Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0849640 (skin damage)
 1,516 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
hairless 123
collagen 114
Sep 94
Mol 51
catalase 43
cytokine 40
superoxide dismutase 35
matrix metalloproteinase 34
p38 33
IL-6 32
p53 31
TNF 28
GSH 27
MMP-1 26
caspase-3 25
ROS 25
cyclooxygenase-2 23
MAPK 23
MMP-9 20
tumor necrosis factor 20
AP-1 19
COX-2 18
c-Jun 18
interleukin-6 17
lactate dehydrogenase 17
glutathione peroxidase 17
Nrf2 17
heme oxygenase-1 15
Bcl-2 15
elastin 14
ERK 14
inducible nitric oxide synthase 13
JNK 13
tyrosinase 12
vascular endothelial growth factor 12
MMP-2 11
metalloproteinase 11
IL-10 11
collagenase 10
IL-8 10
mitogen-activated protein 10
HSP70 10
type I collagen 9
cyclooxygenase 9
antioxidant enzyme 9
myeloperoxidase 9
p21 9
erythroid 8
involucrin 8
tumor necrosis factor alpha 8
chemokine 8
proliferating cell nuclear antigen 8
PI3K 8
IFN 8
thymus 8
mast cell 7
MMP-3 7
xanthine oxidase 7
p65 7
HO-1 7
AKT 7
K10 7
scratch 7
filaggrin 7
SOD 7
MMP 6
IL-4 6
PARP 6
creatine kinase 6
histone 6
keratin 6
heat shock protein 6
epidermal growth factor 6
CD4 5
MMP-13 5
MED 5
glutathione reductase 5
PKC 5
DNA repair enzyme 5
EPA 5
hemoglobin 5
CD44 5
insulin 5
cytochrome c 5
SOD1 5
lamp 5
p38 mitogen-activated protein kinase 5
endoplasmic reticulum 5
cage 5
gut 5
poly(ADP-ribose) polymerase 5
SPF 5
ESI 5
all-trans 5
CXCL1 5
metalloprotease 5
CCD 5
Rec 4
ornithine decarboxylase 4
TNF-alpha 4
extracellular signal-regulated kinase 1 4
NMR 4
CO2 4
interleukin 6 4
ERK1 4
Ki-67 4
IgE 4
PSE 4
PLA 4
XPA 4
ATP 4
CCL2 4
epidermal growth factor receptor 4
Superoxide dismutase 4
LDH 4
EGFR 4
MMP1 4
extracellular signal-regulated kinase 4
IL-17 4
GCLC 4
caspase-9 4
PCL 4
TIMP-2 3
STAT3 3
FRAP 3
hyaluronidase 3
polypeptide 3
matrix metalloproteinase 1 3
glycoprotein 3
dilute 3
aquaporin-3 3
CD25 3
xenobiotic 3
Itch 3
SDS 3
thymic stromal lymphopoietin 3
ESR 3
ACS 3
Fas 3
tyrosine kinase 3
fused 3
thrombospondin 3
IL-13 3
serine protease 3
CXCL10 3
CD8 3
photolyase 3
ubiquitin 3
fibronectin 3
MITF 3
CAT 3
nitric oxide synthase 3
granulocyte 3
type I procollagen 3
olfactory 3
proteasome 3
transforming growth factor-beta 3
NIR 3
COX-1 3
interleukin-10 3
more...
