Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0849640 (skin damage)
 1,516 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
STK19 10.6
HOGG1 10.5
SOSTDC1 10.3
PNOC 10.3
PEG8 10.0
histamine receptor H1 9.8
PPP6C 9.7
tripartite motif-containing 24 9.7
Kynurenine aminotransferase 9.6
hairless 9.5
kallikrein 7 9.4
SOBP 8.9
WHS 8.9
CXCL12 protein 8.9
CRTC 8.8
ETFDH 8.8
HCA2 8.8
kallikrein 5 8.7
desmocollin 1 8.7
CRTC3 8.7
NOXO1 8.6
TP53BP1 8.6
KIAA1199 8.6
GST T1 8.6
Superoxide dismutase 1 8.5
Bcl-2-like protein 8.5
AGF 8.5
mpo 8.4
aquaporin-3 8.4
CHMP4B 8.1
SLC24A5 8.0
stratum corneum chymotryptic enzyme 8.0
corneodesmosin 7.9
retinoic acid receptor gamma 7.9
TYRP1 7.9
metalloproteinase 1 7.8
hyaluronan-binding protein 7.8
CDT1 7.8
ChemR23 7.8
KLK6 7.8
EWG 7.7
CEAP 7.7
mPGES-2 7.7
GCLC 7.7
SA-1 7.6
matrix metalloproteinase 1 7.6
endogenous angiogenesis inhibitor 7.6
CSF3 7.6
Kallistatin 7.6
K36 7.5
thrombospondin-4 7.5
HA4 7.5
collagen type I alpha 1 7.5
SHK 7.4
variegate porphyria 7.4
IL-31 7.4
WS1 7.4
MAPK-activated protein kinase 7.4
aquaporin 3 7.3
protoporphyrinogen oxidase 7.3
PIAS3 7.3
transglutaminase 1 7.3
uroporphyrinogen III synthase 7.3
TNF receptor-associated factor 2 7.3
MMP-1 7.3
LHA 7.2
ING1 7.1
thioredoxin interacting protein 7.1
FE65 7.1
Mannan-binding lectin 7.1
BASE 7.1
keratin 16 7.1
IL-34 7.0
involucrin 7.0
CSF2 7.0
HAS1 6.9
HN2 6.9
GCH1 6.9
IL-21R 6.9
filaggrin 6.9
more...
Disease
actinic lesion 13.4
Multiple actinic keratoses 12.8
Dermatillomania 12.4
solar skin damage 11.6
Acyl-CoA dehydrogenase deficiency 11.6
Xeroderma 9.8
phytophotodermatitis 9.6
intertrigo 9.4
Actinic prurigo 9.2
Cutaneous pseudolymphoma 9.2
Erythema ab igne 8.9
arcus senilis 8.9
Actinic cheilitis 8.8
freckles 8.8
Irritant contact dermatitis 8.7
Dermatitis artefacta 8.7
Kaposi's varicelliform eruption 8.6
Diaper dermatitis 8.5
perifolliculitis 8.4
photokeratitis 8.3
photodermatitis 8.3
Post-kala-azar dermal leishmaniasis 8.3
CPAF 8.2
varicose ulcer 8.2
Chronic venous insufficiency 8.2
skin cancer 8.0
EB simplex 8.0
ectoparasitism 8.0
stage I melanoma 7.8
Lumpy skin disease 7.8
Pityriasis rubra pilaris 7.7
physical and emotional abuse 7.7
Hand eczema 7.6
Lentigo maligna 7.6
incomplete paraplegia 7.5
WS1 7.5
Purpura fulminans 7.4
Dystrophic epidermolysis bullosa 7.4
variegate porphyria 7.3
Photosensitized 7.3
venous disease 7.3
acute bacterial endocarditis 7.3
Hepatic necrosis 7.2
ETM 7.2
dermatitis 7.1
Fusarium infection 7.1
melasma 7.1
premature aging 7.1
keratosis 7.0
nonmelanoma skin cancer 6.9
dyschromia 6.8
Selenium deficiency 6.6
Dermal 6.5
decubitus 6.5
skin ulcers 6.5
HRS 6.4
incontinence 6.4
HP2 6.4
Koebner 6.4
xerosis 6.4
SME 6.3
seborrheic keratosis 6.2
localized scleroderma 6.2
HMS 6.2
xanthomatosis 6.2
LDS 6.2
photosensitivity 6.1
CEP 6.1
Chronic GVHD 6.1
rosacea 6.1
Spraying 6.1
skin tumor 6.1
Diabetic foot 6.0
xeroderma pigmentosum 6.0
XPB 6.0
venous insufficiency 6.0
leukoderma 6.0
glossitis 5.9
acrodermatitis enteropathica 5.9
incontinence 5.9
more...
