Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0851184 (thinning)
11,252 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 710
collagen 426
MRI 350
Mol 217
ACS 143
dilute 107
axonal 104
OCT 103
She 79
NMR 75
cytokine 55
TEM 51
insulin 50
elastin 47
matrix metalloproteinase 41
lamp 40
Alport syndrome 39
X-linked 36
endoplasmic reticulum 35
alkaline phosphatase 34
DDT 34
caspase-3 33
vascular endothelial growth factor 33
hole 32
PEG 32
gut 30
ATP 29
ash 27
albumin 26
ATPase 26
TNF 25
mucin 25
olfactory 25
hemoglobin 25
proteoglycan 25
DSC 24
SDS 24
glial fibrillary acidic protein 24
type I collagen 24
asymmetrical 24
rhodopsin 23
IL-6 23
p53 22
AFM 22
thymus 22
CSF 22
CO2 21
Pseudomonas 21
Pol 21
tumor necrosis factor 21
IgA 21
ANOVA 20
VEGF 20
Rec 19
casein 19
parathyroid hormone 19
fibronectin 19
osteogenic 18
superoxide dismutase 18
keratin 18
PEO 18
MMP-9 18
ERG 17
PBS 17
osteocalcin 17
glycoprotein 17
polypeptide 17
renin 17
BMD 16
COL4A3 16
Mal 16
MMP-2 16
fused 16
smooth muscle actin 16
Hip 16
CA1 16
amylase 15
COL4A4 15
corneal dystrophy 15
membrane protein 15
Poly 15
cardiac muscle 15
amyloid precursor protein 15
SMA 15
myosin 14
glucan 14
vimentin 14
strabismus 14
angiotensin II 14
serum albumin 14
osteosarcoma 13
peroxidase 13
Bot 13
estrogen receptor 13
collagenase 13
apolipoprotein E 13
PCB 13
EPA 13
Ki-67 13
Rho 12
Men 12
cage 12
lacrimal 12
ferritin 12
IPL 12
chronic renal failure 12
CA3 12
Bcl-2 12
lysozyme 12
membrane-bound 12
hairless 11
catenin 11
growth hormone 11
lipopolysaccharide 11
CD4 11
tyrosine hydroxylase 11
catalase 11
lymphoid 11
interleukin-6 10
APOE 10
IL-10 10
GBM 10
reserved 10
phosphodiesterase 10
desmin 10
MMP-1 10
CD8 10
RPE 10
insulin-like growth factor 10
Gen 10
brush border 10
metalloproteinase 10
calbindin 9
thrombin 9
E11 9
IFN 9
glucocorticoid receptor 9
glucosamine 9
neurofibromatosis 9
PLA 9
creatine kinase 9
reductase 9
TGF-beta 9
MMP-3 9
SOD 8
PDGF 8
synuclein 8
extracellular signal-regulated kinase 8
antioxidant enzyme 8
C18 8
C-reactive protein 8
long chain 8
IgE 8
involucrin 8
IL-4 8
fibrinogen 8
calcium channel 8
GSH 8
calcitonin 8
E14 8
more...
