Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0851184 (
thinning
)
11,252
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
710
collagen
426
MRI
350
Mol
217
ACS
143
dilute
107
axonal
104
OCT
103
She
79
NMR
75
cytokine
55
TEM
51
insulin
50
elastin
47
matrix metalloproteinase
41
lamp
40
Alport syndrome
39
X-linked
36
endoplasmic reticulum
35
alkaline phosphatase
34
DDT
34
caspase-3
33
vascular endothelial growth factor
33
hole
32
PEG
32
gut
30
ATP
29
ash
27
albumin
26
ATPase
26
TNF
25
mucin
25
olfactory
25
hemoglobin
25
proteoglycan
25
DSC
24
SDS
24
glial fibrillary acidic protein
24
type I collagen
24
asymmetrical
24
rhodopsin
23
IL-6
23
p53
22
AFM
22
thymus
22
CSF
22
CO2
21
Pseudomonas
21
Pol
21
tumor necrosis factor
21
IgA
21
ANOVA
20
VEGF
20
Rec
19
casein
19
parathyroid hormone
19
fibronectin
19
osteogenic
18
superoxide dismutase
18
keratin
18
PEO
18
MMP-9
18
ERG
17
PBS
17
osteocalcin
17
glycoprotein
17
polypeptide
17
renin
17
BMD
16
COL4A3
16
Mal
16
MMP-2
16
fused
16
smooth muscle actin
16
Hip
16
CA1
16
amylase
15
COL4A4
15
corneal dystrophy
15
membrane protein
15
Poly
15
cardiac muscle
15
amyloid precursor protein
15
SMA
15
myosin
14
glucan
14
vimentin
14
strabismus
14
angiotensin II
14
serum albumin
14
osteosarcoma
13
peroxidase
13
Bot
13
estrogen receptor
13
collagenase
13
apolipoprotein E
13
PCB
13
EPA
13
Ki-67
13
Rho
12
Men
12
cage
12
lacrimal
12
ferritin
12
IPL
12
chronic renal failure
12
CA3
12
Bcl-2
12
lysozyme
12
membrane-bound
12
hairless
11
catenin
11
growth hormone
11
lipopolysaccharide
11
CD4
11
tyrosine hydroxylase
11
catalase
11
lymphoid
11
interleukin-6
10
APOE
10
IL-10
10
GBM
10
reserved
10
phosphodiesterase
10
desmin
10
MMP-1
10
CD8
10
RPE
10
insulin-like growth factor
10
Gen
10
brush border
10
metalloproteinase
10
calbindin
9
thrombin
9
E11
9
IFN
9
glucocorticoid receptor
9
glucosamine
9
neurofibromatosis
9
PLA
9
creatine kinase
9
reductase
9
TGF-beta
9
MMP-3
9
SOD
8
PDGF
8
synuclein
8
extracellular signal-regulated kinase
8
antioxidant enzyme
8
C18
8
C-reactive protein
8
long chain
8
IgE
8
involucrin
8
IL-4
8
fibrinogen
8
calcium channel
8
GSH
8
calcitonin
8
E14
8
more...
