Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0848771 (neurological disability)
 928 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
KLHL13 11.7
SH3BP4 11.7
protein tyrosine phosphatase receptor type C 11.6
2',3'-cyclic nucleotide 3' phosphodiesterase 11.6
HSPA4L 11.5
NEXN 11.4
HARS2 11.1
N-acetylglucosamine-6-O-sulfotransferase 10.8
RRN3 10.8
tetraspan membrane protein 10.7
EPB41L4A 10.7
LARS2 10.5
Po protein 10.4
DNAJC12 10.4
sphingomyelin synthase 1 10.4
POLR1D 10.4
14-3-3 epsilon protein 10.1
ST3GAL5 10.1
SOS-1 10.1
RPL3 10.0
TMEM119 10.0
CENPJ 10.0
ITPR3 10.0
hematopoietic prostaglandin D synthase 9.9
syntaphilin 9.9
HSPH1 9.9
betaine homocysteine methyltransferase 9.8
PEX12 9.8
neuronal pentraxin 1 9.7
C10orf2 9.7
neurofilament light protein 9.7
DPPX 9.7
LRP130 9.6
MOBP 9.5
COMT protein 9.5
HSP70B 9.5
cystatin D 9.5
CLPP 9.0
HLA-DRB1*15 9.0
Glypican-5 9.0
CDK5RAP2 9.0
PTRF 9.0
CNR2 8.9
LRPPRC 8.9
UCP4 8.9
UCP5 8.9
HSPA6 8.8
TUBA1A 8.7
P2RY12 8.7
VAV1 8.6
DRB1* 8.6
CRASH 8.5
TRKB 8.5
KLK6 8.5
ataxin-7 8.4
MOG 8.4
GP130 8.4
Frataxin 8.4
KLK2 8.4
KLK1 8.2
VDB 8.1
Tissue kallikrein 8.1
Spinocerebellar ataxia type 7 8.1
mGlu3 8.0
QKI 8.0
BACH1 7.9
GM3 synthase 7.9
MCPH1 7.9
HSD17B4 7.8
AAAS 7.8
Caspr2 7.8
S-adenosyl-L-homocysteine hydrolase 7.8
AXIN1 7.8
HSP90AA1 7.8
PSN 7.7
nuclear respiratory factor-1 7.7
CEBPB 7.7
ASPM 7.7
cell adhesion molecule L1 7.7
CNR1 7.6
OGD 7.5
interferon-beta 7.5
collapsin response mediator protein 7.5
brevican 7.5
mGlu2 7.5
MAOB 7.5
group-specific component 7.5
collapsin response mediator protein 2 7.4
CIR 7.4
OLIG2 7.3
myelin oligodendrocyte glycoprotein 7.3
neogenin 7.3
DCI 7.3
ubiquitin C-terminal hydrolase 7.3
methyl CpG binding protein 2 7.2
CMAP 7.2
IL7R 7.2
GalNAcT 7.2
HSP70-1 7.1
IDD 7.1
ALF 7.1
ATP7B 7.0
ATP binding cassette transporter 7.0
OPA1 6.9
TUG 6.9
NLRP1 6.9
HSPA1A 6.9
myosin VI 6.8
PDK4 6.8
chemokine receptor 2 6.8
carnitine palmitoyltransferase 1 6.8
Cyclin-dependent kinase 5 6.7
classical) 6.7
TREM2 6.7
ALD 6.7
DAN 6.7
frataxin 6.6
peroxisomal membrane protein 6.6
RIS 6.6
X-linked adrenoleukodystrophy 6.6
LIS1 6.6
TAG-1 6.5
Fractalkine 6.5
beclin 1 6.5
Notch3 6.5
ATX 6.5
CMT1A 6.5
GAP43 6.5
MSS 6.5
axonal 6.5
IFN-beta 6.4
NOS1 6.4
FBXW7 6.4
TCD 6.4
matrix metalloprotease 6.3
GLT1 6.3
cyclophilin D 6.3
chemokine receptor 4 6.3
activating transcription factor 3 6.3
glutamate receptor subunit 6.3
CCL1 6.3
penumbra 6.3
Wilson disease 6.2
Tissue plasminogen activator 6.2
AGO 6.2
glutamate-cysteine ligase 6.2
Eotaxin 6.2
cannabinoid receptor 1 6.2
TRPM7 6.2
DMT 6.2
CysLT1 6.1
GAA 6.1
CC1 6.1
HPT 6.1
ICAM1 6.1
IKZF1 6.0
MxA 6.0
GBS 6.0
Toll-like receptor 3 5.9
aquaporin 4 5.9
more...
