11
BMT
11
peroxidase
11
MDR
10
cytidine deaminase
10
farnesyltransferase
9
mitogen-activated protein kinase
9
farnesyltransferase
9
proteasome
9
AST
9
glutathione peroxidase
8
thymidine phosphorylase
8
monoamine oxidase
7
deoxycytidine kinase
7
caspase-3
7
creatine kinase
7
DHAD
7
glutathione S-transferase
6
CEP
5
DNA polymerase
5
NQO1
5
protein kinase
5
thyroid peroxidase
5
aldehyde dehydrogenase
5
CEP
5
MDP
4
CPT
4
CPT
4
aspartate transcarbamylase
4
reverse transcriptase
4
lipase
4
PAM
4
ACE
4
CPT
4
MEK
4
ACS
4
xanthine oxidase
4
ornithine decarboxylase
3
prostate-specific membrane antigen
3
CYP3A4
3
aldehyde dehydrogenase
3
aldehyde dehydrogenase
3
phosphoinositide 3-kinase
3
plasmin
3
aldehyde dehydrogenase
3
methylenetetrahydrofolate reductase
3
aldehyde dehydrogenase
3
dihydroorotate dehydrogenase
3
dihydroorotate dehydrogenase
3
acid phosphatase
3
carboxylesterase
3
methylenetetrahydrofolate reductase
3
protein kinase C
3
purine nucleoside phosphorylase
2
more...
Compound
Clin
778
Dec
391
DNA
297
Adriamycin
158
VP-16
157
5-FU
143
creatinine
130
DDP
117
CBDCA
115
CBDCA
115
Ara-C
81
water
73
BCNU
73
CTX
68
Paclitaxel
66
Ara-C
63
Gemcitabine
62
Gemcitabine
62
Methotrexate
59
ADR
55
Ifosfamide
51
Topotecan
51
Topotecan
51
phosphate
50
folinic acid
45
CCNU
45
pyrimidine
43
pyrimidine
43
Mitoxantrone
43
oxygen
40
Mitoxantrone
39
DIC
35
Docetaxel
35
CPT-11
34
iron
33
nitrogen
33
MMC
32
AZQ
29
sodium
28
Epirubicin
27
Azathioprine
26
Linezolid
26
calcium
25
ACNU
25
PEG
25
Hydroxyurea
24
Temozolomide
24
BLM
21
urea
20
MeCCNU
20
TNF
20
retinoic acid
19
acetate
19
sulfate
18
PALA
18
bis(2-chloroethyl)
18
VM-26
18
bis(2-chloroethyl)
18
L-PAM
18
L-PAM
18
Capecitabine
18
bis(2-chloroethyl)
18
tyrosine
17
CAM
17
glucose
17
TMQ
17
iodine
17
galactose
17
Trimetrexate
17
Vincristine
17
Optimal
16
Mesna
16
BCR
16
CHIP
16
MTX
15
CAP
15
Homoharringtonine
14
Amifostine
14
ABL
14
salt
14
more...