Disease
cornea
324
Alzheimer's disease
224
myocardial infarction
216
keratoconus
196
glaucoma
169
tumor
166
ischemia
153
osteoporosis
151
cognitive impairment
146
heart failure
133
diabetes
131
dementia
125
cancer
125
hypertension
122
intraocular pressure
110
myopia
105
depression
104
dysplasia
102
osteoarthritis
96
cataract
94
plaque
93
schizophrenia
90
Parkinson's disease
80
astigmatism
79
neuropathy
78
blindness
78
atherosclerosis
77
stroke
76
cardiomyopathy
75
multiple sclerosis
71
hydrocephalus
67
SEM
67
acute myocardial infarction
65
retinopathy
65
Alport syndrome
64
sclera
61
dilated cardiomyopathy
61
brain atrophy
59
renal disease
56
hypertrophic cardiomyopathy
52
myocardial ischemia
52
proteinuria
52
TEM
51
TEM
51
congestive heart failure
50
cold
49
keratitis
49
ventricular hypertrophy
48
HIV
48
diabetic retinopathy
47
macular degeneration
47
optic neuritis
46
epilepsy
46
ventricular dilatation
45
autism
43
West
42
psoriasis
41
prolapse
40
arthritis
40
psychosis
40
rheumatoid arthritis
40
coronary artery disease
39
retinitis pigmentosa
39
retinal detachment
38
coronary occlusion
35
uterus
35
developmental delay
34
Anterior
34
conjunctiva
34
ash
33
sarcoidosis
31
Best
31
renal failure
30
deafness
29
cardiovascular disease
29
refractive error
29
heart disease
29
obesity
28
pruritus
28
mitral regurgitation
28
AGA
27
optic atrophy
27
scotoma
27
breast cancer
27
amyotrophic lateral sclerosis
27
fits
26
hyperkeratosis
25
myocarditis
25
SDS
25
type 2 diabetes
24
mental retardation
24
dehydration
24
bone disease
24
keratopathy
24
malnutrition
23
mental retardation
23
glomerulonephritis
23
corneal ulcer
23
Retina
22
dysphagia
22
major depressive disorder
22
Retina
22
hydronephrosis
22
megalocornea
22
squamous cell carcinoma
21
systemic lupus erythematosus
21
spastic paraplegia
20
Huntington's disease
20
hyperparathyroidism
20
AIDS
20
melanoma
20
Cornea
19
macular edema
19
aphasia
19
Cornea
19
scleroderma
19
scleritis
19
strabismus
19
carcinoma
19
immunodeficiency
19
glomerulosclerosis
19
hyperglycemia
19
telangiectasia
18
vascular disease
18
epiphysis
18
skin disease
18
parakeratosis
18
scoliosis
17
varices
17
chronic renal failure
17
BMD
17
hernia
17
PSS
17
muscular atrophy
17
corneal degeneration
17
asthma
17
type 1 diabetes
16
vasculitis
16
nystagmus
16
pathological fracture
16
bipolar disorder
16
Autism
16
IgA nephropathy
16
pulmonary hypertension
16
peripheral neuropathy
16
atrioventricular block
16
tumor growth
16
lung disease
16
conjunctivitis
15
virus infection
15
connective tissue disease
15
uveitis
15
dermatitis
15
corneal dystrophy
15
Down syndrome
14
Evans
14
nephrotic syndrome
14
rare disease
14
abdominal aortic aneurysm
14
hypogonadism
14
more...
Symptom
thinning
11252
pain
170
collapse
79
weakness
71
seizures
49
ataxia
41
anesthesia
41
headache
32
dry eye
32
hypotonia
27
discomfort
22
fatigue
22
discomfort
21
spasticity
21
diarrhea
21
erythema
20
chest pain
19
tremor
18
pallor
18
dyspnea
17
asynergy
16
abdominal pain
15
blurred vision
15
functional recovery
15
agitation
15
starvation
14
paraparesis
13
nausea
13
cerebellar ataxia
12
photophobia
12
paresis
12
vomiting
12
angina
11
acidity
11
regurgitation
11
cough
10
syncope
10
distraction
9
respiratory distress
9
spasm
9
constipation
9
knee pain
9
hyperoxia
9
hemiplegia
8
dizziness
8
polyuria
8
dysarthria
7
dystonia
7
dysuria
7
apathy