Disease
Multidirectional nystagmus 15.1
Tumorlet 13.1
Progressive multiple sclerosis 12.5
Adhesive arachnoiditis 11.6
Secondary progressive multiple sclerosis 11.6
Spinal cord atrophy 11.5
Retinal atrophy 11.3
Demyelinating disorders 10.7
Hypoxic-ischemic brain injury 10.7
Progressive myoclonic epilepsy 10.7
Primary progressive multiple sclerosis 10.3
Acute posterior multifocal placoid pigment epitheliopathy 10.2
triplegia 10.2
Intermediate uveitis 10.1
Cryptococcal infections 10.1
Reversible posterior leukoencephalopathy syndrome 10.0
Neonatal meningitis 10.0
Cavernous sinus thrombosis 9.9
Balo's concentric sclerosis 9.8
Cervical myelopathy 9.7
secondary cardiomyopathy 9.6
maternal alcoholism 9.6
Relapsing-remitting multiple sclerosis 9.6
Neonatal encephalopathy 9.5
CNS demyelinating disease 9.0
Chronic inflammatory demyelinating polyradiculoneuropathy 8.8
Hypoxic-ischemic encephalopathy (HIE) 8.7
polioencephalomyelitis 8.7
Tuberculous meningitis 8.6
diffuse sclerosis 8.4
pars planitis 8.4
cerebrovascular occlusion 8.3
Neuromyelitis optica 8.3
multiple sclerosis 8.3
Osteoradionecrosis 8.1
Spinal epidural abscess 8.1
CMT1A 8.0
MCPH1 8.0
Ischemic stroke 8.0
leukoencephalitis 7.9
optic neuritis 7.9
Periventricular leukomalacia 7.8
traumatic coma 7.8
periphlebitis 7.8
Adie 7.8
myelomalacia 7.8
PSN 7.7
hereditary motor and sensory neuropathy 7.6
Toxoplasma encephalitis 7.6
Bielschowsky 7.5
pansinusitis 7.5
global aphasia 7.5
Insulinoma 7.4
Middle cerebral artery occlusion 7.4
polyradiculoneuropathy 7.4
encephalomyelitis 7.3
ranula 7.3
GM2 gangliosidosis 7.2
Acute disseminated encephalomyelitis 7.2
IDD 7.1
panuveitis 7.1
AHL 7.0
reactive depression 7.0
AMN 7.0
hemichorea 6.9
memory disorder 6.9
disabling disease 6.9
myelitis 6.8
papillitis 6.8
cervical spondylosis 6.7
OPA1 6.7
subacute sclerosing panencephalitis 6.6
Friedreich's ataxia 6.6
congenital infection 6.6
ALD 6.5
MSS 6.5
Zellweger syndrome 6.4
Multiple system atrophy 6.4
spinal cord compression 6.3
Refsum disease 6.3
pachymeningitis 6.2
Morquio 6.2
REM sleep behavior disorder 6.2
hemangioblastoma 6.2
cerebral abscess 6.2
leukodystrophy 6.2
Autosomal dominant polycystic kidney disease 6.2
MELAS 6.2
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy 6.1
Sandhoff disease 6.1
neuromyotonia 6.1
encephalopathy 6.1
mitochondrial encephalomyopathy 6.0
anomia 6.0
profound mental retardation 6.0
neurological disease 6.0
brain atrophy 6.0
conversion reaction 6.0
lissencephaly 6.0
cerebral vasospasm 6.0
viral meningitis 5.9
choreoathetosis 5.9
MELAS 5.9
ISH 5.9
macrocytic anemia 5.9
LIS1 5.9
Charcot-Marie-Tooth disease 5.9
cerebral palsy 5.9
sensory neuropathy 5.8
hyperphenylalaninemia 5.8
ventriculitis 5.8
autoimmune disease 5.8
Churg-Strauss syndrome 5.8
uvea 5.8
PNS 5.8
leptomeningeal metastases 5.7
nervous system infection 5.7
tension pneumothorax 5.7
POEMS syndrome 5.7
kernicterus 5.6
ganglioglioma 5.6
methylmalonic acidemia 5.6
achondroplasia 5.6
degenerative disease 5.6
tension headache 5.6
mastoiditis 5.6
spastic paraplegia 5.6
dysphasia 5.5
ear disease 5.5
TCD 5.5
optic atrophy 5.5
mononeuropathy 5.5
PMS 5.4
vasospastic angina 5.4
specific language impairment 5.4
siderosis 5.4
arachnoiditis 5.4
Wilson's disease 5.4
cerebral ischemia 5.3
congenital rubella 5.3
Guillain-Barre syndrome 5.3
ABS 5.3
arteriopathy 5.2
GBS 5.2
rectal prolapse 5.2
dysautonomia 5.2
mental handicap 5.2
Hypertrophic cardiomyopathy 5.2
ABS 5.2
polyneuropathy 5.1
brain abscess 5.1
intellectual impairment 5.1
moyamoya 5.1
Bell's palsy 5.0
galactorrhea 5.0
PIC 5.0
hydrocephalus 5.0
mitochondrial myopathy 5.0
spondyloarthropathy 4.9
herniated disc 4.9
more...
