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Query: UMLS:C0848255 (female puberty)
 121 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To determine the effects of prepubertal ethanol (ETOH) exposure on hypothalamic and pituitary hormones known to be involved in the onset of female puberty, we have chronically exposed female rats to either a liquid-diet containing ETOH or an isocaloric control liquid-diet. An additional set of controls consisted of animals maintained on Lab Chow, and water provided ad lib. Our results indicate that the feeding regimen employed produced no differences with regard to body and reproductive organ weights, as well as any of the hormones measured between the two control groups. Conversely, ETOH-treated animals showed significantly lower body and reproductive organ weights than the control animals and although no differences were detected between ETOH-treated and control animals with regard to the hypothalamic content of somatostatin (SRIF), there was a significant increase in the hypothalamic content of growth hormone releasing hormone (GHRH), with a concomitant and significant decrease in the serum concentration of growth hormone (GH). Furthermore, the ETOH-treated animals showed a significant increase in the hypothalamic content of luteinizing hormone releasing hormone (LHRH) with a significant decrease in the serum concentration of luteinizing hormone (LH), but not follicle stimulating hormone (FSH). These results demonstrate for the first time that chronic, prepubertal ETOH administration alters the concentrations of specific hypothalamic and pituitary hormones which are known to be involved in the female pubertal process.
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PMID:Actions of ethanol on hypothalamic and pituitary hormones in prepubertal female rats. 196 48

To assess more closely the physiological mechanism(s) by which ethanol (ETOH) delays the onset of female puberty, we have evaluated its effects on body weight, the vaginal opening (VO)-first diestrus (D1) interval and the serum concentrations of growth hormone (GH), luteinizing hormone (LH) and follicle-stimulating hormone (FSH) throughout the peripubertal period in the rat. Using a specific intragastric feeding regimen, 29-day-old rats began receiving either a liquid diet containing ETOH or an isocaloric control liquid diet. Additional controls consisted of animals maintained on laboratory chow and water provided ad libitum. Animals were either killed between 32 and 37 days of age, categorized with regard to their phase of puberty and their serum hormones measured; or, in some animals, the ETOH liquid diet was administered through day 41 and at that time replaced by the control liquid diet in order to determine if recovery would occur. Our results indicate that ETOH-treated animals showed significantly lower body weights and a significantly longer mean VO-D1 interval than the control animals. Also, serum GH and LH levels were significantly lower in the ETOH-treated animals; however, FSH levels were not affected. Administration of the ETOH liquid diet through day 41 produced varying detrimental effects on the onset of puberty and subsequent removal of ETOH from the diet resulted in rapid growth of the animals, followed by the onset of puberty.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Effects of ethanol during the onset of female puberty. 210 89

Five experiments were conducted to test the effects of the age of urine on the acceleration and delay of puberty in female mice resulting from treatment with urinary chemosignals. The chemosignal in the urine of male mice that accelerates female puberty was not affected by remaining exposed to the air at room conditions for up to 7 days, or when dried in air and reconstituted with water. The chemosignal in the urine of grouped female mice that delays puberty in females and the chemosignal present in the urine of pregnant and lactating female mice that accelerates female puberty were affected to varying degrees by exposure to room conditions; at 5-to-7 days of exposure the urine samples lost their capacity to delay or accelerate sexual maturation. These results are in agreement with earlier work indicating that the male chemosignal is not volatile, whereas the substances in urine from grouped females and pregnant or lactating females are more volatile. The results also have implications for interpretations of how the urinary chemosignals may affect the population biology of house mice under natural conditions.
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PMID:Acceleration and delay of puberty in female mice via urinary chemosignals: age of the urine stimulus. 369 58

The effects of urinary chemosignals influencing reproduction and puberty were studied in free-living house mice maintained in six 0.1-ha outdoor enclosures. Two enclosures were provided with urine and soiled bedding from male mice, two with urine and soiled bedding from group-caged female mice, and two with water and clean bedding as a control. Reproduction, puberty, recruitment, and population size all were affected by the urine treatments. Overall, populations reached significantly greater numbers in the enclosures treated with male urine and soiled bedding, intermediate levels with the water and clean bedding treatment, and were lowest for enclosures treated with urine and soiled bedding from grouped females. The population differences resulted from urinary chemosignal effects on adult female reproduction and female puberty; in general, females were in higher states of reproductive condition, more pregnancies occurred, and young females attained puberty earlier in male-treated enclosures and later in female-treated enclosures than in control enclosures. Urinary chemosignals that affect endocrine physiology and related reproductive processes may be one mechanism by which various factors influence population size in house mice.
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PMID:Urinary chemosignals, reproduction, and population size for house mice (Mus domesticus) living in field enclosures. 2426 68