Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0851184 (thinning)
 11,252 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Summaries of seven recently published studies on the association between contraceptive method and sexually transmitted diseases (STDs) have confirmed the effectiveness of latex condom use, but produced inconclusive findings in terms of other methods. It has been suggested that physiological changes induced by the progesterone in oral contraceptives (OCs) (e.g., cervical ectropion and a higher incidence of chlamydia) and injectables (e.g., irregular menstrual bleeding and thinning of the vaginal lining) may increase susceptibility to HIV. On the other hand, a Kenyan study found no significant trend in HIV risk with duration of use of OCs, injectables, or IUDs. In a study from Rwanda, HIV prevalence was significantly elevated among injectable and OC users; however, this association disappeared when type of sexual relationship (e.g., nonmonogamous) and marital status were controlled. Couples who want simultaneous protection against pregnancy and STDs may need to use two contraceptive methods.
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PMID:Progesterone and STDs: selected studies. 1229 89