Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0851341 (infestation)
 10,121 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The incidence of psammoma bodies in cervical smears and of opportunistic infections by actinomyces or ameba is reported in 15,000 patients using IUDs. During the 1972-1978 period, cervical smears from 440,550 women were examined. Of these, 14,980 wore an IUD. 88% of the patients with an IUD were fitted with Multiload Cu250, 8% had Copper T and 4% Lippes Loop. Smears from 7500 patients using oral contraceptives (OCs) and from 7500 patients using no contraception were used as control groups. The smears from the women wearing an IUD were screened and the following were recorded: psammoma bodies, hematoidin crystals, trichomonads, ameba and actinomyces. There were significant differences between IUD users and the control groups in the occurrence of psammoma bodies, ameba and actinomyces but not in trichomonads or hematoidin crystals. Psammoma bodies were found in 1.4% of the cases and actinomyces in 3.7%. Only 1 patient had a transient amebic infestation. The occurrence of psammoma bodies and actinomyces was proportional to duration of IUD use. Most cases were found after 2 years use. The actinomyces were easily identifiable with the Gram stain. The wise course is to make a Gram-stained cervical smear in all women after 2 years of IUD use in order to detect the presence of genital actinomyces.
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PMID:Psammoma bodies and some opportunistic infections detected in cervical smears of women fitted with an IUD. 1227 9