Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0851341 (infestation)
 10,121 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This investigation was carried out to evaluate the prevalence of vaginal trichomoniasis in relation to subjects' age, marital status, parity, pregnancy and the intensity of the discharge. The subjects were 613 Sudanese women presenting with vaginal discharge, investigated at a sexually transmitted disease clinic in Khartoum. On the day of examination, a full history was taken, and particular attention was paid to the duration and amount of any vaginal discharge, as well as to past antitrichomonal therapy. 123 (20.1%) of the patients examined were found infested with T. vaginalis. The duration of the vaginal discharge ranged from a few days to 10 years. The discharge in parasitized women was copious in 30 cases (24.2%), moderate in 42.3%, scanty in 26.9% and absent in 6.6% of the cases. In non-parasitized patients, the discharge was copious in 8.1% of cases. The frequency of vaginal trichomoniasis was 20.1% in all patients examined. Trichomonal infestation was predominant in the age groups 16-19 years (27.1%) and 46 years and above (27%), thus confirming reports that trichomonal infestation may occur during the period of greatest sexual activitiy, as well as at older ages. The highest frequency was among divorced women (35.9%), followed by widowed women (29.4%) and may be related to promiscuity and to variety of sexual contacts. 16.3% of the pregnant women investigated were found harboring the parasite; there was no significant difference in the parity of parasitized (81.6%) and non-parasitized patients (82.3%). Association of T. vaginalis with gonorrhea and candidiasis was significant, though this did not modify the symptoms and signs of trichomoniasis. The results suggest that there is no significant difference between whites and dark-skinned peoples.
 ...
PMID:Vaginal trichomoniasis at a sexually transmitted disease clinic at Khartoum. 404 3

The occurrence of cervical cancer among 511 inmates of the Detroit H ouse of Correction was investigated. 30% of the women were prostitutes, 82.6% had trichomonas infestation, 15.5% had syphilis, and 5.3% had gonorrhea. 3.7% of the women were diagnosed as having cancer of the cervix, a rate that was 4 times higher than in a matched control group. Sexual activity of the prisoners, on the average, began 2.8 years earlier than it did for controls. It is concluded that the initiation of coitus at an early age and promiscuity are the primary etiologic factors associated with cervical cancer.
 ...
PMID:Epidemiology of cervical cancer: study of a prison population. 563 81

Certain enteric ailments are particularly common among homosexual men. They are primarily infectious diseases and include not only such common venereal diseases as gonorrhea and syphilis but also infections not usually regarded as being sexually transmitted. Among the latter are shigellosis, salmonellosis, giardiasis, and amebiasis. Patients' symptoms are non-specific and seldom helpful in diagnosing particular diseases. The practitioner must be prepared to identify a number of infections with similar presentations that may occur singly or together in gay men. Gonorrhea is probably the most common bacterial infection in gay men. Carriage rates as high as 50% have been reported, and extra-genital carriage is common; this necessitates culturing the urethra, rectum, and pharynx. Procaine penicillin G is the treatment of choice for most patients; spectinomycin is probably the drug of choice in penicillin-sensitive patients. In contrast to other venereal diseases, syphilis may have a characteristic protoscopic presentation. Benzathine penicillin G is the treatment of choice for most patients. Lymphogranuloma venereum causes penile lesions and inguinal lymphadenitis in heterosexual men, whereas homosexual men are more prone to proctitis. The disease may mimic Crohn's disease. Recommended treatment includes tetracycline or sulfamethoxazole-trimethoprim. Shigellosis usually presents as an acute diarrheal illness. Patients generally require only supportive treatment with fluids. Herpes simplex viral infection is difficult to diagnose and has several different presentations, including lumbosacral radiculomyelopathy. Symptomatic treatment with sitz baths, anesthetic ointment, and analgesics is recommended. Venereal warts are believed to be caused by the same virus that causes verrucous warts; they are usually found in the anal canal or around the anal orifice. They are commonly treated with 25% podophyllin solution. Parasitic infections include giardiasis, amebiasis, and pinworm infections. Metronidazole may be used in the treatment of symptomatic giardiasis and amebiasis, but it is not approved for the former indication; quinacrine is approved for giardiasis. Pinworm infestation may be treated with pyrantel pamoate or mebendazole. Cure of enteric diseases in homosexual men must be documented.
 ...
PMID:Enteric diseases of homosexual men. 676 90

Fifty-four premenarcheal patients (median age 5.8 years) with symptoms or signs of vulvovaginitis were studied, and the results of cultures of vaginal secretions were compared with those from an age-matched control group. Vaginal discharge was found on examination in 24 of 42 patients with a complaint of discharge, and in two of 12 patients without a complaint of discharge. Convincing evidence of bacterial or monilial infection was found in 14 of the 26 patients with discharge on examination, but in none of the 28 patients without discharge (P less than .001). In the latter group pinworm infestation was present in one patient. Moniliasis occurred exclusively in girls who were pubertal (P less than .001). Four patients were found to have gonorrhea. No patient appeared to have symptoms or signs caused by Bacteroides sp, Chlamydia trachomatis, viruses, or Trichomonas vaginalis. Noninfectious causes were identified in four patients with and 13 without discharge (P less than .025); the most common cause was poor hygiene, implicated in six patients. Bubble bath use was implicated in only one patient. In 22 patients, no specific cause could be identified. All patients with poor hygiene as the only cause, and most with no demonstrable etiology, recovered after being advised to institute improved perineal hygiene. Patients with vaginal discharge are likely to have specific infections, and therefore cultures should be taken, in particular for Neisseria gonorrhoeae. Genital pruritus in prepubertal girls has little or no etiologic specificity, but in pubertal girls with vaginal discharge it suggests the presence of monilial vaginitis.
 ...
PMID:Vulvovaginitis in premenarcheal girls: clinical features and diagnostic evaluation. 709 84