Symptom
skin damage 14.4
Skin thickening 10.0
skin impairment 9.9
penile lesion 8.2
No toxic effect 8.0
scaly skin 7.9
blemishes 7.7
skin irritation 7.5
erythema 7.5
dry skin 7.2
skin irritant 6.8
generalized pain 6.7
belching 5.7
retching 5.3
general problem 4.6
emaciation 4.3
hypoproteinemia 4.2
nasal congestion 4.2
HSA 3.8
physical appearance 3.8
photophobia 3.7
discomfort 3.6
discomfort 3.6
thinning 3.5
twitching 3.4
blurred vision 3.3
stridor 3.2
Wind 3.0
splenomegaly 2.7
arthralgia 2.5
cyanosis 2.5
hepatosplenomegaly 2.3
acute stress 2.2
numbness 2.0
lethargy 1.9
nausea 1.8
pain 1.7
flushing 1.7
myalgia 1.7
hypothermia 1.3
analgesia 1.2
agitation 0.8
sleepiness 0.7
stigma 0.7
anorexia 0.6
collapse 0.6
acidity 0.5
tremor 0.2
weakness 0.1
cough -0.2
fatigue -0.3
anesthesia -0.4
dyspnea -0.4
abdominal pain -0.6
vomiting -0.6
headache -1.4
seizures -1.9
Drug
Eusolex 9.7
Eusolex 9.6
Parsol 9.1
Cortisporin 8.6
Red ginseng 8.5
Sesame oil 8.3
Carbopol 940 7.9
Span 20 7.3
Aloe 7.3
Sunitinib malate 7.2
Clobetasol propionate 7.1
Dexrazoxane 7.0
Peridex 6.9
Cyanoacrylate 6.9
Bexarotene 6.9
Bromelain 6.9
Monarch 6.9
Tranilast 6.7
Verteporfin 6.6
Peridex 6.5
Photofrin II 6.3
Hydrochlorothiazide 5.7
Olive oil 5.7
Diclofenac sodium 5.6
Ramipril 5.6
MEA 5.6
Photofrin 5.5
KGF 5.4
Imiquimod 5.3
Iloprost 5.3
Papain 5.2
Helium 5.1
Rutin 5.0
Vitamin E 5.0
Tocopherol 4.9
Glycyrrhiza 4.9
DMSA 4.8
ROS 4.8
Ranitidine 4.7
vitamin E 4.7
Pravastatin 4.7
niacin 4.5
Monensin 4.5
Prednisone 4.4
ADR 4.4
Diphenhydramine 4.3
Doxycycline 4.3
Retinoic acid 4.2
ascorbate 4.2
TAT 4.1
Fentanyl 4.0
Fraction 4.0
ZnCl2 4.0
ZnCl2 4.0
Honey 4.0
ETA 3.9
BH4 3.8
balanced salt solution 3.8
Heme 3.8
Triclosan 3.7
Dermatol 3.7
Ginseng 3.7
MRC 3.6
Gelatin 3.6
Mutagen 3.4
Indomethacin 3.3
ACT 3.3
Paraffin 3.3
Capsicum 3.2
AZT 3.0
ALA 2.9
TiO2 2.9
Bifidobacterium 2.8
AZT 2.8
Vitamin A 2.8
Ethanol 2.7
citric acid 2.7
Fluorescein 2.5
ZnO 2.2
Adriamycin 2.2
more...
