Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0851341 (infestation)
 10,121 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We had the opportunity of studying an epidemic of autochthonous amoebiasis occurring in the autumn of 1974 in a small town of 4000 inhabitants 30 km from Grenoble. Attention was originally attracted by the occurrence in this town of two cases of hepatic amoebiasis and one of intestinal amoebiasis identified by rectoscopy. Systematic investigations (coproctic examinations and serological tests for amoebiasis by indirect antibody fluorescence) were then carried out on everyone in the locality with digestive disorders which were possibly referable to amoebiasis, and on the other members of their families. A total number of 148 coproctic examinations were made and in two cases revealed the presence of vegetative forms of Entamoeba histolytica. In both cases the infestation provoked few symptoms (asthenia, vague abdominal discomfort, intermittent and apparently banal diarrhoea). On the other hand 20 out of 94 serological tests revealed positive results, 14 of which were equal to or greater than a titre of 1/100, a level at which all risks of non-specificity are virtually ruled out under our experimental conditions. Material reasons made it impossible to subject these cases to repeated faecal checks, but in two of them at least the rectoscopic appearances were very suggestive of subacute intestinal amoebiasis. Moreover, amoebic disease appears to be well confirmed by the results obtained among the patients as a whole by treatment with Metroinidazole. A variety of hypotheses on the origin of this epidemic have been put forward and then abandoned (market garden produce, receipt by certain families of exotic frut from overseas). In actual fact water seems to be the point of departure, for, although specimens of water taken at 7 different levels in the water supply system failed to reveal the presence of a single amoeba, bacteriological analyses during autumn 1974 showed signs of faecal contamination. The locality, which is situated at the foot of the Chartreuse massif, receives its water solely from springs but there is a holiday camp for the staff of an international airline situated above the main water catchment.
 ...
PMID:[Epidemic of autochthonous hepatic and intestinal amebiasis in a place near Grenoble]. 0 24

The effects of experimental infection of lambs with third stage Trichostrongylus larvae are described. Preceding diarrhea, disturbances in the motility of the reticulum, abomasum and jejunum were observed by electromyography. Disappearance of the migrating myoelectric complexes occurred about 24 h before diarrhea and was accompanied by a decrease in both the frequency of reticular contractions and of contractions propagated through the antro-duodenal junction. The significance of these findings is discussed and compared with natural infestation in the field.
 ...
PMID:[Electromyographic analysis of motor perturbations linked with gastrointestinal strongyloidiasis]. 13 60

An investigation of xerophthalmia was undertaken in four ecological zones in Cebu in the Philippines. One thousand seven hundred fifteen children aged 1 to 16 years were examined in 12 barrios. Clinical, biochemical and anthropometric data were collected from the children. Dietary and socioeconomic information was obtained from the households. Multivariate statistical techniques were used to examine factors possibly associated with xerophthalmia. Of children 47% had deficient or low serum vitamin A levels and 4.5% had clinical signs of xerophthalmia. Approximately 2% had both low serum vitamin A levels and clinical eye signs and were then defined as having active xerophthalmia. Vitamin A deficiency was more prevalent in males than females. Xerophthalmia was most common in the 4 to 6 year old age group. Diarrhea, roundworm infestation and measles were not positively correlated with xerophthalmia but whooping cough and tuberculosis were. Low intakes of carotene and vitamin A were associated with xerophthalmia but protein and fat intakes were not. A higher incidence of xerophthalmia occurred in children of working than nonworking mothers. Data on home production and use of vegetables and fruits are presented. The results of this study are being used to introduce three alternate intervention strategies to control xerophthalmia.
 ...
PMID:Vitamin A deficiency in the Philippines: a study of xerophthalmia in Cebu. 62 57

The association of clubbing, growth retardation, pallor, abdominal distension, and prolonged bloody diarrhoea with whipworm (Trichuris trichiura) infestation is described and discussed. Failure to recognise this association leads to misdiagnosis and unnecessary investigation.
 ...
PMID:Clubbing and whipworm infestation. 66 56

Twenty-eight Friesland calves were infested at 7 to 11 months of age with 5 000-45 OOO cercariae of Schistosoma mattheei. At 7 to 8 weeks post-infestation the majority developed an acute intestinal syndrome characterised by diarrhoea or dysentery, anorexia and loss of condition, from which they recovered spontansously. The severity and duration of illness was proportional to the level of infestation. Two heavily infested animals on a low plan of nutrition developed a subacute syndrome in which the initial acute disease was succeeded by prolonged unthriftiness, without diarrhoea, from which recovery occurred when the nutritional status was improved. Both acute and subacute forms of the syndrome were encountered in natural outbreaks.
 ...
PMID:Schistosoma mettheei infestation in the ox: the intestinal syndrome. 87 50