Disease
skin cancer 158
cancer 111
dermatitis 92
tumor 64
melanoma 50
carcinogenesis 46
incontinence 37
incontinence 36
Contact Dermatitis 28
pruritus 28
GSH 27
psoriasis 27
skin disease 26
decubitus 23
atopic dermatitis 20
diabetes 19
squamous cell carcinoma 16
carcinoma 16
basal cell carcinoma 14
photosensitivity 14
keratosis 14
premature aging 14
acne 14
systemic lupus erythematosus 11
eczema 11
cold 11
lupus 9
Dermal 9
ischemia 9
xeroderma pigmentosum 9
tumor growth 8
venous insufficiency 7
venous disease 7
lupus 7
mole 7
hyperkeratosis 7
freckles 7
purpura 7
hypertension 7
tumorigenesis 7
rash 6
scleroderma 6
obesity 6
sepsis 6
skin tumor 6
fecal incontinence 5
CCD 5
intertrigo 5
skin ulcers 5
epidermolysis bullosa 5
aggression 5
infectious diseases 5
cutaneous melanoma 5
CCD 5
leg ulcers 5
lice 5
depression 5
HIV 5
breast cancer 5
nonmelanoma skin cancer 5
rosacea 5
dehydration 5
telangiectasia 5
secondary infection 5
adenocarcinoma 4
PCL 4
confusion 4
bacterial infection 4
anemia 4
leishmaniasis 4
melasma 4
osteoporosis 3
SDS 3
PSS 3
mole 3
xerosis 3
sepsis 3
lymphoma 3
herpes 3
SEM 3
vitamin D deficiency 3
skin infection 3
B-cell lymphoma 3
sarcoma 3
atherosclerosis 3
pemphigoid 3
cellulitis 3
vitiligo 3
arthritis 3
CEP 3
graft-versus-host disease 3
hemolytic anemia 3
varices 3
rheumatoid arthritis 3
Lupus 3
glioma 3
tumor progression 3
disseminated intravascular coagulation 3
borderline personality disorder 3
fits 3
phytophotodermatitis 3
emotional distress 3
Diaper dermatitis 2
Irritant contact dermatitis 2
leukemia 2
type 2 diabetes 2
DBA 2
DDP 2
bronchopulmonary dysplasia 2
HRS 2
cataract 2
porphyria cutanea tarda 2
variegate porphyria 2
deep vein thrombosis 2
Thymus 2
Frey 2
photodermatitis 2
AIDS 2
SLE 2
colon cancer 2
T-cell lymphomas 2
candidiasis 2
cystic fibrosis 2
sarcoidosis 2
thymoma 2
Melanoma 2
rhabdomyosarcoma 2
herpes simplex 2
autoimmune disease 2
SCID 2
chronic hepatitis 2
paraplegia 2
seborrheic keratosis 2
Hodgkin's disease 2
HSP 2
cutaneous T-cell lymphoma 2
hemangioma 2
pheochromocytoma 2
Infection 2
epithelioma 2
localized scleroderma 2
thrombocytopenia 2
varicella 2
stroke 2
plaque 2
warts 2
pemphigus 2
multiple myeloma 2
proteinuria 2
MCF 2
Stevens-Johnson syndrome 2
MDI 2
neoplastic transformation 2
porphyria 2
obstructive sleep apnea 2
Chronic GVHD 2
glomerulonephritis 2
coagulopathy 2
cardiovascular disease 2
infestation 2
more...
