Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0847097 (acidity)
 15,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In pigs treated with various doses of prednisone, pathologic changes appeared in the glandular region of the stomach, mainly in the fundic area and rarely and less severely in the cardiac and pyloric mucosae. The characteristic lesion was hemorrhagic gastritis; this was associated with massive gastric hemorrhages in pigs given the larger doses of prednisone. Epithelial changes were found in the esophageal area, but there were no ulcers. In pigs with gastric fistulas, prednisone administered at dose levels of 10 mg/kg of body weight for 8 days produced a significant increase in the volume and the acidity of gastric secretion. Hexosamine output, but not concentration, increased significantly during the treatment period. Change in pepsin secretion was sit significant. Prednisone did not produce an immediate change in gastric secretion--there being a latent period lasting 1 to 2 days before marked changes were observed. After peak changes occurred (3rd or 4th day of treatment), acidity gradually decreased to pretreatment level toward the end of the treatment period. This indicates that although increased acidity may be involved in the development of lesions in the glandular region, other factors probably have a role also in the pathogenesis of steroid-induced stomach lesions in swine.
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PMID:Effects of prednisone on gastric secretion and development of stomach lesions in swine. 109 Feb 20

The purpose of this study was to evaluate the entire cost of nursing staff-prepared thickened liquids with Resource ThickenUp vs. utilizing commercially prepared thickened liquids in an acute care hospital. Time, cost, and effectiveness were studied in a 37-bed adult acute care neuroscience patient care unit in a large urban community hospital. Registered nurses and patient care technicians experienced in mixing thickened liquids for patients with dysphagia created liquids thickened to the consistency of nectar and honey from water, milk, and orange juice. Commercially prepared thickened liquids were 44% to 59% less expensive than the cost of manually creating the thickened liquids. Commercially prepared thickened liquids were more effective and of consistent viscosity than manually prepared thickened liquids due to variability in the skill of the preparer, alteration in the viscosity of the product based on acidity, protein, or sit-time from preparation to consumption.
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PMID:Cost and effectiveness analysis using nursing staff-prepared thickened liquids vs. commercially thickened liquids in stroke patients with dysphagia. 2044 81