Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0851341 (
infestation
)
10,121
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
One hundred newborn swamp buffalo calves (Bubalis bubalis) from three villages in North-East Thailand were divided equally into treatment and control groups. Treated calves received two doses of a piperazine/thiabendazole mixture (196.6 and 50 mg/kg bodyweight respectively) at three, and again at ten weeks of age. Control calves received placebo treatments at the same times. Egg excretion rates for the roundworms Strongyloides papillosus and Toxocara vitulorum were recorded as high as 85% and 58% respectively during the first three months of life. During the trial period, four calves in the treated group died and one was treated for coccidiosis, compared to seven deaths and nine additional anthelmintic treatments required in the control group. All calves that either died or required additional anthelmintic treatment showed signs of severe enteritis, anorexia and
emaciation
that was attributed to parasitic
infestation
. Calves receiving emergency anthelmintic treatment all recovered uneventfully. All except four of the calves that died or became sick did so between 25 and 40 days post partum, with the remainder developing clinical signs of parasitosis before day 50. There was no difference in weight gains between treated and untreated calves over the trial period (16 weeks). Thus, the advantage of anthelmintic treatments as described at three and ten weeks of age in buffalo calves under village conditions was seen as a reduction in the combined morbidity/mortality rate from 32% to 10% (P less than 0.05). From the pattern of infection observed in this study it is suggested that further gains could be made by giving the second treatment at six (instead of ten) weeks of age, and by increasing the dosage of anthelmintic used.
...
PMID:Metaphylactic deworming program for buffalo calves (Bubalis bubalis) in North-East Thailand. 343 55
Observations were made on individual cases and on herds showing the effects of internal parasitism on the health and productivity of Toggenberg and Saanan goats. The clinical reactions varied markedly being influenced by the degree of
infestation
and duration of illness. Typical cases showed
emaciation
, anaemia, oedema, weakness and sometimes diarrhoea and death. Faecal analyses were dominated by strongyle egg counts which rose progressively throughout the study period. Overstocking led to some animals being at greater risk.
...
PMID:Internal parasitism in milk goats in Kenya. 648 5
Two immature female fin whales stranded on the Belgian and French coastlines, were examined post mortem. The main gross findings were massive parasitic
infestation
, associated with a large thrombus in one whale, and severe
emaciation
. Microscopical investigations revealed multinucleated syncytia with large intranuclear inclusion bodies in various tissues, and positive immunolabelling for morbillivirus antigens. Other evidence of morbillivirus infection was provided by the demonstration of specific viral structures in syncytia and in cell cultures, and the detection of neutralizing antibodies to canine distemper virus. To the authors>> knowledge, this is the first firm report of morbillivirus infection in baleen whales.
...
PMID:Pathological findings in two fin whales (Balaenoptera physalus) with evidence of morbillivirus infection. 1103 76
The environmental conditions and daily life in the ghettos of Europe during the holocaust are reviewed, and their effect on morbidity in different ghettos is scrutinized in an attempt to construct a typical morbidity profile. The outstanding characteristics were: crowding, shortage of basic necessities (such as food, clothing and medications), harsh environmental and sanitary conditions, inclement weather, poor personal hygiene, chronic undernutrition and malnutrition, physical and mental exhaustion. Morbidity was mainly due to infectious diseases, both endemic and epidemic outbreaks with high mortality, and high
infestation
rates of lice and other parasites. The dominant feature was "hunger disease" with its protean clinical expressions, endocine pathology, growth and development retardation in children, and amenorrhea and infertility among women of child-bearing age. Polyuria, nocturia and increased frequency of bowel movement were common. The typical presentation of a ghetto dweller was of extreme
emaciation
(a loss of up to 50% body weight); muscle weakness and skeletal abnormalities; pale, dry skin with excoriations; pedal edema; anxiety and nervousness; often goiter in children. Most of the inhabitants had some, or all, of those signs and symptoms (there were times when more than half the population was sick). This syndrome complex was termed "Ghetto Sickness" or "Ghetto Fatigue" (ghetto schwachkeit).
...
PMID:[Morbidity in the ghettos during the Holocaust]. 1201 93
Forty-six cats with clinical haemobartonellosis were studied; 75 per cent of the cats of known age were two-and-a-half years old or younger, 50 per cent were intact males and 19.5 per cent were castrated males. The predominant signs of the disease were tachypnoea, lethargy, depression, anorexia,
infestation
with fleas, pale mucous membranes, icterus,
emaciation
, dehydration, splenomegaly, anaemia, leucocytosis, increased activities of alanine aminotransferase and aspartate aminotransferase, and azotaemia. Thirty-eight per cent of the cats that were tested for feline leukaemia virus (FeLV) antigen were positive, and 22 per cent of those tested for feline immunodeficiency virus (FIV) antibodies were positive. The prevalence of both FeLV and FIV was much higher than in the general Israeli cat population. The cats infected with both Haemobartonella felis and FeLV had a significantly lower body temperature, were more anaemic and the mean cell volume of their erythrocytes was greater than in the cats with haemobartonellosis alone.
...
PMID:Retrospective study of 46 cases of feline haemobartonellosis in Israel and their relationships with FeLV and FIV infections. 1216 25
We report a case of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) with accompanying severe strongyloidiasis in a 52-year-old male. On admission, he showed drowsiness and
emaciation
with severe hyponatremia. We gave sodium (saline or salts) in an i.v. drip infusion and orally without improvement. A urinalysis and plasma osmotic pressure test indicated SIADH, therefore, treatment was changed to restrict his sodium intake. The hyponatremia gradually improved initially, but the appetite loss, nausea, and hyponatremia continued. Endoscopy revealed white patches on the stomach wall and histopathological examination revealed
infestation
of the mucosal epithelium with numerous Strongyloides stercoralis larvae. Ivermectin treatment was then initiated and the abdominal symptoms and hyponatremia gradually resolved. We carefully investigated the underlying cause of the SIADH, such as disease of the central nervous system, lung cancer, and other malignancies, but no abnormality or clear cause could be found. We concluded that the patient developed SIADH secondary to severe S. stercoralis infection.
