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Query: UMLS:C0848237 (acute stress)
 4,619 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The influence of stress on cardiac electrical stability (CES) and chaotic dynamics of the electrical activity of the heart was studied in acute and chronic experiments in rabbits. Stress was caused by 2-3 h daily immobilization of the animals with electrical stimulation of emotiogenic centers of the hypothalamus through implanted electrodes. CES was estimated by the thresholds for ventricular arrhythmia: paroxysmal ventricular tachycardia, repeated ventricular extrasystoles and ventricular fibrillation (VF). The results showed: (i) CES in stressed rabbits was decreased significantly compared with controls; (ii) the level of chaos at the onset of VF in stressed rabbits was increased significantly compared with controls; (iii) heart rate of stressed rabbits was significantly greater than in controls; (iv) changes in CES parameters depended on whether stress was acute or chronic; (v) acute stress promoted transition of spontaneously reversible VF into spontaneously irreversible VF. Thus, stress increased the degree of disorganization of heart electrical activity and also decreased its electrical stability. The experiments indicate that stress is a destabilizing factor influencing the reversibility of heart rate disorders. The probability of such reversibility depends on whether stress is acute or chronic: acute stress is more likely to lead to irreversible spontaneous VF.
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PMID:Effect of stress induced by electrical stimulation of the hypothalamus on the electrical stability of the heart in rabbits. 1576 16