Disease
cornea 324
Alzheimer's disease 224
myocardial infarction 216
keratoconus 196
glaucoma 169
tumor 166
ischemia 153
osteoporosis 151
cognitive impairment 146
heart failure 133
diabetes 131
dementia 125
cancer 125
hypertension 122
intraocular pressure 110
myopia 105
depression 104
dysplasia 102
osteoarthritis 96
cataract 94
plaque 93
schizophrenia 90
Parkinson's disease 80
astigmatism 79
neuropathy 78
blindness 78
atherosclerosis 77
stroke 76
cardiomyopathy 75
multiple sclerosis 71
hydrocephalus 67
SEM 67
acute myocardial infarction 65
retinopathy 65
Alport syndrome 64
sclera 61
dilated cardiomyopathy 61
brain atrophy 59
renal disease 56
hypertrophic cardiomyopathy 52
myocardial ischemia 52
proteinuria 52
TEM 51
TEM 51
congestive heart failure 50
cold 49
keratitis 49
ventricular hypertrophy 48
HIV 48
diabetic retinopathy 47
macular degeneration 47
optic neuritis 46
epilepsy 46
ventricular dilatation 45
autism 43
West 42
psoriasis 41
prolapse 40
arthritis 40
psychosis 40
rheumatoid arthritis 40
coronary artery disease 39
retinitis pigmentosa 39
retinal detachment 38
coronary occlusion 35
uterus 35
developmental delay 34
Anterior 34
conjunctiva 34
ash 33
sarcoidosis 31
Best 31
renal failure 30
deafness 29
cardiovascular disease 29
refractive error 29
heart disease 29
obesity 28
pruritus 28
mitral regurgitation 28
AGA 27
optic atrophy 27
scotoma 27
breast cancer 27
amyotrophic lateral sclerosis 27
fits 26
hyperkeratosis 25
myocarditis 25
SDS 25
type 2 diabetes 24
mental retardation 24
dehydration 24
bone disease 24
keratopathy 24
malnutrition 23
mental retardation 23
glomerulonephritis 23
corneal ulcer 23
Retina 22
dysphagia 22
major depressive disorder 22
Retina 22
hydronephrosis 22
megalocornea 22
squamous cell carcinoma 21
systemic lupus erythematosus 21
spastic paraplegia 20
Huntington's disease 20
hyperparathyroidism 20
AIDS 20
melanoma 20
Cornea 19
macular edema 19
aphasia 19
Cornea 19
scleroderma 19
scleritis 19
strabismus 19
carcinoma 19
immunodeficiency 19
glomerulosclerosis 19
hyperglycemia 19
telangiectasia 18
vascular disease 18
epiphysis 18
skin disease 18
parakeratosis 18
scoliosis 17
varices 17
chronic renal failure 17
BMD 17
hernia 17
PSS 17
muscular atrophy 17
corneal degeneration 17
asthma 17
type 1 diabetes 16
vasculitis 16
nystagmus 16
pathological fracture 16
bipolar disorder 16
Autism 16
IgA nephropathy 16
pulmonary hypertension 16
peripheral neuropathy 16
atrioventricular block 16
tumor growth 16
lung disease 16
conjunctivitis 15
virus infection 15
connective tissue disease 15
uveitis 15
dermatitis 15
corneal dystrophy 15
Down syndrome 14
Evans 14
nephrotic syndrome 14
rare disease 14
abdominal aortic aneurysm 14
hypogonadism 14
more...
Symptom
thinning 11252
pain 170
collapse 79
weakness 71
seizures 49
ataxia 41
anesthesia 41
headache 32
dry eye 32
hypotonia 27
discomfort 22
fatigue 22
discomfort 21
spasticity 21
diarrhea 21
erythema 20
chest pain 19
tremor 18
pallor 18
dyspnea 17
asynergy 16
abdominal pain 15
blurred vision 15
functional recovery 15
agitation 15
starvation 14
paraparesis 13
nausea 13
cerebellar ataxia 12
photophobia 12
paresis 12
vomiting 12
angina 11
acidity 11
regurgitation 11
cough 10
syncope 10
distraction 9
respiratory distress 9
spasm 9
constipation 9
knee pain 9
hyperoxia 9
hemiplegia 8
dizziness 8
polyuria 8
dysarthria 7
dystonia 7
dysuria 7