Symptom
neurological disability 15.1
meningism 7.7
Neurologic symptoms 7.5
athetosis 7.0
loss of taste 6.5
functional recovery 6.0
halitosis 5.9
dysarthria 5.8
drooling 5.7
exertional angina 5.5
spasticity 5.4
incoordination 5.3
cerebellar ataxia 5.2
paraparesis 5.2
hemiplegia 5.1
muscle rigidity 5.0
hypothermia 5.0
myoclonus 4.6
photophobia 4.4
ophthalmoplegia 4.4
dystonia 4.3
neck pain 4.1
ataxia 4.1
Depressive symptoms 4.1
chorea 4.0
bradykinesia 3.9
spasm 3.8
weakness 3.7
seizures 3.5
fatigue 3.3
tremor 3.2
headache 3.1
thinning 2.6
paresis 2.6
nausea 2.5
agitation 2.5
stigma 2.4
hypercapnia 2.1
distraction 1.9
nausea and vomiting 1.8
dizziness 1.8
insomnia 1.7
cough 1.5
back pain 1.5
vomiting 1.1
pain 1.1
anesthesia 0.9
respiratory distress 0.8
discomfort 0.6
discomfort 0.5
overweight 0.4
analgesia 0.3
collapse 0.3
Drug
Interferon beta-1a 10.0
Ocrelizumab 9.7
Zinc acetate 9.5
Avonex 9.5
Copaxone 8.8
Novantrone 8.4
Isoprinosine 8.3
Natalizumab 8.1
Diamox 7.8
Sinemet 7.3
Pirfenidone 7.2
Sinemet 7.2
Levosimendan 6.8
Felodipine 6.5
Tocilizumab 6.3
CVA 6.2
Sinemet 6.0
Urokinase 5.8
Campath 5.5
Campath 5.5
Rosiglitazone 5.4
Methylprednisolone 5.2
Isoniazid 5.1
Prednisone 5.1
Posture 4.7
Rituximab 4.6
p75 4.1
Check 4.1
Theophylline 4.1
Frontal 4.1
-deoxyadenosine 4.0
Portal 4.0
uPA 4.0
CSF 4.0
Fragment 3.9
TAT 3.8
Nitric Oxide 3.7
IFN-beta 3.5
Vitamin E 3.4
Fluorescein 3.2
ROC 2.1
vitamin E 2.0
IFN-gamma 1.2
lysine 0.8
NADH 0.6
Dial 0.2
Cardiovasc -2.5
Enzyme
GalNAc-T 8.3
GM3 synthase 7.3
NCP 7.1
esterase D 7.1
S-adenosyl-L-homocysteine hydrolase 7.0
DMT 6.1
isopeptidase 5.9
phenylalanine hydroxylase 5.6
gamma-glutamylcysteine synthetase 5.6
GAS 5.2
nucleotidase 5.1
tissue plasminogen activator 4.8
acyl-CoA synthetase 4.7
indoleamine 2,3-dioxygenase 4.6
3-hydroxy-3-methylglutaryl coenzyme A reductase 4.6
aconitase 4.3
botulinum neurotoxin 4.2
PDK1 3.9
matrix metalloproteinase 2 3.9
TAT 3.8
ceruloplasmin 3.8
succinate dehydrogenase 3.7
demethylase 3.6
carboxylesterase 3.5
isocitrate dehydrogenase 3.5
thyroid peroxidase 3.5
CPT 3.4
GSK 3.3
MMP-3 3.3
isocitrate dehydrogenase 3.3
CPT 3.3
enolase 3.2
caspase-9 3.2
MMP 3.0
cytochrome oxidase 3.0
complex I 2.9
CPT 2.9
MIP 2.8
tyrosine hydroxylase 2.8
glutamine synthetase 2.8
adenosine deaminase 2.7
adenosine deaminase 2.7
pyruvate kinase 2.7
urokinase-type plasminogen activator 2.7
pyruvate dehydrogenase 2.6
phosphoinositide 3-kinase 2.5
caspase-3 2.5
