Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0851184 (thinning)
 11,252 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Dosages, costs, side effects, and drug interactions are discussed for each approved protease inhibitor: Invirase (Saquinavir, hard-gel capsules), Crixivan (Indinavir), Norvir (Ritonavir), Viracept (Nelfinavir), and Fortovase (Saquinavir, soft-gel capsules). Information on Agenerase (amprenavir), an experimental drug not yet approved by the FDA for commercial use, is also given. Protease inhibitors may require strict dosing schedules and food restrictions; most are associated with lipodystrophy (thinning of the arms, legs and face with fat accumulation in the breasts, stomach, and sometimes the upper back). The drug's manufacturer, a doctor, and an activist offer comments. Contact information is provided.
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PMID:What they say about protease inhibitors. 1136 22