apathy 7
vertigo 6
skin damage 6
shoulder pain 6
arthralgia 6
sleepiness 5
memory loss 5
back pain 5
fasciculation 5
flank pain 5
hypothermia 5
epigastric pain 5
dry skin 5
low back pain 4
abiotrophy 4
nausea and vomiting 4
numbness 4
rhinorrhea 4
tinnitus 4
heel pain 4
exertional dyspnea 4
stigma 4
bone pain 4
eye pain 4
hemoptysis 4
hepatomegaly 4
muscle stiffness 4
visual hallucination 4
hip pain 3
nasal discharge 3
hypercapnia 3
exhaustion 3
blepharospasm 3
Visual symptoms 3
pachyonychia 3
overweight 3
polydipsia 3
hot flushes 3
urinary frequency 3
analgesia 3
ataxic gait 3
Decreased activity 3
clubbing 3
intention tremor 3
anorexia 3
anosmia 3
asthenia 3
bradykinesia 3
koilonychia 3
Prodrome 3
physical appearance 3
Wind 3
cyanosis 3
myalgia 3
atypical chest pain 3
neck pain 3
tachypnea 3
onychomadesis 2
neurological disability 2
masculinization 2
tense 2
Burning 2
shortness of breath 2
leg pain 2
tingling 2
Depressive symptoms 2
incoordination 2
emaciation 2
myoclonus 2
abnormal gait 2
acute abdomen 2
joint stiffness 2
ophthalmoplegia 2
limb pain 2
irregular bleeding 2
paresthesia 2
skin irritation 2
Dellen 2
pelvic pain 2
loss of balance 2
generalized erythema 2
sciatica 2
twitching 2
eds 2
ENT 2
Ill 2
hepatosplenomegaly 2
hunger 1
partial seizure 1
Skin thickening 1
Fluctuation 1
Catch 1
Bitot's spots 1
leg cramps 1
Scratch 1
photopsia 1
lethargy 1
tonic seizure 1
dysosmia 1
athetosis 1
bitter taste 1
Welt 1
dysesthesia 1
metamorphopsia 1
meningism 1
lassitude 1
clonus 1
thigh pain 1
HSA 1
cachexia 1
stomach cramps 1
more...
Drug
Dermatol 197
Cardiovasc 95
Leaf 27
lysine 26
CSF 23
nitroglycerin 21
Fluorescein 17
vitamin E 15
ascorbate 15
MAP 14
Fluorescein 14
Gel 13
PCB 13
Monit 13
Frontal 12
lactose 9
HCH 8
Biopolymers 8
Depo-Provera 8
PTH 7
ROS 7
Xanthan gum 7
NADH 7
Gelatin 7
SiO2 7
CTX 6
balanced salt solution 6
EE2 6
ABC 5
Triclosan 5
Clobetasol propionate 5
PPA 5
Ringer's solution 5
IL-2 5
ROC 5
Spectrum 5
TiO2 5
Norplant 4
Gramicidin 4
DMSA 4
Retinoic acid 4
Herceptin 4
Spectrum 4
citric acid 4
Camp 4
Prednisolone farnesylate 4
Guar gum 4
Dial 4
Meditec 3
Azithromycin 3
Indomethacin 3
Glutathione 3
Ethanol 3
Sodium alginate 3
TAC 3
CTX 3
EPA 3
Vitamin A 3
Phosphatidylserine 3
CaCl2 3
caffeine 3
CTX 3
Zoladex 3
CaCl2 3
Prednisolone 3
CaCl2 3
Bevacizumab 3
ETA 3
Mutagen 3
Carbopol 940 3
Norplant 3
Becotide 2
TAT 2
niacin 2
Tocopherol 2
Crixivan 2
Optison 2
Methylprednisolone 2
Galactose 2
Prednicarbate 2
Gelfoam 2
AZT 2
Dithranol 2
Asthma 2
Dakar 2
TES 2
Permalens 2
DHT 2
Wine 2
ZnO 2
Glycerol 2
Dihydrotestosterone 2
Ouabain 2
Infliximab 2
G-CSF 2
Clobetasone butyrate 2
DHT 2
Isotretinoin 2
AZT 2
Riboflavin 2
IL-1ra 2
Histamine 2
Poloxamer 188 2
Gastro 2
Levonorgestrel 2
Infliximab 2
Fluticasone propionate 2
Adriamycin 2
Silica 2
Carbopol 934 2
DNase I 2
Atropine 2
Crixivan 2
Finasteride 2
THA 2
Nitric Oxide 2
ENT 2
Zoladex 2
Anakinra 2
CDP 2
Zmax 2
Crixivan 2
Flixotide 1
Codeine 1
Viracept 1
Brij 96 1
Clodronate 1
DM1 1
Nasonex 1
ADM 1
Photofrin II 1
Vitamin E 1
DPA 1
Ipriflavone 1
Vitamin K 1
Lipiodol 1
Polysorbate 20 1
CFX 1
Pemetrexed 1
Theophylline 1
Donepezil 1
Lidofilcon A 1
Latanoprost 1
Psyllium husk 1
Tween 60 1
Indocyanine green 1
Pregabalin 1
Monensin 1
Femara 1
Irinotecan 1
RFP 1
Zein 1
Cortisporin 1
CEC 1
Bisacodyl 1
Indinavir 1
Ethane 1
Photofrin 1
Iohexol 1
AraC 1
more...