Enzyme
vibriolysin 10.0
porphobilinogenase 9.5
KLK7 7.9
macrophage elastase 7.2
protoporphyrinogen oxidase 7.0
BBE 7.0
CAO 6.9
kynureninase 6.8
neutrophil collagenase 6.8
eEF2 kinase 6.5
interstitial collagenase 6.5
MsrA 6.0
type III procollagen 5.9
mevalonate kinase 5.8
collagenase 5.8
transaldolase 5.7
aminopeptidase A 5.6
MMP-3 5.4
TGT 5.4
DNA ligase 5.3
DNA ligase 5.3
PRE 5.0
DCF 5.0
GTP cyclohydrolase I 5.0
neutral sphingomyelinase 5.0
MMP 4.9
deoxyribonuclease 4.8
tyrosinase 4.8
phenol oxidase 4.6
SPT 4.5
chitin synthase 4.5
delta-aminolevulinic acid dehydratase 4.5
lysin 4.3
TAT 4.1
xanthine oxidase 4.1
glutathione peroxidase 4.1
thioredoxin reductase 4.1
catalase 4.1
tissue kallikrein 4.1
TPP 4.0
NADPH oxidase 4.0
elastase 4.0
tryptase 3.9
heme oxygenase 3.9
NADPH oxidase 3.9
6-phosphogluconate dehydrogenase 3.9
6-phosphogluconate dehydrogenase 3.9
TPP 3.9
hyaluronidase 3.8
mitogen-activated protein kinase 3.8
superoxide dismutase 3.8
Alternating 3.7
ornithine decarboxylase 3.7
glutathione reductase 3.7
lactate dehydrogenase 3.7
dipeptidyl peptidase IV 3.6
AOR 3.6
cathepsin G 3.5
cathepsin K 3.5
caspase-3 3.5
TdT 3.5
thermolysin 3.5
PARP 3.4
cathepsin L 3.4
hyaluronidase 3.3
PDK1 3.2
caspase-8 3.2
matrix metalloproteinase 2 3.2
creatine kinase 3.2
pectinase 3.1
MAP 3.1
caspase-9 3.1
peroxiredoxin 3.0
kallikrein 2.8
thyroid peroxidase 2.8
GSK 2.6
aldolase 2.6
hexosaminidase 2.6
phosphofructokinase 2.4
cathepsin D 2.3
more...
Compound
Geniposidic acid 11.8
Nortriptyline hydrochloride 11.6
3-bromo-4,5-dihydroxybenzaldehyde 11.2
Daphnoretin 10.8
2,4,6-octatrienoic acid 10.8
Aloesin 10.6
Isovitexin 10.0
octyl salicylate 9.9
PQM 9.8
Tectorigenin 9.4
Phytosphingosine 9.4
2,3-DHP 9.4
DFD 9.1
Bixin 9.1
Bixin 9.1
Eusolex 9.0
Aloin 8.8
Isoorientin 8.8
Echinacoside 8.7
Myricitrin 8.7
uroporphyrin I 8.7
Tricin 8.7
Brazilin 8.6
Mycosporine 8.5
Aloin 8.4
2-ethylhexyl acrylate 8.3
Quercitrin 8.3
Glabridin 8.2
WMO 8.1
Arbutin 7.7
Crocetin 7.6
Laminarin 7.6
DHM 7.6
2-phenoxyethanol 7.5
1-indanone 7.4
Kojic acid 7.4
2-methyl-1-butanol 7.4
Galangin 7.4
Fisetin 7.4
1-indanone 7.4
sedoheptulose 7-phosphate 7.3
Dihydromyricetin 7.3
Rifamycin 7.3
Cyanidin 7.3
Astaxanthin 7.3
Phytoene 7.3
Phytoene 7.2
Methylparaben 7.1
Lupeol 7.1
Hesperidin 7.1
DMPE 7.1
Span 80 7.0
azelaic acid 7.0
Histoacryl 7.0
Osthole 6.9
isopropylbenzene 6.9
Melanin 6.9
Glyoxal 6.9
Hesperetin 6.8
Ellagic acid 6.7
HN2 6.7
Naringenin 6.7
Wogonin 6.6
Naringenin 6.6
Fucoidan 6.5
Glycolate 6.5
1,1,2-trichloroethane 6.5
Baicalin 6.4
Apigenin 6.4
4-hydroxyphenylpyruvate 6.4
Ethylene oxide 6.4
isopropyl myristate 6.3
BSH 6.3
Squalene 6.2
HMS 6.2
Ferulic acid 6.2
OCTA 6.2
Phloretin 6.2
Lutein 6.2
Ferulic acid 6.2
more...