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Query: UMLS:C0851184 (thinning)
 11,252 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A period of acute diarrhoea in infants is often associated with anorexia and weight loss. Catch-up growth is, therefore, necessary and this depends very much on the type of food, in terms of nutrient density, protein quality and digestibility, given to the child. Fermented (F) and non-fermented (NF) maize-soybean porridges of increased nutrient density were formulated and compared with traditionally fermented maize-only porridge (P) for acceptability using mothers in peri-urban Ghana as well as urban Nigeria as subjects. Subsequently, infants hospitalised in paediatric wards for acute diarrhoea, from the same communities in both countries, were assigned randomly to one or other of the three porridges. Infant subjects in all cases fell within the ages of 6-15 months. Complementary to regular breast-feeding, infants could consume as much porridge as they wanted and their total daily consumption was interpreted as an indication of acceptance. Although mothers in both the environments of Ghana and Nigeria rated P as more acceptable than F and NF, no significant difference was recorded in the quantitative intake by infants of the three formula groups. By adding enzyme-rich cereal malt flour (at the 1-5% level by weight) as a viscosity-thinning agent to F and NF porridges, it was possible to feed these porridges to infants at total solids concentration levels of 20-25% (wet basis) which is approximately double the solid matter content of the P porridge. Consequently, the daily nutrient intake by infants consuming F and NF porridges was considerably higher compared to the P porridge group. It is concluded that the concept of high nutrient density weaning foods is a feasible vehicle for an improvement of nutrient supply to infants.
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PMID:Feeding of lactic acid-fermented high nutrient density weaning formula in paediatric settings in Ghana and Nigeria: acceptance by mother and infant and performance during recovery from acute diarrhoea. 857 62

Renal TB is difficult to diagnose, because many patients present themselves with lower urinary symptoms which are typical of bacterial cystitis. We report a case of a young woman with renal TB and ESRD. She was admitted with complaints of adynamia, anorexia, fever, weight loss, dysuria and generalized edema for 10 months. At physical examination she was febrile (39 degrees C), and her abdomen had increased volume and was painful at palpation. Laboratorial tests showed serum urea = 220 mg/dL, creatinine = 6.6 mg/dL, hemoglobin = 7.9 g/dL, hematocrit = 24.3%, leukocytes = 33,600/mm(3) and platelets = 664,000/mm(3). Urinalysis showed an acid urine (pH = 5.0), leukocyturia (2+/4+) and mild proteinuria (1+/4+). She was also oliguric (urinary volume < 400 mL/day). Abdominal echography showed thick and contracted bladder walls and heterogeneous liquid collection in the left pelvic region. Two laparotomies were performed, in which abscess in pelvic region was found. Anti-peritoneal tuberculosis treatment with rifampin, isoniazid and pyrazinamide was started. During the follow-up, the urine culture was found to be positive for M. tuberculosis. Six months later the patient had complaints of abdominal pain and dysuria. New laboratorial tests showed serum urea = 187 mg/dL, creatinine = 8.0 mg/dL, potassium = 6.5 mEq/L. Hemodialysis was then started. The CT scan showed signs of chronic nephropathy, dilated calyces and thinning of renal cortex in both kidneys and severe dilation of ureter. The patient developed neurologic symptoms, suggesting tuberculous meningoencephalitis, and died despite of support measures adopted. The patient had ESRD due to secondary uropathy to prolonged tuberculosis of urinary tract that was caused by delayed clinical and laboratorial diagnosis, and probably also due to inadequate antituberculous drugs administration.
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PMID:End-stage renal disease due to delayed diagnosis of renal tuberculosis: a fatal case report. 1762 50

A 74-year-old woman was admitted to our emergency room complaining of general weakness and anorexia that started 20 days earlier. She denied other underlying diseases that might have provoked chronic renal disease. Her serum creatinine was 12.35 mg/dL. A pelvic examination and computed tomography revealed severe bilateral hydroureteronephrosis with marked cortical thinning induced by total uterine prolapse. She was started on emergency hemodialysis due to her uremic symptoms and severe metabolic acidosis. Despite Foley catheter insertion and manual reduction of uterus for 1 month, renal function was not recovered. The department of gynecology was strongly opposed to performing a procedure to reverse the hydroureteronephrosis due to the irreversibility of her renal function. She is undergoing chronic maintenance hemodialysis. This is a case report of rare end-stage renal disease (ESRD) caused by obstructive uropathy due to pelvic organ prolapse (POP). We should consider POP as a cause of ESRD.
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PMID:Obstructive uropathy by total uterine prolapse leading to end-stage renal disease. 2255 23