Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0854467 (
myelosuppression
)
5,932
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
333
granulocyte colony-stimulating factor
220
non-Hodgkin's lymphoma
197
granulocyte
194
CSF
110
cytokine
107
G-CSF
105
interferon
100
erythroid
89
hemoglobin
89
granulocyte-macrophage
85
lymphoid
84
granulocyte-macrophage colony-stimulating factor
75
GM-CSF
74
Mol
57
AML
53
erythropoietin
53
ara
53
IFN
49
topoisomerase I
46
CD34
45
CCNU
45
megakaryocyte
43
CHOP
43
thiopurine methyltransferase
41
tyrosine kinase
39
CD4
38
osteosarcoma
37
macrophage colony-stimulating factor
36
CD20
35
thrombopoietin
35
She
34
ALL
34
dihydrofolate reductase
34
IL-3
34
thymus
33
IL-6
33
P-glycoprotein
32
stem cell factor
31
thiopurine S-methyltransferase
28
more...
Disease
myelosuppression
5932
cancer
2283
tumor
862
thrombocytopenia
753
neutropenia
724
breast cancer
386
leukopenia
385
leukemia
361
lymphoma
358
acute myeloid leukemia
327
carcinoma
311
anemia
276
lung cancer
254
non-small cell lung cancer
228
non-Hodgkin's lymphoma
228
stomatitis
222
Hodgkin's disease
211
metastases
202
sepsis
192
ovarian cancer
191
acute lymphoblastic leukemia
174
metastatic breast cancer
169
sepsis
163
multiple myeloma
154
acute leukemia
146
melanoma
143
adenocarcinoma
140
chronic myeloid leukemia
140
myelodysplastic syndrome
135
small cell lung cancer
133
squamous cell carcinoma
128
peripheral neuropathy
127
colorectal cancer
119
agranulocytosis
118
rash
114
chronic lymphocytic leukemia
114
epithelial ovarian cancer
109
pneumonia
109
lung carcinoma
104
chronic lymphocytic leukemia
94
more...
Symptom
nausea and vomiting
481
vomiting
481
nausea
460
diarrhea
409
fatigue
193
anorexia
137
pain
98
headache
52
Ill
48
asthenia
43
myalgia
41
splenomegaly
37
dyspnea
30
chills
30
constipation
30
seizures
30
bone pain
26
weakness
26
erythema
25
abdominal pain
25
sleepiness
24
lethargy
22
paresthesia
20
dizziness
15
flushing
15
arthralgia
14
chest pain
12
ataxia
12
fever of unknown origin
10
respiratory distress
10
anesthesia
9
rigors
9
discomfort
8
discomfort
8
tinnitus
8
cough
7
muscle cramps
7
exhaustion
6
testicular pain
6
dysuria
6
more...
Drug
CSF
174
Adriamycin
121
G-CSF
118
CTX
68
Taxol
66
Etoposide
64
TTC
52
Docetaxel
42
CPT-11
35
Fludarabine
33
CTX
26
CTX
26
Irinotecan
25
Lenalidomide
23
anti-CD33
20
Vinorelbine
20
Dermatol
19
Novantrone
18
Leucovorin
18
-deoxyadenosine
17
ADM
17
VCR
17
Pemetrexed
16
Filgrastim
15
Filgrastim
15
Taxotere
15
Rituximab
15
IL-2
15
Imatinib
15
Amifostine
14
Idarubicin
14
Gleevec
12
MDS
11
Cremophor EL
11
Oxaliplatin
10
Vindesine
10
Vindesine
10
GEO
9
Dasatinib
9
BLM
9
more...
Enzyme
ERK
57
focal adhesion kinase
56
thiopurine methyltransferase
51
dihydrofolate reductase
35
asparaginase
34
P-glycoprotein
32
alanine aminotransferase
31
topoisomerase
29
thymidylate synthase
27
alkaline phosphatase
27
topoisomerase
26
lactate dehydrogenase
26
adenosine deaminase
20
adenosine deaminase
20
aspartate aminotransferase
19
dihydropyrimidine dehydrogenase
17
catalase
15
superoxide dismutase
15
DNA methyltransferase
14
MTD
14
calcineurin
14
dihydropyrimidine dehydrogenase
13
ribonucleotide reductase
13
PARP
13
prostate-specific antigen
13
ribonucleotide reductase
12
caspase-1
11
BMT
11
peroxidase
11
MDR
10
cytidine deaminase
10
mitogen-activated protein kinase
9
AST
9
farnesyltransferase
9
farnesyltransferase
9
proteasome
9
thymidine phosphorylase
8
glutathione peroxidase
8
deoxycytidine kinase
7
creatine kinase
7
more...
Compound
Clin
778
Dec
391
DNA
297
Adriamycin
158
VP-16
157
5-FU
143
creatinine
130
DDP
117
CBDCA
115
CBDCA
115
Ara-C
81
BCNU
73
water
73
CTX
68
Paclitaxel
66
Ara-C
63
Gemcitabine
62
Gemcitabine
62
Methotrexate
59
ADR
55
Topotecan
51
Topotecan
51
Ifosfamide
51
phosphate
50
folinic acid
45
CCNU
45
pyrimidine
43
Mitoxantrone
43
pyrimidine
43
oxygen
40
Mitoxantrone
39
DIC
35
Docetaxel
35
CPT-11
34
iron
33
nitrogen
33
MMC
32
AZQ
29
sodium
28
Epirubicin
27
more...