UMLS:C0849640 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: UMLS:C0849640 (skin damage)
1,516 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
hairless	123
collagen	114
Sep	94
Mol	51
catalase	43
cytokine	40
superoxide dismutase	35
matrix metalloproteinase	34
p38	33
IL-6	32
p53	31
TNF	28
GSH	27
MMP-1	26
ROS	25
caspase-3	25
MAPK	23
cyclooxygenase-2	23
tumor necrosis factor	20
MMP-9	20
AP-1	19
c-Jun	18
COX-2	18
interleukin-6	17
lactate dehydrogenase	17
glutathione peroxidase	17
Nrf2	17
heme oxygenase-1	15
Bcl-2	15
elastin	14
ERK	14
inducible nitric oxide synthase	13
JNK	13
tyrosinase	12
vascular endothelial growth factor	12
MMP-2	11
metalloproteinase	11
IL-10	11
HSP70	10
IL-8	10
mitogen-activated protein	10
collagenase	10
p21	9
type I collagen	9
myeloperoxidase	9
cyclooxygenase	9
antioxidant enzyme	9
involucrin	8
chemokine	8
erythroid	8
tumor necrosis factor alpha	8
thymus	8
proliferating cell nuclear antigen	8
IFN	8
PI3K	8
filaggrin	7
AKT	7
K10	7
scratch	7
SOD	7
MMP-3	7
p65	7
HO-1	7
xanthine oxidase	7
mast cell	7
heat shock protein	6
creatine kinase	6
IL-4	6
PARP	6
epidermal growth factor	6
histone	6
keratin	6
MMP	6
MMP-13	5
CCD	5
CXCL1	5
cytochrome c	5
all-trans	5
insulin	5
hemoglobin	5

Disease
skin cancer	158
cancer	111
dermatitis	92
tumor	64
melanoma	50
carcinogenesis	46
incontinence	37
incontinence	36
pruritus	28
Contact Dermatitis	28
GSH	27
psoriasis	27
skin disease	26
decubitus	23
atopic dermatitis	20
diabetes	19
carcinoma	16
squamous cell carcinoma	16
photosensitivity	14
basal cell carcinoma	14
keratosis	14
premature aging	14
acne	14
systemic lupus erythematosus	11
cold	11
eczema	11
lupus	9
Dermal	9
xeroderma pigmentosum	9
ischemia	9
tumor growth	8
venous disease	7
hypertension	7
mole	7
venous insufficiency	7
purpura	7
freckles	7
lupus	7
tumorigenesis	7
hyperkeratosis	7
obesity	6
skin tumor	6
sepsis	6
scleroderma	6
rash	6
epidermolysis bullosa	5
dehydration	5
rosacea	5
HIV	5
infectious diseases	5
CCD	5
nonmelanoma skin cancer	5
secondary infection	5
CCD	5
leg ulcers	5
skin ulcers	5
breast cancer	5
aggression	5
telangiectasia	5
fecal incontinence	5
lice	5
cutaneous melanoma	5
intertrigo	5
depression	5
confusion	4
melasma	4
anemia	4
leishmaniasis	4
PCL	4
adenocarcinoma	4
bacterial infection	4
xerosis	3
sepsis	3
glioma	3
mole	3
varices	3
emotional distress	3
PSS	3
fits	3
herpes	3

Enzyme
mitogen-activated protein kinase	62
collagenase	47
catalase	45
superoxide dismutase	38
ERK	21
caspase-3	19
glutathione peroxidase	18
lactate dehydrogenase	18
protein kinase	15
tyrosinase	12
peroxidase	11
NADPH oxidase	8
NADPH oxidase	8
creatine kinase	8
protein kinase C	8
xanthine oxidase	7
MMP-3	7
PARP	7
elastase	7
MMP	6
glutathione reductase	6
DNA ligase	5
DNA ligase	5
MEK	4
ornithine decarboxylase	4
interstitial collagenase	4
luciferase	4
trypsin	4
caspase-9	3
hyaluronidase	3
endonuclease	3
heme oxygenase	3
PRE	3
DCF	3
MAP	3
proteasome	3
ACS	3
acetylcholinesterase	3
hyaluronidase	3
caspase-8	3
TAT	2
plasmin	2
KLK7	2
type III procollagen	2
thioredoxin reductase	2
NO synthase	2
GSK	2
deoxyribonuclease	2
kallikrein	2
protoporphyrinogen oxidase	2
P-glycoprotein	2
focal adhesion kinase	2
phosphatidylinositol 3-kinase	2
porphobilinogenase	2
tryptase	2
cathepsin D	1
lipase	1
aldolase	1
CAO	1
urokinase-type plasminogen activator	1
neutral sphingomyelinase	1
kynureninase	1
ceruloplasmin	1
pectinase	1
PDK1	1
eEF2 kinase	1
phospholipase C	1
matrix metalloproteinase 2	1
vibriolysin	1
cellulase	1
dipeptidyl peptidase IV	1
phosphofructokinase	1
cathepsin G	1
alkaline phosphatase	1
chymotrypsin	1
TPP	1
phenol oxidase	1
AMPK	1
hexosaminidase	1
alanine aminotransferase	1