kallikrein 2.5
AMPK 2.4
ATP synthase 2.3
NOS 2.2
gamma-glutamyl transpeptidase 1.9
lactate dehydrogenase 1.8
superoxide dismutase 1.8
AMPK 1.5
AMP-activated protein kinase 1.4
PARP 1.3
focal adhesion kinase 1.2
NO synthase 1.1
mitogen-activated protein kinase 1.1
DNA polymerase 1.0
calcineurin 1.0
collagenase 0.9
phosphodiesterase 0.9
luciferase 0.8
glutathione peroxidase 0.6
protein kinase 0.3
ERK 0.1
peroxidase 0.1
RNA polymerase -0.0
Compound
Melarsoprol 9.7
hexacosanoic acid 9.3
Zinc acetate 9.3
Cuprizone 9.2
NDS 8.3
Mitoxantrone 7.8
Mitoxantrone 7.7
DCI 7.2
Nisoldipine 7.1
Triptolide 7.1
Ethambutol 6.9
Edaravone 6.7
Quinolinic acid 6.6
DEG 6.4
Tumor Necrosis Factor 6.3
Phenoxybenzamine 6.3
DMT 6.1
DMT 6.0
Toluidine blue 5.8
Nicardipine 5.8
HMF 5.7
HPT 5.6
Nimodipine 5.5
GD3 5.5
Uridine 5.4
SAH 5.4
PLP 5.4
PMS 5.4
Methylprednisolone 5.3
Acetazolamide 5.3
Evans Blue 5.3
Minocycline 5.2
Eosin 5.1
Wellcome 5.0
N-acetylaspartate 5.0
Dipyridamole 4.9
Dipyridamole 4.9
Dipyridamole 4.9
Dipyridamole 4.9
Glycogen synthase 4.9
Eosin 4.8
MK801 4.8
PEA 4.7
Acetone 4.6
DPA 4.5
DPA 4.5
DPA 4.5
DPA 4.5
DPA 4.5
Prednisone 4.4
Biotin 4.3
GM2 4.3
MMA 4.3
Methionine 4.1
neopterin 4.1
GM3 4.0
Resveratrol 3.9
ASC 3.9
SEE 3.8
Hematoxylin 3.7
Malondialdehyde 3.7
CIT 3.7
S-adenosylhomocysteine 3.6
Theophylline 3.6
Neuronal 3.6
MCA 3.5
MCA 3.5
COX 3.5
CPT 3.4
Quercetin 3.4
5-hydroxytryptophan 3.4
Melatonin 3.4
CPT 3.3
INH 3.3
Tamoxifen 3.3
Tamoxifen 3.2
A 3 3.2
THE 3.1
Vitamin E 3.1
Retard 3.0
fluorine 3.0
Chitosan 2.9
L-DOPA 2.9
chromate 2.9
vitamin D 2.9
UTP 2.9
betaine 2.8
AMPA 2.8
Cyclosporine 2.7
acetate 2.7
strontium 2.7
TNF 2.6
Vitamin D 2.4
DTPA 2.3
Cereb 2.3
6-12 2.3
H2S 2.2
dUTP 2.2
adenosylmethionine 2.0
Optimal 2.0
Dopamine 2.0
TCA 1.9
GMP 1.9
Sodium 1.9
Cholesterol 1.8
NAD 1.8
isoleucine 1.7
isoleucine 1.7
glutamate 1.7
N-acetylcysteine 1.7
nitric oxide 1.6
copper 1.6
homocysteine 1.6
uridine 1.4
His 1.4
NAD 1.4
GlcNAc 1.4
oxygen 1.3
valine 1.2
Thyroid 1.2
TSH 1.2
ASA 1.1
NMDA 1.1
MTT 1.1
acrylamide 1.0
Phe 1.0
GABA 1.0
iron 1.0
GABA 1.0
tryptophan 1.0
tryptophan 1.0
glucose 1.0
tryptophan 0.9
ATP 0.9
ACTH 0.8
methionine 0.8
pyrimidine 0.8
pyrimidine 0.7
tryptophan 0.7
Ile 0.7
cGMP 0.7
acetone 0.7
NADH 0.6
TEM 0.5
MDA 0.5
retinoic acid 0.5
hydroxide 0.5
calcium 0.4
nitrogen 0.4
lysine 0.3
Clin 0.3
zinc 0.2
silver 0.2
Dial 0.1
potassium 0.1
5-HT 0.1
Dec -0.0
acetic acid -0.0
glycerol -0.2
GSH -0.3
more...