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Query: UMLS:C0848676 (male subfertility)
 265 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Subfertility was evaluated in 425 men. Varicocele were diagnosed in 37.4 per cent of these patients and surgical correction of the varicocele in 68 men resulted in a 65 per cent improvement in semen quality. Idiopathic abnormalities were found in 25.4 per cent of the patients. Since the study group was heterogenous setereotyped or empirical treatment cannot hope to be successful if uniformly applied. Other specific causes of male subfertility are identified and therapeutic options are discussed.
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PMID:Experience with 425 subfertile male patients. 2 71

Over the past 25 years the association of varicocele with male subfertility has been repeatedly demonstrated and the beneficial effect of varicocele ligation in infertile men with oligoasthenospermia has been documented. Since the precise mechanisms by which a varicocele affects spermatogenesis are still unclear, the proper approach to the management of "asymptomatic" varicoceles is controversial.
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PMID:Varicocele and male fertility. 32 81

Varicocele is the most common surgically correctable cause of male subfertility. The incidence of varicocele is about the same in adolescents as in men (16.3%). Percutaneous transfemoral sclerotherapy has been performed in 42 of the authors' own cases; it is an alternative to surgical ligation of the varicocele and should be recommended whenever a varicocele is found, to prevent gonadotoxic damage.
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PMID:[Varicocele in childhood. Treatment indications and value of sclerotherapy]. 130 10

The association of clinically apparent varicoceles with male subfertility and infertility has been noted in the urology literature since the late nineteenth century, and surgical ligation of varicoceles has been considered appropriate therapy in an attempt to improve semen quality and increase fertility for the past 40 years. It has been established by several authors cited herein that varicocele size does not predict prognosis after ligation reliably. Because subclinical varicoceles may affect testicular function and histologic characteristics adversely and because age at time of therapy may affect probability of successful enhancement of fertility, the interest of radiologists and urologists has been directed toward diagnosis and treatment of both clinically obvious and clinically occult varicoceles, particularly in young adult men or adolescent boys. Testicular growth after varicocele ligation in adolescent boys also suggests a benefit from early intervention. Sonographic evidence of a varicocele must be correlated with analysis of semen for sperm density, motility, and morphology, as not all patients with varicoceles are infertile. Although surgical therapy is standard for varicocele occlusion, fairly extensive evidence exists to show that percutaneous transvenous occlusion of varicoceles is feasible, safe, and effective, particularly in the setting of varicocele recurrence after conventional surgical treatment.
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PMID:Varicoceles. Radiologic diagnosis and treatment. 202 10

Varicocele is an important cause of male subfertility which may lead to varying degrees of pathological semen quality. Removal of varicocele can be an effective andrological treatment if associated with subfertility. Therefore, in a retrospective study, two possible methods of treatment, high ligation and transcatheter sclerotherapy, were compared with regard to semen parameters and conception rates. Three months after treatment, only high ligation showed a significant improvement of sperm concentration, morphology and motility. Sperm concentration and motility, however, similarly increased in both groups after six to nine months. Sclerotherapy showed a better conception rate of 25% than the surgical group with 14%. Sclerotherapy should be the treatment of first choice if associated with subfertility.
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PMID:Semen parameters and conception rates after surgical treatment and sclerotherapy of varicocele. 224 Jun 23

The management of varicocele is still controversial in spite of its high incidence (15%) in prepubertal boys and young adults and although it is believed to represent a major contributing factor to male subfertility. Fifty boys between 6 and 14 years of age were operated on for left varicocele, and a long segment of the left internal spermatic vein was excised. Thirty-four of them underwent preoperative retrograde left renal venography and pressure readings in both renal veins and inferior vena cava. In all 50 patients, intraoperative antegrade (via internal spermatic vein) left renal venography was performed. This examination revealed impaired renal venous drainage in 38 patients (group A) and normal venous return through the left renal vein in 12 patients (group B). In all 34 patients (from both groups) on whom retrograde venography was performed, there was marked renospermatic reflux. The pressure readings in the left renal vein were significantly increased in group A only. Our data strongly suggest that left varicocele is caused by renospermatic venous reflux and that this condition is probably irreversible. The reflux in group A is explained by the impaired venous drainage through the left renal vein. In group B, it is our impression that the reflux is a result of a congenitally valveless left internal spermatic vein. If varicocele is indeed a major cause for infertility, then our data logically point toward surgery.
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PMID:Varicocele in children: "to treat or not to treat"--venographic and manometric studies. 379 68

The association between varicocele and male subfertility would seem to be borne out by its incidence in the subfertile male population and the presence of disturbances in spermatogenesis, as well as a description of the different physiopathological mechanisms based on renospermatic venous reflux, and the improvement in the sperm and the obtaining of pregnancy after surgical cure of the reflux. The literature on the subject, and the number of successful case reports, have greatly increased in recent years. There is a tendency to extend the surgical indications to include infraclinical forms of varicocele, and even to perform preventive procedures, against male sterility in varicocele-carrying adolescents. In fact, however, there are wide variations in the estimates of the incidence of varicocele, not only in the general population, but also in the female subfertile population. The relationship between sperm characteristics and fertility is difficult to define. While the presence of renospermatic venous reflux is, in most cases, unquestionable, the exact mechanism or mechanisms of its action are uncertain. The efficacy of surgical management itself is variously assessed, and the methodology employed in many studies is open to question. Only an approach based on fertility epidemiological data and comparative studies employing a methodology which is not open to criticism, will ultimately enable us to define the role of varicocele in male subfertility and the role of surgical management in its treatment.
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PMID:[Varicocele and infertility. Facts, uncertainties and hypotheses]. 630 18

A total of 267 cases of male subfertility seen during a three year period beginning April 1980 were studied. The results of treatment for the various groups were analyzed. Good improvement of semen analysis results were obtained for varicocele ligation but pregnancy rates had not yet been studied in detail because of the short span of follow-up. Vaso-vasotomy results had been excellent.
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PMID:Male subfertility--local experience. 652 47

Varicocele is the most frequent cause of male subfertility. Several invasive and noninvasive techniques can be used to visualize scrotal phlebectasies. In this study sequential scintigraphy after intravenous injection of 99mTc-albumin was compared with tele-thermography. The normal and pathological images are described. The more obvious the clinical condition, the more lesions were revealed by scintigraphy (29.6% in subfertile men suspected of having variococele; 76.9% in patients with first degree varicocele; and 100% in Grades II and III cases). In 55 cases (of a total of 76 cases explored by radioisotopic techniques), the comparison of the thermographic results with the scintigraphy results suggests that scrotal scintigraphy is less sensitive. However, there are more false positive thermographies expressed as a discordance with clinical examination, which indicates higher specificity of scintigraphy. In conclusion scrotal scintigraphy cannot be considered as the screening procedure of first choice for varicocele, but it can give complementary information, especially when thermographic results are at variance with the clinical examination.
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PMID:Comparison of scrotal scintigraphy and thermography for the diagnosis of varicocele. 684 Jan 32

Spermatological examinations were performed on 61 patients before and after varicocelectomy. Sperm morphology remained unchanged, but the sperm density increased in 67.2% cases and in 54.1% the sperm motility rose over a period of up to 18 months following the treatment. In 72.1% of the cases an improvement in at least one ejaculate parameter was noted. Of 52 patients who underwent the operation because of infertile marriage, the patient's wife became pregnant in 23.1% following varicocelectomy. Pathogenesis of the varicocele and the problems involved in ligaturing the spermatic vein for male subfertility are discussed.
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PMID:[Spermatological changes after ligature of the spermatic vein for idiopathic varicocele]. 712 60


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