Enzyme
ACS 143
alkaline phosphatase 34
ERK 30
ATPase 26
collagenase 25
caspase-3 25
superoxide dismutase 24
mitogen-activated protein kinase 24
peroxidase 17
renin 17
protein kinase C 16
ACE 15
catalase 14
lysozyme 12
protein kinase 11
creatine kinase 10
focal adhesion kinase 10
tyrosine hydroxylase 10
phosphodiesterase 10
MMP-3 10
acetylcholinesterase 10
thrombin 8
hyaluronidase 8
alanine aminotransferase 8
acid phosphatase 8
elastase 8
trypsin 7
cellulase 7
transglutaminase 7
hyaluronidase 7
tyrosinase 7
lysyl oxidase 6
NO synthase 6
aspartate aminotransferase 6
cholinesterase 6
AMPK 5
reverse transcriptase 5
glutathione peroxidase 5
glutamine synthetase 5
proteasome 5
MMP 5
plasmin 5
matrix metalloproteinase 9 5
choline acetyltransferase 5
lactate dehydrogenase 5
CDR 4
urokinase-type plasminogen activator 4
carbonic anhydrase 4
lipase 4
matrix metalloproteinase 2 4
cytochrome oxidase 4
NQO1 4
pepsin 4
complex I 4
invertase 4
PARP 4
transcriptase 3
RNA polymerase 3
NOS 3
caspase-8 3
laccase 3
AMPK 3
tryptase 3
AMP-activated protein kinase 3
MAP 3
pyruvate dehydrogenase 3
calcineurin 3
hexosaminidase 3
glucocerebrosidase 3
prostaglandin synthetase 3
beta-galactosidase 3
adenylate cyclase 3
TdT 3
pyruvate dehydrogenase 3
pyruvate dehydrogenase 3
kallikrein 2
glutaminase 2
tissue kallikrein 2
angiotensin-converting enzyme 2 2
aconitase 2
glutathione S-transferase 2
chymase 2
glyceraldehyde-3-phosphate dehydrogenase 2
caspase-6 2
caspase-9 2
chitinase 2
caspase-6 2
interstitial collagenase 2
MDP 2
phosphatidylinositol 3-kinase 2
chymotrypsin 2
TPP 2
SOI 2
glucose oxidase 2
tissue plasminogen activator 2
phosphofructokinase 2
APC 2
MIP 2
phosphoenolpyruvate carboxykinase 2
pyruvate kinase 2
Mg2+-ATPase 2
leucine aminopeptidase 2
phosphoinositide 3-kinase 2
prolyl hydroxylase 2
granzyme B 2
phosphoenolpyruvate carboxykinase 2
urease 2
phospholipase A2 2
phosphoenolpyruvate carboxykinase 2
glyceraldehyde-3-phosphate dehydrogenase 2
phospholipase C 2
CD10 2
urease 2
TAT 2
NADPH oxidase 2
gamma-glutamyl transpeptidase 2
NADPH-diaphorase 2
sucrase 2
glyceraldehyde-3-phosphate dehydrogenase 2
NADPH oxidase 2
SPT 2
alcohol dehydrogenase 2
glyceraldehyde-3-phosphate dehydrogenase 2
glyceraldehyde-3-phosphate dehydrogenase 2
neuraminidase 2
cathepsin B 2
pectinase 2
sucrase-isomaltase 1
glutamate dehydrogenase 1
GAS 1
bromelain 1
UDP-glucose dehydrogenase 1
TSA 1
legumain 1
lactase 1
monoamine oxidase 1
cathepsin K 1
neutrophil elastase 1
ADH 1
PAL 1
BIS 1
CaMKII 1
DNA polymerase 1
myosin light chain kinase 1
PAT 1
amylomaltase 1
STR 1
PAL 1
BMA 1
polo-like kinase 1 1
UDP-glucuronosyltransferase 1
LDT 1
cdc2 1
CPT 1
DNA methyltransferase 1
CPT 1
lipoxygenase 1
GSK 1
PvdQ 1
TPP 1
more...
