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Query: UMLS:C0848237 (acute stress)
 4,619 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Initial and follow-up fasting serum glucose levels following acute stroke were evaluated retrospectively in 392 selected hospitalized patients. Transitory reactive hyperglycaemia was observed in a large number of patients (28% of the total series) without a history of diabetes prior to the acute cerebrovascular event. The data from this group suggest a possible relationship between the impairment of carbohydrate metabolism and the type and location of stroke since both the frequency and severity of the hyperglycaemic response were higher in patients with haemorrhagic stroke and brainstem infarction as compared with cerebral infarction. The incidence and degree of the reactive hyperglycaemia were also related to the severity of the acute stroke. There were more comatose patients in the group showing this phenomenon. Initial serum glucose levels in the latter group were higher in unconscious patients than in alert ones. In addition, hospital mortality was significantly higher in these patients. Transitory reactive increases of serum glucose levels were also observed in the majority of patients with a history of overt diabetes prior to the acute stroke. The hyperglycaemic reaction following acute stroke may be attributed to several underlying mechanisms. These include: a non-specific reaction to acute stress and tissue injury with the associated autonomic, hormonal and metabolic alterations; uncovering of underlying latent diabetes by the acute stroke; increased secretion of growth hormone due to stroke-induced hypothalamic dysfunction; and irritation of the glucose regulatory centres in the hypothalamus and brain stem by blood-laden cerebrospinal fluid or local ischaemia.
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PMID:Reactive hyperglycaemia in patients with acute stroke. 97 11

Non-arteriosclerotic (virgin), male and female, Sprague-Dawley rats and arteriosclerotic (breeder), male and female rats were subjected to an acute myocardial infarct when injected with two subcutaneous doses of isoproterenol. Female rats, especially female breeder rats with advanced arteriosclerosis, survived their infarcts in superior fashion to male rats or those with the least severe arterial disease. Animals with severe arteriosclerosis showed the least loss of body weight and greatest increase in heart weight on Day 3 when cardiac necrosis reaches its zenith. Blood pressure and pulse pressure was most seriously reduced in animals with no or early arteriosclerosis only, being best maintained in the animals with the most severe arterial disease. Heart rate was not greatly altered in any of the various groups. Ventricular function, i.e., cardiac output, stroke volume, cardiac index, and left ventricular minute work, was severely impaired in the non-arteriosclerotic animals and in those with the least arterial disease. Total peripheral resistance was also least elevated and myocardial contractile strength (peak flow and max dF/dt) was greatest in female breeders with the most advanced arterial disease. Most intriguing, is the seemingly paradoxical but consistent finding that female breeders which develop the most severe arterial disease are able to best maintain cardiac function during the acute stress of myocardial ischemia.
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PMID:Hemodynamic changes in arteriosclerotic vs. non-arteriosclerotic rats during the acute stages of myocardial infarction. 105 62

The heart includes systolic and diastolic components. The immediate effects of physical activity include increased sympathetic nervous and related hormonal activity; increased heart rate, contractility, stroke volume, and cardiac output. The time for systole and diastole are reduced, with relatively more work per beat. Light activity prior to the following strenuous exertion enhances performance, safety, and recovery. Children, women, and men show similar responses to activity: acute stress, with long-term improvements in cardiovsacular function. There is no cardiovascular reason for restricting activity for children or women. Mental and/or emotional stressors cause similar stress reactions, without the potential long-range benefits of regular physical activity. Athletics is viewed as an optional part of a lifetime of regular, vigorous activity, and as such can make a contribution to one's cardiovascular fitness. From this viewpoint, there is no need to put one in the stressful athletic situation until adequate pre-conditioning has taken place. Neither is there a place for inactive promoters of athletics for its own sake.
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PMID:Athletics and cardiovascular health. 124 Oct 68

