Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
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Target Concepts:
Gene/Protein
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Query: UMLS:C0851184 (
thinning
)
11,252
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Morphological specific features of proximal and distal bronchi and bronchioles were studied in secondary
chronic bronchitis
as compared to the primary one basing on the morphometric data. Some specificity was noted in separate forms of secondary bronchitis. Secondary
chronic bronchitis
is characterized by non-uniform pathological changes in bronchial walls. Wall enlargement, infiltration and sclerosis are more pronounced in secondary
chronic bronchitis
as compared to the primary one. The relative volume of glands and muscles is less in secondary
chronic bronchitis
than in the primary one; the Reid index does not differ from the standard in spite of the enlargement of the mucosal inner layer. Atrophic bronchitis is characterized by
thinning
of mucosal inner layer and decrease in the number of glands. Secondary
chronic bronchitis
is characterized by narrowing of bronchioles, in contrast to the primary
chronic bronchitis
where the mean diameter of bronchioles is extended.
...
PMID:[Morphometric picture of chronic bronchitis in bronchiectases--morphologic and morphometric changes in the proximal and distal bronchi and bronchioles]. 357 51
Fourteen male patients with
chronic bronchitis
and hypoxia had a lateral radiograph of the pituitary fossa. Nine of the 14 had definite or probable abnormalities, a significantly higher frequency (p less than or equal to 0.01) than is represented by the two out of 14 age-matched men from a control group with head injuries. The most common change was
thinning
or erosion of the lamina dura. Patients with hypercapnia were no more prone to such abnormalities than were those with normocapnia, a finding that conflicts with a previous paper. We confirm that radiological pituitary fossa changes do occur in
chronic bronchitis
, that they are unrelated to steroid treatment, and that they are probably not solely due to the chronically raised intracranial pressure associated with hypercapnia. Other possible mechanisms are discussed--in particular hypoxia, which might produce changes on account of the increased cerebral blood flow and engorged intracranial blood vessels.
...
PMID:Radiological pituitary fossa changes in chronic bronchitis. 713 92
Using transmission electron microscopy, erythrocyte ultrastructure in norm and pathology was described. Among the morphological phenomena, most common were local and extensive erythrocyte plasmalemmal defects in the form of its loosening,
thinning
, consolidation and thickening, rupture, fragmentation, exfoliation from stroma with the formation of cavities. Plasmalemmal destruction may be accompanied with the formation of micro- and macroexovesicles, some of which lose the connection with the erythrocyte. Morphological signs of erythrocyte stromal disorganization included irregular distribution of hemoglobin granules with the formation of the regions of increased and decreased electron density, loosening of the internal structure up to the formation of cavities, as well as endovesicles, partially containing small or large osmiophilic particles. It was shown that in pathological processes of different genesis (malignant tumors,
chronic bronchitis
, burn trauma, schizophrenia) ultrastructural changes of erythrocytes have typical character.
...
PMID:[Erythrocyte ultrastructure in norm and pathology: morphological phenomena and clinical correlations]. 1584 97