Compound
water 923
Dec 681
Clin 361
sodium 204
calcium 199
oxygen 189
DNA 172
Cardiol 172
ACS 143
ACS 143
glucose 136
hydrogen 104
phosphate 103
Retinal 100
salt 98
nitrogen 79
PEG 77
galactose 70
silicon 70
hyaluronic acid 66
sulfate 62
iron 60
ethanol 59
His 55
Cereb 53
TEM 53
PEG 52
DDE 51
phosphorus 48
urea 44
acetate 43
glutamate 39
potassium 39
silver 39
bromide 38
CO2 38
Collagen 38
glycerol 36
DDT 36
copper 33
creatinine 32
arginine 31
lysine 31
vitamin D 30
xylose 30
titanium 30
ATP 29
nitric oxide 26
dUTP 25
TNF 25
SDS 24
ammonium 23
zinc 22
cysteine 22
carbonate 21
iodine 19
acrylamide 19
Pluronic 19
hydroxide 19
retinoic acid 18
aluminum 18
leucine 18
nitrate 18
alanine 17
serine 17
BMD 16
aldehyde 16
mercury 16
nickel 16
NH2 15
POPC 15
aldehyde 14
sodium chloride 14
Starch 14
A 3 14
acetic acid 13
NIDA 13
DMSO 13
HCl 13
DMPC 13
Cellulose 13
tyrosine 13
Carbon 13
MAP 13
A 42 12
H2S 12
fluorine 12
hexadecane 12
DPPH 12
Neuronal 12
Optimal 11
Phe 11
DTPA 11
proline 11
EDTA 11
vinyl 11
EDTA 11
propylene glycol 10
acrylic acid 10
GSH 10
GSH 10
glutamic acid 10
Hematoxylin 10
propylene glycol 10
PAS 10
DPPC 9
PGE2 9
Phytol 9
hexane 9
molybdenum 9
DDD 9
Phytol 9
aldosterone 9
methionine 9
Tween 80 9
homocysteine 9
methanol 9
Adrenal 9
barium 9
DPPC 9
pyrene 8
retinol 8
manganese 8
sulfuric acid 8
PLA 8
methane 8
tryptophan 8
ASA 8
decane 8
tryptophan 8
cAMP 8
Estrogen 8
Alginate 8
formaldehyde 8
tryptophan 8
tryptophan 8
Isoproterenol 8
Salt 7
STZ 7
cGMP 7
NADH 7
Etretinate 7
ABA 7
Xanthan 7
SiO2 7
toluene 7
DSM 7
Hearts 7
Dexamethasone 7
Asp 7
MgO 7
Hearts 7
boron 7
cadmium 7
MIC 6
PPA 6
ADP 6
ammonia 6
Adriamycin 6
ABA 6
more...