7
vertigo
6
skin damage
6
shoulder pain
6
arthralgia
6
sleepiness
5
memory loss
5
back pain
5
fasciculation
5
flank pain
5
hypothermia
5
epigastric pain
5
dry skin
5
low back pain
4
abiotrophy
4
nausea and vomiting
4
numbness
4
rhinorrhea
4
tinnitus
4
heel pain
4
exertional dyspnea
4
stigma
4
bone pain
4
eye pain
4
hemoptysis
4
hepatomegaly
4
muscle stiffness
4
visual hallucination
4
hip pain
3
nasal discharge
3
hypercapnia
3
exhaustion
3
blepharospasm
3
Visual symptoms
3
pachyonychia
3
overweight
3
polydipsia
3
hot flushes
3
urinary frequency
3
analgesia
3
ataxic gait
3
Decreased activity
3
clubbing
3
intention tremor
3
anorexia
3
anosmia
3
asthenia
3
bradykinesia
3
koilonychia
3
Prodrome
3
physical appearance
3
Wind
3
cyanosis
3
myalgia
3
atypical chest pain
3
neck pain
3
tachypnea
3
onychomadesis
2
neurological disability
2
masculinization
2
tense
2
Burning
2
shortness of breath
2
leg pain
2
tingling
2
Depressive symptoms
2
incoordination
2
emaciation
2
myoclonus
2
abnormal gait
2
acute abdomen
2
joint stiffness
2
ophthalmoplegia
2
limb pain
2
irregular bleeding
2
paresthesia
2
skin irritation
2
Dellen
2
pelvic pain
2
loss of balance
2
generalized erythema
2
sciatica
2
twitching
2
eds
2
ENT
2
Ill
2
hepatosplenomegaly
2
hunger
1
partial seizure
1
Skin thickening
1
Fluctuation
1
Catch
1
Bitot's spots
1
leg cramps
1
Scratch
1
photopsia
1
lethargy
1
tonic seizure
1
dysosmia
1
athetosis
1
bitter taste
1
Welt
1
dysesthesia
1
metamorphopsia
1
meningism
1
lassitude
1
clonus
1
thigh pain
1
HSA
1
cachexia
1
stomach cramps
1
more...
Drug
Dermatol
197
Cardiovasc
95
Leaf
27
lysine
26
CSF
23
nitroglycerin
21
Fluorescein
17
vitamin E
15
ascorbate
15
MAP
14
Fluorescein
14
Gel
13
PCB
13
Monit
13
Frontal
12
lactose
9
HCH
8
Biopolymers
8
Depo-Provera
8
PTH
7
ROS
7
Xanthan gum
7
NADH
7
Gelatin
7
SiO2
7
CTX
6
balanced salt solution
6
EE2
6
ABC
5
Triclosan
5
Clobetasol propionate
5
PPA
5
Ringer's solution
5
IL-2
5
ROC
5
Spectrum
5
TiO2
5
Norplant
4
Gramicidin
4
DMSA
4
Retinoic acid
4
Herceptin
4
Spectrum
4
citric acid
4
Camp
4
Prednisolone farnesylate
4
Guar gum
4
Dial
4
Meditec
3
Azithromycin
3
Indomethacin
3
Glutathione
3
Ethanol
3
Sodium alginate
3
TAC
3
CTX
3
EPA
3
Vitamin A
3
Phosphatidylserine
3
CaCl2
3
caffeine
3
CTX
3
Zoladex
3
CaCl2
3
Prednisolone
3
CaCl2
3
Bevacizumab
3
ETA
3
Mutagen
3
Carbopol 940
3
Norplant
3
Becotide
2
TAT
2
niacin
2
Tocopherol
2
Crixivan
2
Optison
2
Methylprednisolone
2
Galactose
2
Prednicarbate
2
Gelfoam
2
AZT
2
Dithranol
2
Asthma
2
Dakar
2
TES
2
Permalens
2
DHT
2
Wine
2
ZnO
2
Glycerol
2
Dihydrotestosterone
2
Ouabain
2
Infliximab
2
G-CSF
2
Clobetasone butyrate
2
DHT
2
Isotretinoin
2
AZT
2
Riboflavin
2
IL-1ra
2
Histamine
2
Poloxamer 188
2
Gastro
2
Levonorgestrel
2
Infliximab
2
Fluticasone propionate
2
Adriamycin
2
Silica
2
Carbopol 934
2
DNase I
2
Atropine
2
Crixivan
2
Finasteride
2
THA
2
Nitric Oxide
2
ENT
2
Zoladex
2
Anakinra
2
CDP
2
Zmax
2
Crixivan
2
Flixotide
1
Codeine
1
Viracept
1
Brij 96
1
Clodronate
1
DM1
1
Nasonex
1
ADM
1
Photofrin II
1
Vitamin E
1
DPA
1
Ipriflavone
1
Vitamin K
1
Lipiodol
1
Polysorbate 20
1
CFX
1
Pemetrexed
1
Theophylline
1
Donepezil
1
Lidofilcon A
1
Latanoprost
1
Psyllium husk
1
Tween 60
1
Indocyanine green
1
Pregabalin
1
Monensin
1
Femara
1
Irinotecan
1
RFP
1
Zein
1
Cortisporin
1
CEC
1
Bisacodyl
1
Indinavir
1
Ethane
1
Photofrin
1
Iohexol
1
AraC
1
more...
