Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0848237 (
acute stress
)
4,619
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The present study evaluates the effects of
MPTP
-induced striatal DA depletions on sensorimotor behavior in mice. While
MPTP
produces no obvious behavioral deficits under normal conditions,
acute stress
(cold swim) or injection of low doses of haloperidol results in marked akinesia, catalepsy, and sensory neglect. Thus, significant behavioral impairments do accompany the neurotoxicity observed after
MPTP
administration in mice and render this a valuable animal model for studying mechanisms underlying Parkinson's disease.
...
PMID:Acute stress or neuroleptics elicit sensorimotor deficits in MPTP-treated mice. 325 74