The use of secretin to facilitate the demonstration of Giardia lamblia in duodenal juice was studied in children under investigation for chronic diarrhoea. 30 children aged 3 months to 13 years, whose stools were negative for G. lamblia, were studied. G. lamblia was demonstrable in a sample of duodenal juice in 1 of the 30 children before an intravenous injection of secretin (1 or 2 mg/kg), but in 9 of the 30 children after secretin. It is concluded that examination of duodenal juice after secretin stimulus is an effective method of showing giardial infestation.
 ...
PMID:Duodenal intubation with secretin stimulus for diagnosis of giardiasis. 87 38

A patient is presented who developed acute life-threatening diarrhoea due to infestation with Giardia lamblia. We propose that the severity of the illness may have been related to hypochlorhydria following gastric surgery.
 ...
PMID:Giardiasis following gastric surgery. 107 81

Giardia lamblia infestation can cause severe diarrhea and malabsorption, and the diagnosis is usually made by identification of cysts in the feces, but small intestinal biopsy or smears may be required. A wide spectrum of roentgen changes may be seen. In patients with a normal immune status, the small bowel is normal or shows an inflammatory bowel disease pattern. Eradication of the parasite reverses these changes. In some patients with IgA deficiency, nodular lymphoid hyperplasia occurs, and this is usually not reversible. Other patients with hypogammaglobulinemia or dysgammaglobulinemia and giardiasis may show a sprue pattern. This pattern most often persists after eradication of the parasite. Although the triad of giardiasis, IgA deficiency, and nodular lymphoid hyperplasia has a particularly high association, these, together with diarrhea, malabsorption, and various altered immune states may occur in any combination.
 ...
PMID:Current perspectives on giardiasis. 110 21

Young people constitute 46% of the population in the West Bank of Israel and 48% in the Gaza Strip with a rate of growth of 3.1% and 3.4%, respectively. Their living conditions are characterized by lack of sanitation, shortage of water (especially in comparison to Israel proper), unemployment, curfews and closing of schools during tense periods by the military authorities as collective punishment for incidents. Since 1967, Israel has controlled and administered the health care service in these territories. Since the 1980s dilution of pediatric care has been documented in the West Bank: there were no special services available for treating 200 Palestinian children with malignant tumors. Decentralization has resulted in only 1 project around Hebron and in 10 villages in the vicinity of Jerico when the objective was to reach by community-based service 200 villages in want of out patient child and maternal health services. Official Israeli sources indicated a greatly reduced infant mortality by 1987; to below 30/1000, but other sources indicated 91/1000 live births under 1 year of age and 120/1000 under 3 years of age. These rates are contrasted with 18/1000 among the Palestinian community in Israel and 12/1000 among the Hebrew population itself. Infant mortality and morbidity is caused by diarrheal and respiratory diseases. A high incidence of dental caries and dermatological and intestinal parasitological problems have also been encountered by an Italian medical team. In 3 villages studied there was a 32% incidence of intestinal parasitic infection in children up to 3 years of age; 26% giardia lamblia, 3% entamoeba histolytica, 3% hymenolepis nana, 3% entamoeba coli, and 1% ascaris lumbricoides. 3% had double infestation. In 1990 the UN registered 329 cases of measles: 252 in Syria, 45 in Lebanon, and 122 in Gaza. 153 of these had been vaccinated, and in Gaza there had been a measles vaccination campaign. The incidence of diseases dependent on the environment have decreased: infantile diarrhea, infectious hepatitis, and intestinal fever. The problems of public health can only be resolved by an independent national authority.
 ...
PMID:[The living and health conditions of Palestinian children]. 129 73

A presumptive diagnosis of buttercup toxicosis with photosensitization secondary to hepatotoxicity was made in an 18-mo-old Charolais heifer. The differential diagnosis included salmonellosis, aflatoxicosis, bovine virus diarrhea, internal parasite infestation, and plant toxicosis with either primary or secondary photosensitization. All these possibilities were excluded except buttercup toxicosis with photosensitization secondary to hepatotoxicity. While this diagnosis was not absolutely confirmed, it was the most likely cause of the disease and raised the intriguing possibility that protoanemonin, buttercup's toxic principle, is hepatotoxic.
 ...
PMID:Suspected buttercup (Ranunculus bulbosus) toxicosis with secondary photosensitization in a Charolais heifer. 160 96


1 2 3 4 5 6 7 8 9 10 Next >>