Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0848676 (male subfertility)
265 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

DAZ gene deletions at the azoospermia factor (AZF) locus on the Y chromosome, have been implicated as one of the major causes of idiopathic male subfertility. Deletions of the entire DAZ gene have been reported in azoospermia as well as in oligozoospermia. The DAZ gene encodes a RNA binding protein which is expressed exclusively in germ cells. The exact biological role and function of the DAZ protein has yet to be resolved.
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PMID:[From gene to disease; deletion of the DAZ-gene from the Y-chromosome in oligo- or azoospermia ]. 1152 89