Symptom
skin damage 1516
erythema 110
pain 41
skin irritation 19
discomfort 14
discomfort 13
dry skin 7
thinning 6
nausea 4
anesthesia 4
splenomegaly 3
analgesia 3
scaly skin 2
hypothermia 2
HSA 2
weakness 2
fatigue 2
arthralgia 2
collapse 2
stigma 1
twitching 1
nasal congestion 1
generalized pain 1
acidity 1
agitation 1
numbness 1
physical appearance 1
cough 1
tremor 1
general problem 1
sleepiness 1
skin impairment 1
stridor 1
blemishes 1
dyspnea 1
No toxic effect 1
photophobia 1
cyanosis 1
anorexia 1
acute stress 1
blurred vision 1
retching 1
penile lesion 1
lethargy 1
belching 1
emaciation 1
Skin thickening 1
skin irritant 1
Wind 1
vomiting 1
seizures 1
flushing 1
myalgia 1
headache 1
abdominal pain 1
hepatosplenomegaly 1
hypoproteinemia 1
Drug
Dermatol 165
ROS 25
vitamin E 22
ascorbate 20
Aloe 9
Vitamin E 5
niacin 4
TiO2 4
caffeine 3
Indomethacin 3
Cardiovasc 3
MAP 3
Mutagen 3
Retinoic acid 3
ZnO 3
citric acid 3
lysine 3
Ethanol 3
Glycyrrhiza 2
TAT 2
Bifidobacterium 2
MRC 2
Monit 2
Red ginseng 2
Photofrin 2
Fraction 2
Heme 2
Ranitidine 2
ADR 2
NADH 2
ETA 2
Sunitinib malate 1
Diclofenac sodium 1
MEA 1
BH4 1
Honey 1
Histamine 1
Fentanyl 1
balanced salt solution 1
Cortisporin 1
ALA 1
CAM 1
Helium 1
Papain 1
CSF 1
Paraffin 1
Photofrin II 1
Imiquimod 1
Capsicum 1
Triclosan 1
Prednisone 1
PTH 1
KGF 1
Monensin 1
Pravastatin 1
Peridex 1
EPA 1
Span 20 1
Peridex 1
DMSA 1
Adriamycin 1
Leaf 1
AZT 1
Gelatin 1
Hydrochlorothiazide 1
Fluorescein 1
Gel 1
ZnCl2 1
Dexrazoxane 1
Clobetasol propionate 1
Eusolex 1
Tocopherol 1
Olive oil 1
Monarch 1
Rutin 1
Ginseng 1
Bexarotene 1
Glutathione 1
Iloprost 1
Diphenhydramine 1
Dial 1
Bromelain 1
Sesame oil 1
Eusolex 1
Ramipril 1
Verteporfin 1
ZnCl2 1
Parsol 1
Vitamin A 1
Doxycycline 1
AZT 1
ACT 1
Carbopol 940 1
Tranilast 1
IFN-gamma 1
Cyanoacrylate 1
Enzyme
mitogen-activated protein kinase 62
collagenase 47
catalase 45
superoxide dismutase 38
ERK 21
caspase-3 19
glutathione peroxidase 18
lactate dehydrogenase 18
protein kinase 15
tyrosinase 12
peroxidase 11
NADPH oxidase 8
protein kinase C 8
creatine kinase 8
NADPH oxidase 8
PARP 7
elastase 7
xanthine oxidase 7
MMP-3 7
MMP 6
glutathione reductase 6
DNA ligase 5
DNA ligase 5
MEK 4
trypsin 4
ornithine decarboxylase 4
interstitial collagenase 4
luciferase 4
caspase-9 3
hyaluronidase 3
endonuclease 3
heme oxygenase 3
PRE 3
acetylcholinesterase 3
MAP 3
proteasome 3
DCF 3
hyaluronidase 3
ACS 3
caspase-8 3
TAT 2
plasmin 2
KLK7 2
type III procollagen 2
porphobilinogenase 2
phosphatidylinositol 3-kinase 2
NO synthase 2
thioredoxin reductase 2
deoxyribonuclease 2
GSK 2
protoporphyrinogen oxidase 2
kallikrein 2
P-glycoprotein 2
focal adhesion kinase 2
tryptase 2
cathepsin D 1
lipase 1