1. Twenty-four hour ambulatory blood pressure monitoring (ABPM) was used to evaluate the blood pressure (BP) changes in acute stroke. 2. Stroke was categorized according to the probable underlying vascular mechanism into lacunar infarction (L), thrombotic infarction (T) and intracerebral haemorrhage (ICH). A total of 37 stroke patients were studied (T = 21, L = 9, ICH = 7). Control patients (n = 15) were acute medical admissions not severely ill or in significant pain. ABPM was performed on day 1 and day 7 following admission. 3. Day 1 mean +/- s.d. 24 h systolic BP (SBP) were L (159 +/- 15.8), ICH (151 +/- 33.4), T (147 +/- 15.2) and controls (134 +/- 17.8). Day 7 mean 24 h SBP were L (138 +/- 9.8), ICH (143 +/- 26.9), T (138 +/- 19) and controls (134 +/- 14.8). In each stroke group BP fell to levels similar to control on day 7, while control mean SBP remained unchanged between days 1 and 7. The highest day 1 BP and the greatest subsequent fall on day 7 occurred for lacunar infarction. Diastolic BP showed similar changes to SBP. 4. The acute stress of hospitalization does not appear to explain elevated BP in acute stroke. Lacunar infarction appears to be particularly associated with temporary BP elevation.
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PMID:24 hour ambulatory blood pressure profiles in the acute phase of stroke. 857 17

OBJECTIVES: To determine relationships among ethnicity, reactivity to acute stress and psychologic characteristics. DESIGN: We measured cardiovascular parameters and catecholamine levels at rest and after stress in a group of black and white men and women (45 blacks and 40 whites). METHODS: Blood pressure, heart rate, stroke volume, total peripheral resistance and catgecholamine measures of reactivity to a speaking stressor task were recorded. Multiple regression analysis was used to examine relationships between stress responsivity and psychologic characteristics in black and white subjects. RESULTS: Repeated-measures analysis of variance indicated that systolic and diastolic blood pressure reactivity was lower in blacks than in whites (P < 0.01). A multiple regression model that treated reactivity as a function of psychologic attributes and ethnicity suggested that psychologic attributes differentially affect racial physiologic reactivity. For example, expression of anger was related to lower blood pressure changes in whites but higher blood pressure changes in blacks. Conversely, hostility was related to increased blood pressure reactivity in whites but lower blood pressure reactivity in blacks. Greater task-induced changes in heart rate and stroke volume were related to higher depression scores in blacks but lower depression scores in whites. In addition, the relationship between coping style, anger, anxiety, and stress and catecholamine reactivity in blacks and whites. CONCLUSION: Our findings support those of previous studies; we identified racial differences in stress reactivity and psychologic characteristics that affect reactivity differently in blacks and whites.
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PMID:Acute psychologic stress reactivity in blacks versus whites:relationship to psychologic characteristics. 1022 98

The study comprised 32 patients who were with clinically, laboratory and neuroradiologically confirmed associated occurrence of acute stress disorder and stroke. All the examinees were civilians exposed to war stress, so it could be directly designated as the cause of acute stress disorder and indirectly denoted as a trigger of cardiovascular, endocrine and cerebrovascular disorder that brought to stroke.
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PMID:[Association of manifestations of acute stress disorder and acute cerebrovascular disease]. 1133 55

This study examined the effects of a 3-day enhanced hydration regimen on resting cardiac function and reactivity to acute stress. Healthy volunteers (14 male, 14 female) were assigned to one of two groups: Enhanced Hydration and Normal Hydration Group. Participants in the Enhanced Group were given six 1-l bottles of water and instructed to drink two bottles a day in addition to normal fluid intake for 3 days preceding their laboratory session; no extra water was given to the Normal Group. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), cardiac output (CO), stroke volume (SV), and total peripheral resistance (TPR) were recorded during a 10-min baseline, 6-min Paced Auditory Serial Addition Test (PASAT), 5-min recovery, 5-min intermediate baseline, and 3-min Cold Pressor Test. Repeated-measures ANOVA revealed a significant Hydration GroupxTask interaction for DBP during the cold pressor (p<0.01) with the Enhanced Group exhibiting greater DBP reactivity to cold stress relative to the Normal Group. Analysis revealed significant Hydration GroupxGender interactions for SV and TPR (p<0.05) at rest and during both the PASAT and Cold Pressor Test. Females in the Enhanced Group displayed higher SV and lower TPR relative to Enhanced Group males, whereas females in the Normal Group displayed lower SV and greater TPR relative to Normal Group males. These results suggest that 3-day hydration enhancement influences blood pressure reactivity in both men and women, and that long-term hydration enhancement is related to resting gender differences in cardiac function.
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PMID:Hydration status and cardiovascular function: effects of hydration enhancement on cardiovascular function at rest and during psychological stress. 1572 92

