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Query: UMLS:C0851184 (thinning)
 11,252 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

As part of an examination of 180 patients with optic disc drusen fundus photographs of 159 cases were evaluated. Twenty-one patients had no fundus photographs, and 12 cases had only autofluorescence pictures, positive colour transparencies or fluorescein angiograms. Peripapillary retinal nerve fibre layer (RNFL) was examined in 147 patients from black-and-white stereo-photographs of the optic disc (116) or from special RNFL pictures (4) or from both (27). Fifty-three of 147 patients had been photographed two or more times during the years from 1967 to 1981. The regional grading of the RNFL was performed separately from 6 sectors around the disc from 386 series of photographs, and the findings were later compared with the patients' visual fields. The eyes with buried drusen usually showed normal RNFL and normal fields, but the visible drusen were often associated with thinning or slits or atrophy of the peripapillary nerve fibre bundles and with visual field defects.
Acta Ophthalmol (Copenh) 1982 Dec
PMID:Optic disc drusen--a photographic study. II. Retinal nerve fibre layer photography. 717 Sep 31

The significance and usefulness of two-dimensional echocardiography (2DE) in the evaluation of superacute phase of myocardial infarction were studied in 13 dogs with coronary occlusion, and 2DE findings were compared with the hemodynamic indices. Myocardial infarction was produced by the occlusion of anterior descending branch of the left coronary artery in 13 anesthetized adult mongrel dogs. In 6 dogs, the end-diastolic area and percent fractional shortening (%FS) in each short-axis view of the left ventricle at the level of the mitral valve, chordae tendineae, papillary muscles, low papillary muscles and apex were measured during 60 minutes, and end-diastolic wall thickness of infarct area situated in the transitional zone between the septum and the anterior wall were compared with that of non-infarct area immediately and subsequent 60 minutes after occlusion. Positive dP/dt/P, time constant T and cardiac output were measured simultaneously with an echocardiographic study. Severe enlargement and expansion of the left ventricular cavity (ballooning) and a decrease of %FS and thinning of the left ventricular wall perfused by the occluded artery occurred immediately after occlusion and persisted during subsequent 60 minutes. Time constant T was significantly prolonged, while positive dP/dt/P and cardiac output were decreased immediately and continued up to 60 minutes after occlusion. 2DE findings corresponded well with the changes of cardiac function and hemodynamics determined simultaneously. We concluded that the detection of the left ventricular ballooning is important in the diagnosis of superacute phase of myocardial infarction in dogs.
J Cardiogr 1982 Dec
PMID:[Echocardiography in superacute phase of myocardial infarction: an experimental study]. 718 11

Long-term hydrosalpinges were mechanically induced in rabbits by ligation of the fimbriated end of the oviduct. The structure and function of these model hydrosalpinges were studied 28 to 52 weeks following ligation. This procedure caused a nonpurulent, clear serous fluid to accumulate within the lumen of the ampulla, which resulted in dilatation of the ampulla and thinning of the tubal wall. The intraluminal mucosal folds were attenuated in the expanded regions; however, normal ciliation was predominant throughout the endosalpinx. Two rabbits, one with a single distal tubal ligation and the other with double ampullary ligation, showed abnormal epithelium with distinct patches of flattened polygon-shaped, nonciliated cells. In vivo and in vitro observations of luminal transport of surrogate ova in cumulus showed that ciliary transport was not affected by the long-term gross distension of the ampullae. The authors conclude that long-term tubal dilatation by itself does not alter tubal morphology sufficiently to impair ovum transport function in the oviductal ampulla.
Fertil Steril 1981 Dec
PMID:Mechanically-induced hydrosalpinx: long-term oviductal dilatation does not impair ciliary transport function. 730 26

Renal disease, although not a cardinal feature of the Laurence-Moon-Biedl-Bardet syndrome (LMBBS), occurs in more than 70% of patients and is an important cause of morbidity and mortality. Renal ultrastructural changes have not been well delineated. We have studied glomeruli from three patients with LMBBS and have found similar ultrastructural changes in glomerular basement membrane (GBM). Two patients had decreased renal function, hypertension, and markedly abnormal intravenous urograms with reduced concentration of dye and abnormal pelvicalyceal systems; one patient had normal renal function and minimal distortion of the pelvicalyceal system of one kidney. Ligh microscopy revealed varying degrees of increase in mesangial cellularity and matrix. These changes involved almost all glomeruli and were segmental. The abnormalities ranged from mild mesangial cell proliferation to complete sclerosis of the glomerular tuft. Ultrastructural study revealed marked alterations of the glomerular basement membrane: effacement of the trilaminar architecture, segmental and irregular thickening alternating with thinning and rarefaction, accumulation of granular and fibrillary material within the inner third of the GBM. These ultrastructural changes may be the earliest and primary glomerular abnormality seen in LMBBS because they were seen in a patient who had minimal changes on light microscopy.
Clin Nephrol 1981 Dec
PMID:Ultrastructural changes in the glomerular basement membrane of patients with Laurence-Moon-Biedl-Bardet syndrome. 731 62