Enzyme
ACS
143
alkaline phosphatase
34
ERK
30
ATPase
26
collagenase
25
caspase-3
25
superoxide dismutase
24
mitogen-activated protein kinase
24
peroxidase
17
renin
17
protein kinase C
16
ACE
15
catalase
14
lysozyme
12
protein kinase
11
creatine kinase
10
focal adhesion kinase
10
tyrosine hydroxylase
10
phosphodiesterase
10
MMP-3
10
acetylcholinesterase
10
thrombin
8
hyaluronidase
8
alanine aminotransferase
8
acid phosphatase
8
elastase
8
trypsin
7
cellulase
7
transglutaminase
7
hyaluronidase
7
tyrosinase
7
lysyl oxidase
6
NO synthase
6
aspartate aminotransferase
6
cholinesterase
6
AMPK
5
reverse transcriptase
5
glutathione peroxidase
5
glutamine synthetase
5
proteasome
5
MMP
5
plasmin
5
matrix metalloproteinase 9
5
choline acetyltransferase
5
lactate dehydrogenase
5
CDR
4
urokinase-type plasminogen activator
4
carbonic anhydrase
4
lipase
4
matrix metalloproteinase 2
4
cytochrome oxidase
4
NQO1
4
pepsin
4
complex I
4
invertase
4
PARP
4
transcriptase
3
RNA polymerase
3
NOS
3
caspase-8
3
laccase
3
AMPK
3
tryptase
3
AMP-activated protein kinase
3
MAP
3
pyruvate dehydrogenase
3
calcineurin
3
hexosaminidase
3
glucocerebrosidase
3
prostaglandin synthetase
3
beta-galactosidase
3
adenylate cyclase
3
TdT
3
pyruvate dehydrogenase
3
pyruvate dehydrogenase
3
kallikrein
2
glutaminase
2
tissue kallikrein
2
angiotensin-converting enzyme 2
2
aconitase
2
glutathione S-transferase
2
chymase
2
glyceraldehyde-3-phosphate dehydrogenase
2
caspase-6
2
caspase-9
2
chitinase
2
caspase-6
2
interstitial collagenase
2
MDP
2
phosphatidylinositol 3-kinase
2
chymotrypsin
2
TPP
2
SOI
2
glucose oxidase
2
tissue plasminogen activator
2
phosphofructokinase
2
APC
2
MIP
2
phosphoenolpyruvate carboxykinase
2
pyruvate kinase
2
Mg2+-ATPase
2
leucine aminopeptidase
2
phosphoinositide 3-kinase
2
prolyl hydroxylase
2
granzyme B
2
phosphoenolpyruvate carboxykinase
2
urease
2
phospholipase A2
2
phosphoenolpyruvate carboxykinase
2
glyceraldehyde-3-phosphate dehydrogenase
2
phospholipase C
2
CD10
2
urease
2
TAT
2
NADPH oxidase
2
gamma-glutamyl transpeptidase
2
NADPH-diaphorase
2
sucrase
2
glyceraldehyde-3-phosphate dehydrogenase
2
NADPH oxidase
2
SPT
2
alcohol dehydrogenase
2
glyceraldehyde-3-phosphate dehydrogenase
2
glyceraldehyde-3-phosphate dehydrogenase
2
neuraminidase
2
cathepsin B
2
pectinase
2
sucrase-isomaltase
1
glutamate dehydrogenase
1
GAS
1
bromelain
1
UDP-glucose dehydrogenase
1
TSA
1
legumain
1
lactase
1
monoamine oxidase
1
cathepsin K
1
neutrophil elastase
1
ADH
1
PAL
1
BIS
1
CaMKII
1
DNA polymerase
1
myosin light chain kinase
1
PAT
1
amylomaltase
1
STR
1
PAL
1
BMA
1
polo-like kinase 1
1
UDP-glucuronosyltransferase
1
LDT
1
cdc2
1
CPT
1
DNA methyltransferase
1
CPT
1
lipoxygenase
1
GSK
1
PvdQ
1
TPP
1
more...
