Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0854467 (myelosuppression)
5,932 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 333
granulocyte colony-stimulating factor 220
non-Hodgkin's lymphoma 197
granulocyte 194
CSF 110
cytokine 107
G-CSF 105
interferon 100
erythroid 89
hemoglobin 89
granulocyte-macrophage 85
lymphoid 84
granulocyte-macrophage colony-stimulating factor 75
GM-CSF 74
Mol 57
AML 53
erythropoietin 53
ara 53
IFN 49
topoisomerase I 46
CD34 45
CCNU 45
megakaryocyte 43
CHOP 43
thiopurine methyltransferase 41
tyrosine kinase 39
CD4 38
osteosarcoma 37
macrophage colony-stimulating factor 36
CD20 35
thrombopoietin 35
She 34
ALL 34
dihydrofolate reductase 34
IL-3 34
thymus 33
IL-6 33
P-glycoprotein 32
stem cell factor 31
thiopurine S-methyltransferase 28
more...
Disease
myelosuppression 5932
cancer 2283
tumor 862
thrombocytopenia 753
neutropenia 724
breast cancer 386
leukopenia 385
leukemia 361
lymphoma 358
acute myeloid leukemia 327
carcinoma 311
anemia 276
lung cancer 254
non-small cell lung cancer 228
non-Hodgkin's lymphoma 228
stomatitis 222
Hodgkin's disease 211
metastases 202
sepsis 192
ovarian cancer 191
acute lymphoblastic leukemia 174
metastatic breast cancer 169
sepsis 163
multiple myeloma 154
acute leukemia 146
melanoma 143
adenocarcinoma 140
chronic myeloid leukemia 140
myelodysplastic syndrome 135
small cell lung cancer 133
squamous cell carcinoma 128
peripheral neuropathy 127
colorectal cancer 119
agranulocytosis 118
rash 114
chronic lymphocytic leukemia 114
epithelial ovarian cancer 109
pneumonia 109
lung carcinoma 104
chronic lymphocytic leukemia 94
more...
Symptom
nausea and vomiting 481
vomiting 481
nausea 460
diarrhea 409
fatigue 193
anorexia 137
pain 98
headache 52
Ill 48
asthenia 43
myalgia 41
splenomegaly 37
dyspnea 30
chills 30
constipation 30
seizures 30
bone pain 26
weakness 26
erythema 25
abdominal pain 25
sleepiness 24
lethargy 22
paresthesia 20
dizziness 15
flushing 15
arthralgia 14
chest pain 12
ataxia 12
fever of unknown origin 10
respiratory distress 10
anesthesia 9
rigors 9
discomfort 8
discomfort 8
tinnitus 8
cough 7
muscle cramps 7
exhaustion 6
testicular pain 6
dysuria 6
more...
Drug
CSF 174
Adriamycin 121
G-CSF 118
CTX 68
Taxol 66
Etoposide 64
TTC 52
Docetaxel 42
CPT-11 35
Fludarabine 33
CTX 26
CTX 26
Irinotecan 25
Lenalidomide 23
anti-CD33 20
Vinorelbine 20
Dermatol 19
Novantrone 18
Leucovorin 18
-deoxyadenosine 17
ADM 17
VCR 17
Pemetrexed 16
Filgrastim 15
Filgrastim 15
Taxotere 15
Rituximab 15
IL-2 15
Imatinib 15
Amifostine 14
Idarubicin 14
Gleevec 12
MDS 11
Cremophor EL 11
Oxaliplatin 10
Vindesine 10
Vindesine 10
GEO 9
Dasatinib 9
BLM 9
more...
Enzyme
ERK 57
focal adhesion kinase 56
thiopurine methyltransferase 51
dihydrofolate reductase 35
asparaginase 34
P-glycoprotein 32
alanine aminotransferase 31
topoisomerase 29
thymidylate synthase 27
alkaline phosphatase 27
topoisomerase 26
lactate dehydrogenase 26
adenosine deaminase 20
adenosine deaminase 20
aspartate aminotransferase 19
dihydropyrimidine dehydrogenase 17
catalase 15
superoxide dismutase 15
DNA methyltransferase 14
MTD 14
calcineurin 14
dihydropyrimidine dehydrogenase 13
ribonucleotide reductase 13
PARP 13
prostate-specific antigen 13
ribonucleotide reductase 12
caspase-1 11
BMT 11
peroxidase 11
MDR 10
cytidine deaminase 10
mitogen-activated protein kinase 9
AST 9
farnesyltransferase 9
farnesyltransferase 9
proteasome 9
thymidine phosphorylase 8
glutathione peroxidase 8
deoxycytidine kinase 7
creatine kinase 7
more...
Compound
Clin 778
Dec 391
DNA 297
Adriamycin 158
VP-16 157
5-FU 143
creatinine 130
DDP 117
CBDCA 115
CBDCA 115
Ara-C 81
BCNU 73
water 73
CTX 68
Paclitaxel 66
Ara-C 63
Gemcitabine 62
Gemcitabine 62
Methotrexate 59
ADR 55
Topotecan 51
Topotecan 51
Ifosfamide 51
phosphate 50
folinic acid 45
CCNU 45
pyrimidine 43
Mitoxantrone 43
pyrimidine 43
oxygen 40
Mitoxantrone 39
DIC 35
Docetaxel 35
CPT-11 34
iron 33
nitrogen 33
MMC 32
AZQ 29
sodium 28
Epirubicin 27
more...