Gene/Protein
Disease
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Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
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Drug
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Target Concepts:
Gene/Protein
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Query: UMLS:C0851184 (
thinning
)
11,252
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Ventricular aneurysm is usually a complication of acute transmural myocardial infarction. The development of
cardiac aneurysm
represents a process of continued
thinning
and fibrosis of the necrotic tissue of the ventricular wall. Survival allows the development of a solid fibrous scar which of itself does not affect global ventricular function substantially. Hence, ventricular aneurysms can be present for up to 18 years without production of serious symptoms. The cases were reviewed of 45 patients in whom aneurysmectomy and myocardial revascularization were carried out. Surgical mortality was low (6.6 percent, 30 days); survival one year after operation was 76 percent, but at three years had fallen to 47 percent. Cause of late death was dominantly cardiac. In 19 patients post-operative study was done; although graft patency was observed in 98 percent, substantive improvement in ventricular performance was seen in a minority of patients. The outcome in patients with ventricular aneurysm is primarily related to the status of the residual myocardium and to the status of the vessels which supply it. The mechanism of clinical improvement after aneurysmectomy has not been clarified. However, the long-term results appear to be similar to those in patients with extensive myocardial infarction.
...
PMID:Aneurysm of the cardiac ventricle. Its management by medical and surgical intervention. 68 66
Computed tomography is a valuable method for the diagnosis of post-infarction aneurysm of the left ventricle of the heart. It gives additional information concerning the morphological and functional condition of the left ventricle. The suggested method of layer-by-layer scanning improves the diagnostic efficiency of CT during examination of patients with
heart aneurysm
and is noninvasive. Precise individual calculation of the peak concentration of contrast medium, defined by dynamic scanning, optimises the process of gated CT. CT makes it possible to study changes in cavity configuration, left ventricle wall
thinning
, induration and calcification of the myocardium, changes in left ventricle wall mobility, decreased thickening of the myocardium at systole and left ventricle cavity thrombosis--all changes characteristic of left ventricular aneurysm. CT provides important additional information about the condition of the inter-ventricular septum. EDV, ESV and EF data obtained using CT produce important information about the functional state of the left ventricle. Computed tomography can be used as an independent method of left ventricle aneurysm detection, especially in those institutions where more complicated investigation methods are not used and interventional cardiac procedures are not practised. Complex use of computed tomography and left ventriculography in cardiosurgical institutions makes it possible to improve significantly the diagnosis of
cardiac aneurysm
. Calculation of integral data about left ventricle pumping function based on CT and LVG data gives proper evaluation of the indications for operative intervention in left ventricular aneurysm.
...
PMID:Computed tomographic evaluation of morphological and functional condition of left ventricle in heart aneurysm. 369 32
Cardiac aneurysm
occurring in ventricles is usually a complication of acute transmural myocardial infarction. The development of
cardiac aneurysm
represents a process of continued
thinning
and fibrosis of the necrotic tissue of the ventricular wall. Survival of the person without any complication depends on the development of the solid fibrous scar, which seals the aneurysmal cavity.We present an incidental case wherein a person survived with a ventricular aneurysm that sealed itself by natural means due to the development of a thrombus and fibrous tissue offering a natural protection. The person died because of head injury in a road traffic accident in this particular case.
...
PMID:Cardiac aneurysm: a nature's way of correction. 2394 38