Compound
water
923
Dec
681
Clin
361
sodium
204
calcium
199
oxygen
189
DNA
172
Cardiol
172
ACS
143
ACS
143
glucose
136
hydrogen
104
phosphate
103
Retinal
100
salt
98
nitrogen
79
PEG
77
galactose
70
silicon
70
hyaluronic acid
66
sulfate
62
iron
60
ethanol
59
His
55
Cereb
53
TEM
53
PEG
52
DDE
51
phosphorus
48
urea
44
acetate
43
glutamate
39
potassium
39
silver
39
bromide
38
CO2
38
Collagen
38
glycerol
36
DDT
36
copper
33
creatinine
32
arginine
31
lysine
31
vitamin D
30
xylose
30
titanium
30
ATP
29
nitric oxide
26
dUTP
25
TNF
25
SDS
24
ammonium
23
zinc
22
cysteine
22
carbonate
21
iodine
19
acrylamide
19
Pluronic
19
hydroxide
19
retinoic acid
18
aluminum
18
leucine
18
nitrate
18
alanine
17
serine
17
BMD
16
aldehyde
16
mercury
16
nickel
16
NH2
15
POPC
15
aldehyde
14
sodium chloride
14
Starch
14
A 3
14
acetic acid
13
NIDA
13
DMSO
13
HCl
13
DMPC
13
Cellulose
13
tyrosine
13
Carbon
13
MAP
13
A 42
12
H2S
12
fluorine
12
hexadecane
12
DPPH
12
Neuronal
12
Optimal
11
Phe
11
DTPA
11
proline
11
EDTA
11
vinyl
11
EDTA
11
propylene glycol
10
acrylic acid
10
GSH
10
GSH
10
glutamic acid
10
Hematoxylin
10
propylene glycol
10
PAS
10
DPPC
9
PGE2
9
Phytol
9
hexane
9
molybdenum
9
DDD
9
Phytol
9
aldosterone
9
methionine
9
Tween 80
9
homocysteine
9
methanol
9
Adrenal
9
barium
9
DPPC
9
pyrene
8
retinol
8
manganese
8
sulfuric acid
8
PLA
8
methane
8
tryptophan
8
ASA
8
decane
8
tryptophan
8
cAMP
8
Estrogen
8
Alginate
8
formaldehyde
8
tryptophan
8
tryptophan
8
Isoproterenol
8
Salt
7
STZ
7
cGMP
7
NADH
7
Etretinate
7
ABA
7
Xanthan
7
SiO2
7
toluene
7
DSM
7
Hearts
7
Dexamethasone
7
Asp
7
MgO
7
Hearts
7
boron
7
cadmium
7
MIC
6
PPA
6
ADP
6
ammonia
6
Adriamycin
6
ABA
6
more...