This paper presents a brief historical review and details of one case of this condition. Terrien's marginal corneal degeneration involves a relatively painless degeneration of the superior corneal stroma, with the most prominent clinical finding being the marked irregular astigmatism which accompanies the corneal thinning.
Am J Optom Physiol Opt 1981 Dec
PMID:Terrien's marginal corneal degeneration: a case report. 732 3

Description of a patient with keratoconus posticus acutus. The typical changes including thinning, were seen clinically on the posterior central surface of the left cornea with conical protrusion of the internal curvature. The right eye showed the classic signs of the acute phase.
Klin Monbl Augenheilkd 1981 Dec
PMID:[A case of Keratokonus posticus acutus (author's transl)]. 734 18

In 15 open-chest, anesthetized dogs, regional systolic wall thickening (% delta WT) was measured with sonomicrometry and regional blood flow was determined with tracer microspheres (7-10 micron) before and after various degrees of coronary artery narrowing were created with a hydraulic occluder. The stenoses were categorized into four groups by the effect on % delta WT, and the corresponding myocardial blood flow (MBF) was determined in four layers across the ventricular wall (layer 1: subendocardium; layer 4: subepicardium). In group 1, % delta WT decreased 44 +/- 10% and only layer 1 MBF was significantly reduced (-28%); in group 2, % delta WT decreased 77 +/- 8% and MBF was reduced in both layers 1 and 2 (-52% and -36%, respectively); in group 3, % delta WT decreased 104 +/- 3% and MBF was reduced in the three inner layers (layer 1: -65%; layer 2: -58%; layer 3: -34%); in group 4, % delta WT decreased 145 +/- 9% (systolic wall thinning) and transmural reduction of MBF was found (layer 1: -74%; layer 2: -68%; layer 3: -55%; layer 4: -29%). We conclude that (1) up to 75% reduction in systolic wall thickening may occur when perfusion to only the inner one-half of the myocardium is decreased; (2) akinetic wall motion may be observed when perfusion remains normal in the subepicardial one-fourth of the wall; and (3) dyskinesia (wall thinning) occurs when blood flow is reduced transmurally.
Circulation 1980 Dec
PMID:Significance of regional wall thickening abnormalities relative to transmural myocardial perfusion in anesthetized dogs. 743 62

A subjective retrospective analysis of 250 patients was done to better understand a serious long-term complication of inflatable implants. A series of 397 breasts with inflatable prostheses exhibited 32% thinning of the breast tissue. Fifty-six percent of the thinning was found in the first 2 years, and 74% by 3 years. Of those breasts that thinned, 31.5% exhibited the streaking phenomenon. Breasts were divided into categories of bilateral Decadron addition, right-sided addition, and no addition. All groups showed roughly 30% thinning with equal right-sided and left-sided distribution. No treatment is needed for mild thinning (41% of this series), but a change to a gel prosthesis is advocated for more severe cases. Breast thinning following inflatable implants is thought to be related to pressure atrophy, not to the addition of steroids. Generalized tissue malacia has not been seen with the use of gel prostheses. With longer follow-up a higher rate of thinning is anticipated. From this study it is believed the inflatable implant is not the prosthesis of choice, and its use has been discontinued by the author.
Ann Plast Surg 1980 Dec
PMID:Breast thinning and streaking following the use of inflatable implants--a subjective clinical study. 746 23

On the basis of 56 cases of secondary rhinoplasty following an initial open rhinoplasty, I conclude that secondary surgery is safe and effective. Either an open or closed approach can be used in most cases with little risk of skin necrosis or poor scar formation. The decision as to which approach to use depends on numerous factors. In general, a closed technique is favored when augmentation is the solution, while an open technique is favored when structural correction is required. Reopening the nose was done consistently without problems but was avoided in two patients because of severe thinning following previous defatting. However, certain "stigmata" were seen following open primary rhinoplasty and should be avoided: (1) a depressed, visible scar, (2) destruction of the soft-tissue facets and nostril apices, (3) columella deformities with associated nostril asymmetry, and (4) excessive tip or supratip defatting.
Plast Reconstr Surg 1995 Dec
PMID:Secondary rhinoplasty following open rhinoplasty. 748 Feb 73

The Moore monopolar hemiarthroplasty is useful in the management of patients with femoral neck fractures, but long-term results may be associated with acetabular cartilage degeneration and hip pain. The authors report a case of long-term function of a Moore hemiarthroplasty. A 61-year-old woman sustained a fracture of the neck of the femur, which was treated initially with pinning. One year later, because the operation had failed, the patient underwent a Moore hemiarthroplasty. The prosthesis functioned well for 32 years, when she experienced increasing pain in the groin and a decreasing range of hip motion. Radiologic examination showed thinning of the acetabular cartilage so a total hip arthroplasty was performed. This case demonstrates that a unipolar arthroplasty is capable of long-term function, and with current improvements in stem fixation improved longevity can be expected.
Can J Surg 1995 Dec
PMID:Moore hemiarthroplasty functioning for 33 years: a case report. 749 71


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