Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0854467 (myelosuppression)
 5,932 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HDJ2 protein 11.4
NUDT15 9.6
HLF protein 9.6
solute carrier family 19 member 1 9.4
thiopurine methyltransferase 9.4
CD37 antigen 9.2
IFN-alpha 5 8.9
BAZF 8.9
thiopurine S-methyltransferase 8.7
CDHP 8.6
CAPZA2 8.6
hmlh1 8.6
NOVP 8.5
Interleukin 11 8.4
MNSOD 8.3
ABIN-3 8.1
glycinamide ribonucleotide formyltransferase 8.1
CCNU 8.1
Pom 8.1
CANX 8.0
ERIC-1 8.0
SCGF 7.9
CALCR 7.9
CLL1 7.9
ITPase 7.9
bone marrow stromal cell-derived 7.8
DDCT 7.8
ACYP2 7.7
signal transducer and activator of transcription 5A 7.6
cytochrome P450 CYP3A4 7.6
ICRF 7.6
HDJ-2 7.6
HOXB5 7.6
Granulocyte colony stimulating factor 7.5
EAP 7.5
SLC7A6 7.5
SZP 7.5
HSDJ 7.5
ovastacin 7.4
SEMA5A 7.4
more...
Disease
myelosuppression 12.4
Thiopurine methyltransferase deficiency 11.7
relapsed adult ALL 11.4
Pneumonia due to Pseudomonas 10.8
Superficial phlebitis 10.8
stage IVB cervical cancer 10.8
Retrocecal appendicitis 10.8
Marrow dysplasia 10.4
Vulvitis circumscripta plasmacellularis 10.4
nonmetastatic GTT 10.1
Chemical cystitis 9.8
AIDS-related primary CNS lymphoma 9.8
Tumor flare 9.8
stage II ovarian cancer 9.2
AIDS-related Hodgkin's disease 9.2
Drug-induced neutropenia 9.2
Placental infarction 9.2
Systemic aspergillosis 9.2
recurrent uterine sarcoma 9.1
adult solid tumor 9.1
stage IV non-Hodgkin's lymphoma 9.1
CACP 9.1
Hodgkin's disease refractory 9.1
measurable disease 9.1
recurrent neuroblastoma 9.0
recurrent SCLC 8.9
acute stomatitis 8.9
acute stomatitis 8.9
Relative polycythaemia 8.9
refractory hairy cell leukemia 8.8
Disseminated aspergillosis 8.7
adult soft tissue sarcoma 8.7
Granulocytosis 8.6
FAB L2 8.6
relapsed CML 8.5
Neutropenic sepsis 8.5
recurrent retinoblastoma 8.5
hand-foot syndrome 8.4
Non-occlusive mesenteric ischemia 8.4
recurrent cervical cancer 8.4
more...
Symptom
Chills and fever 10.1
Generalized fatigue 9.8
nausea and vomiting 8.1
Reticulocytosis 7.8
Flu-like symptoms 7.6
diminished hearing 7.3
nausea 6.7
testicular pain 6.5
asthenia 6.4
GI irritation 6.4
vomiting 6.3
Skin symptoms 6.3
lassitude 6.2
onychomadesis 5.9
rigors 5.9
anorexia 5.7
Cushingoid 5.6
Cushingoid 5.6
bone pain 5.5
periorbital edema 5.4
muscle cramps 5.4
diarrhea 5.3
dark urine 5.3
chills 5.2
generalized rash 5.2
myalgia 5.1
meningism 5.0
Flare 4.9
Gastrointestinal symptoms 4.8
fever of unknown origin 4.7
inanition 4.6
Ill 4.5
tenesmus 4.5
anal pain 4.5
paresthesia 4.4
lethargy 4.4
hyperesthesia 4.3
splenomegaly 4.3
fatigue 4.3
non-productive cough 4.3
more...
Drug
5-Oxo-L-Norleucine 12.4
Trimetrexate glucuronate 11.4
Emitefur 11.4
Eniluracil 10.8
Eniluracil 10.8
Romurtide 10.8
Etoposide phosphate 10.7
Edatrexate 10.6
Ganciclovir sodium 10.4
Leridistim 10.4
Ifex 10.4
Stilphostrol 10.1
Mesnex 10.1
Nartograstim 10.1
Stilphostrol 10.1
Teroxirone 10.1
Topotecan hydrochloride 10.1
Ormaplatin 9.7
Indisulam 9.6
Adozelesin 9.6
Menogaril 9.4
Rubitecan 9.4
Ibritumomab tiuxetan 9.3
Satraplatin 9.2
Carbetimer 9.1
Isovorin 8.9
Novantrone 8.9
Alimta 8.9
Temodal 8.9
Vindesine 8.9
Paraplatin 8.8
Teniposide 8.8
Vindesine 8.8
Lonafarnib 8.8
Quadramet 8.7
Doxifluridine 8.7
Fludarabine 8.6
Leukine 8.5
Idarubicin 8.5
Maribavir 8.5
more...
Enzyme
DHAD 9.2
thiopurine methyltransferase 9.0
EC 3.6.1.19 8.9
MTD 7.0
TUT 6.7
GMP synthase 6.6
dihydropyrimidine dehydrogenase 6.4
dihydropyrimidine dehydrogenase 6.2
asparaginase 6.1
deoxycytidine deaminase 6.0
carboxypeptidase G2 5.9
cytidine deaminase 5.8
deoxycytidine kinase 5.7
farnesyltransferase 5.5
CTP synthase 5.5
thymidine phosphorylase 5.4
thymidylate synthase 5.3
deoxyguanosine kinase 5.2
glycinamide ribonucleotide transformylase 5.2
CEP 5.2
inosine triphosphatase 5.1
dihydrofolate reductase 5.0
farnesyltransferase 5.0
dihydroorotate dehydrogenase 5.0
dihydroorotate dehydrogenase 5.0
adenylosuccinate synthetase 4.7
aspartate transcarbamylase 4.6
aminopeptidase B 4.6
CEP 4.6
lactic acid dehydrogenase 4.6
ribonucleotide reductase 4.5
methylthioadenosine phosphorylase 4.5
ribonucleotide reductase 4.5
lactic acid dehydrogenase 4.5
BMT 4.5
adenosine deaminase 4.4
adenosine deaminase 4.4
orotate phosphoribosyltransferase 4.0
Fpg protein 4.0
topoisomerase 4.0
more...
Compound
Spiroplatin 12.4
Mesuol 11.4
Estramustine phosphate sodium 11.4
Asaley 11.4
Fazarabine 11.0
Baker's Antifol 10.8
Fazarabine 10.8
Fludarabine phosphate 10.6
Pyrazine diazohydroxide 10.6
PalmO-ara-C 10.4
C9H8O2 10.4
C9H8O2 10.4
DHAC 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
C9H8O2 10.4
AZQ 10.2
Trimetrexate 10.1
Stilphostrol 10.1
Pyrazine diazohydroxide 9.9
PCNU 9.9
C9H8O2 9.8
Deoxydoxorubicin 9.8
Indicine 9.8
Foscarnet sodium 9.8
C9H8O2 9.8
C9H8O2 9.8
Homoharringtonine 9.7
C9H8O2 9.6
7-OMEN 9.6
C9H8O2 9.6
AAFC 9.6
GANU 9.6
Topotecan 9.4
C5H12N2 9.4
GANU 9.3
more...