aldolase 1
CAO 1
urokinase-type plasminogen activator 1
neutral sphingomyelinase 1
kynureninase 1
ceruloplasmin 1
pectinase 1
PDK1 1
eEF2 kinase 1
phospholipase C 1
matrix metalloproteinase 2 1
vibriolysin 1
cellulase 1
dipeptidyl peptidase IV 1
phosphofructokinase 1
cathepsin G 1
thermolysin 1
neutrophil collagenase 1
alkaline phosphatase 1
TGT 1
lysin 1
peroxiredoxin 1
TPP 1
phenol oxidase 1
AMPK 1
hexosaminidase 1
thyroid peroxidase 1
chymotrypsin 1
TdT 1
transglutaminase 1
phosphoinositide 3-kinase 1
chitin synthase 1
SPT 1
tissue kallikrein 1
cholinesterase 1
GTP cyclohydrolase I 1
alanine aminotransferase 1
NOS 1
AOR 1
AMP-activated protein kinase 1
macrophage elastase 1
aminopeptidase A 1
cathepsin B 1
MsrA 1
CYP3A4 1
lipoxygenase 1
6-phosphogluconate dehydrogenase 1
cathepsin L 1
AMPK 1
BBE 1
TPP 1
Alternating 1
topoisomerase 1
guanylate cyclase 1
mevalonate kinase 1
transaldolase 1
thrombin 1
cathepsin K 1
6-phosphogluconate dehydrogenase 1
topoisomerase 1
delta-aminolevulinic acid dehydratase 1
Compound
oxygen 190
DNA 157
water 149
Dec 98
Clin 46
sodium 35
GSH 28
GSH 28
TNF 28
hydrogen 26
pyrimidine 24
pyrimidine 24
ethanol 22
acetate 19
vitamin D 15
glucose 14
nitric oxide 14
phosphate 12
iodine 12
calcium 11
sulfate 11
hyaluronic acid 11
8-OHdG 11
iron 11
zinc 10
nitrogen 10
galactose 10
nicotinamide 10
MTT 10
H2O2 9
MDA 9
acetone 8
N-acetylcysteine 8
DPPH 8
cysteine 8
bromide 8
methanol 7
Vitamin E 7
H2S 7
selenium 7
copper 7
PGE 7
octyl 7
octyl 7
retinoic acid 7
octyl 7
PGE2 7
PEG 6
Quercetin 6
serine 6
Collagen 6
Melanin 6
silver 6
Vitamin D 6
diacetate 6
His 6
gallic acid 5
titanium 5
methionine 5
CO2 5
SPF 5
Curcumin 4
Off 4
lysine 4
tryptophan 4
phenol 4
salt 4
ATP 4
Astaxanthin 4
tryptophan 4
nicotinic acid 4
tryptophan 4
Melatonin 4
hydroxide 4
Ascorbic acid 4
tryptophan 4
SDS 4
Silymarin 3
Titanium dioxide 3
Apigenin 3
CAT 3
cAMP 3
anthracene 3
DFD 3
carbonate 3
toluene 3
ADR 3
XPA 3
DDP 3
boron 3
Resveratrol 3
potassium 3
azelaic acid 3
CAT 3
ethyl acetate 3
PLA 3
5-HT 3
isopropanol 3
2-nonenal 3
ACS 3
methane 3
MAP 3
XPA 3
ACS 3
Cortisol 3
CAT 3
creatinine 3
arginine 3
caffeine 3
Fucoidan 2
Phe 2
PDT 2
ADP 2
malic acid 2
NADH 2
DAD 2
Hesperidin 2
Hematoxylin 2
ADP 2
aldehyde 2
Fisetin 2
malic acid 2
MEK 2
THP 2
PEG 2
benzoic acid 2
chalcone 2
chlorine 2
Sodium 2
Span 80 2
Ellagic acid 2
Lutein 2
Naringenin 2
naphthoquinone 2
DBA 2
uroporphyrin I 2
Ferulic acid 2
DBA 2
ADP 2
NAD 2
Celecoxib 2
cadmium 2
naphthoquinone 2
glutamate 2
threonine 2
aldehyde 2
Arsenic 2
3-aminobenzamide 2
dUTP 2
Cyanidin 2
Heme 2
propylene glycol 2
L-DOPA 2
malic acid 2
malic acid 2
naphthoquinone 2
naphthoquinone 2
Tween 80 2
urea 2
Pentoxifylline 2
more...