A number of studies have found that increasing lead exposure is associated with increases in blood pressure in humans. Studies with animals suggest that lead-induced increases in vascular resistance account for these increases in blood pressure. The present study assessed cardiovascular functioning at rest and in response to acute stress for 9(1/2) year old children (N=122) having relatively low prenatal (cord) blood lead levels (M=1.98 microg/dL, SD=1.75) and low postnatal (early childhood) blood lead levels (M=4.62 microg/dL, SD=2.51). Higher cord blood levels were associated with higher baseline systolic blood pressure (SBP), and higher early childhood lead levels were associated with greater total peripheral (vascular) resistance (TPR) responses to acute stress. In addition, a negative association between blood lead levels and stroke volume (SV) suggests that lead-induced increases in vascular resistance were sufficient to produce cardiac afterload, a situation arising when blood pressure in the aorta makes it difficult for the left ventricle to eject blood. These effects were not mediated by differences in task performance or emotional responses to the acute stress tasks. Finally, these effects were significant for lead levels considered low, notably, below the 10 microg/dL threshold currently adopted by the CDC for deleterious effects.
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PMID:Prenatal and early childhood blood lead levels and cardiovascular functioning in 9(1/2) year old children. 1591 79

This study was designed to assess the effects of nicotine and nicotine withdrawal on stress-induced hemoconcentration and cardiovascular reactivity during acute stress in smokers. Forty-six smokers (>or=10 cigarettes per day) were tested twice, once while wearing a 21 mg nicotine patch for 12h and once while wearing a placebo patch (nicotine withdrawal). Calculated plasma volume, hemoglobin, hematocrit, HR, SBP, DBP, cardiac output, stroke volume, and total peripheral resistance were assessed during a 10-min baseline period, 6-min Paced Auditory Serial-Addition Task (PASAT), and a 2-min cold pressor (CP). No differences between conditions were found for any of the hematological measurements. Participants demonstrated greater HR and SBP increases to the PASAT during the nicotine withdrawal condition. For CP, participants showed greater HR and DBP increases and SV decreases during the nicotine withdrawal condition. Data from affective state ratings indicated that participants reported more negative affect during the psychological challenges during nicotine withdrawal conditions. Negative affective state may further lead to enhanced cardiovascular reactivity. These results demonstrate that although nicotine and nicotine withdrawal significantly have differential effects on cardiovascular functioning, the same differential condition effects do not appear to exist for stress-induced hemoconcentration.
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PMID:Nicotine and acute stress: effects of nicotine versus nicotine withdrawal on stress-induced hemoconcentration and cardiovascular reactivity. 1618 27

A number of studies have considered whether background stress affects cardiovascular responses to acute stress tasks. The present study considers the effect of a potent background stressor with a clear onset, namely the terrorist attacks on September 11, 2001. Specifically, the authors investigated differences among 9.5-year-old children tested before (N = 30) and then following (N = 20) the 9/11 attacks. In addition, a majority of these children (N = 37) were retested approximately 1 year later (i.e., before and after 9/11/2002). Children tested directly following 9/11/2001 exhibited significantly greater stroke volume and cardiac output responses to acute stress tasks compared with their responses 1 year later, and this change in reactivity differed significantly from the change in reactivity exhibited by children tested before 9/11/2001 and again 1 year later. These results suggest that a potent background stressor can temporarily heighten some children's cardiovascular responses to subsequent acute stressors.
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PMID:Terrorism and cardiovascular responses to acute stress in children. 1628 5


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