...
PMID:Syndrome of inappropriate secretion of antidiuretic hormone associated with strongyloidiasis. 1753 72
Severe ventriculitis and
emaciation
caused by the
infestation
of the nematode Hadjelia truncata occurred in meat-type breeder rock pigeons (Columba livia) in southern and central California. Hadjelia truncata can infest several species of birds, although it has only been reported as pathogenic in pigeons. The factors that contribute to H. truncata pathogenicity are not known. The gross and microscopic pathology caused by the
infestation
of H. truncata in the ventriculus of pigeons and its morphological identification are presented.
...
PMID:Parasitic ventriculitis caused by Hadjelia truncata in California rock pigeons (Columba livia). 2236 12
In the austral summer of 2011, in the rural area of Villarrica county, southern Chile (39 degrees 16'S, 72 degrees 19'W), seven black-faced ibis juveniles (approximately 4 mo old) were observed in the field with weakness; they were unable to follow the group and struggling to take flight. Three of these birds were euthanatized, and complete necropsies were performed. Gross examination showed severe
infestation
with Colpocephalum trispinum and Ardeicola melanopis lice, moderate
emaciation
, pale musculature, bursal atrophy, and severe hemorrhagic enteritis due to a heavy proventricular and intestinal infection with Porrocaecum heteropterum nematodes. Fungal pneumonia and severe lymphoid depletion on thymus, spleen, and bursa were diagnosed by microscopic examination. Bursal lesions included apoptosis and necrosis of lymphoid cells, and several cystic follicles. The presence of severe lymphoid depletion associated with fungal pneumonia and severe external and internal parasite infections suggest the presence of an immunosuppressive syndrome in these birds that caused the death of several black-faced ibis juveniles in southern Chile during the summer of 2011.
...
PMID:Immunosuppressive syndrome in juvenile black-faced ibises (Theristicus melanopis melanopis) in southern Chile. 2305 Apr 84
Sarcoptic mange is a highly contagious skin disease that can have a devastating impact on affected wild mammal populations. There are notable variations in the clinical and pathologic picture of sarcoptic mange among species and among conspecifics. However, the origin of these variations is unclear. We propose a classification scheme for skin lesions associated with Sarcoptes scabiei
infestation
to provide a basis for a subsequent risk factor analysis. We conducted a case-control study focused on macroscopic and histologic examination of the skin, using 279 red foxes (Vulpes vulpes) found dead or shot in Switzerland between November 2004 and February 2006. All animals were submitted to gross necropsy following a detailed protocol. Selection criteria for cases (n=147) vs. controls (n=111) were the presence or absence of mange-like lesions, mite detection by isolation or histologic examination, and serologic testing for S. scabiei antibodies. Characteristic features of mange lesions were scored macroscopically in all foxes and histologically in 67 cases and 15 controls. We classified skin lesions and associated necropsy findings into three types of mange: A) early stage (n=45): focal-extensive skin lesions, thin crusts, mild to moderate alopecia, few mites, numerous eosinophils, and mild lymph node enlargement; B) hyperkeratotic, fatal form (n=86): generalized skin lesions, thick crusts with or without alopecia, foul odor, abundance of mites, numerous bacteria and yeasts, numerous lymphocytes and mast cells, severe lymph node enlargement, and
emaciation
; C) alopecic, healing form (n=16): focal lesions, no crusts, severe alopecia, hyperpigmentation and lichenification, absence of mites, mixed cell infiltration, and rare mild lymph node enlargement. We hypothesize that after stage A, the animal either enters stage B and dies, or stage C and survives, depending on largely unknown extrinsic or intrinsic factors affecting the host ability to control mite infestation.
...
PMID:Pathology of sarcoptic mange in red foxes (Vulpes vulpes): macroscopic and histologic characterization of three disease stages. 2330 75
The authors formally investigated a major international wildlife wholesaler and subsequently confiscated more than 26,400 nonhuman animals of 171 species and types. Approximately 80% of the nonhuman animals were identified as grossly sick, injured, or dead, with the remaining in suspected suboptimal condition. Almost 3,500 deceased or moribund animals (12% of stock), mostly reptiles, were being discarded on a weekly basis. Mortality during the 6-week "stock turnover" period was determined to be 72%. During a 10-day period after confiscation, mortality rates (including euthanasia for humane reasons) for the various taxa were 18% for invertebrates, 44.5% for amphibians, 41.6% for reptiles, and 5.5% for mammals. Causes of morbidity and mortality included cannibalism, crushing, dehydration,
emaciation
, hypothermic stress, infection, parasite
infestation
, starvation, overcrowding, stress/injuries, euthanasia on compassionate grounds, and undetermined causes. Contributing factors for disease and injury included poor hygiene; inadequate, unreliable, or inappropriate provision of food, water, heat, and humidity; presumed high levels of stress due to inappropriate housing leading to intraspecific aggression; absent or minimal environmental enrichment; and crowding. Risks for introduction of invasive species through escapes and/or spread of pathogens to naive populations also were identified.
...
PMID:Morbidity and mortality of invertebrates, amphibians, reptiles, and mammals at a major exotic companion animal wholesaler. 2487 63
1
2
Next >>