Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0851184 (thinning)
 11,252 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two hundred and twenty-one representative samples of chicken eggs of native and commercial strains of Gallus domesticus were collected during January 1975 to August 1977 throughout the Tehran area and the Northern province of Mazandarane. The samples were analyzed for chlorinated pesticide residues by gas-liquid chromatography. The insecticides [1,1,1-Trichloro-2,2-bis (P-Chlorophenyl)ethanel] (DDT), [1,1-Dichloro-2,2-bis (P-Chlorophenyl) ethane] (TDE), [1,1-Dichloro-2,2-bis (P-Chlorophenyl)ethylene] (DDE), isomers of benzene hexachloride (BHC), Aldrin/Dieldrin, Heptachlor/Heptachlor epoxide, Dieldrin, and endrin were detected in varying concentration in the eggs. The eggs of native bred chickens, mainly as a result of their food sources, showed greater concentration of all pesticides except BHC isomers than those of commercial types. Though concentration of DDT compounds in 22% of native bred and 5% of commercial eggs exceeded WHO tolerance limit, the mean concentrations of pesticides residues were not exceeding these limits. There was no correlation between concentrations of pesticides and egg shell thinning.
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PMID:Chlorinated pesticide residues in chicken egg. 9 64

The northern gannets (Sula bassanus) nesting on Bonaventure Island, Quebec, were studied from 1968 to 1984 in order to measure environmental contaminant levels and their relationship to productivity. Fresh eggs in 1969 contained a mean DDE level of 18.5 mg kg(-1) and had shells which were 17% thinner than pre-1947 samples. Unhatched eggs in 1969 had no outer calcified layer, a mean thickness 20% less than the pre-1947 mean, and mean DDE concentration of 30.6 mg kg(-1). Significantly higher levels of eight contaminants were measured in unhatched than in fresh eggs collected in 1969. DDE and shell thinning were also intercorrelated with nine other contaminants; these data strongly implicate toxic chemicals, particularly DDE, as the main cause for the low breeding success of Bonaventure gannets from 1966 to 1974. Extensive use of DDT to control forest insects around the Gulf of St Lawrence ceased in 1969. Use of DDT, dieldrin and PCBs was restricted in North America during the early 1970s. Residues of DDT, DDD, DDE, PCBs, dieldrin, HCB and chlordane-related compounds in gannet eggs decreased significantly during this study. Heptachlor epoxide remained constant while alpha-HCH appeared to increase. Estimated half-lives ranged from 3.1 years for DDD to 35.4 years for oxychlordane. The breeding success and population of the colony have coincidentally increased.
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PMID:Organochlorines and eggshell thinning in northern gannets (Sula bassanus) from Eastern Canada, 1968-1984. 1509 9