Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0847097 (
acidity
)
15,165
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Eukaryotic cells contain organelles bounded by a single membrane in the cytoplasm. These organelles have differentiated to carry out various functions in the pathways of endocytosis and exocytosis. Their lumina are acidic, with pH ranging from 4.5 to 6.5. This article describes recent studies on these animal cell organelles focusing on (1) the primary proton pump (
vacuolar-type H(+)-ATPase
) and (2) the functions of the organelle luminal
acidity
. We also discuss similarities and differences between
vacuolar-type H(+)-ATPase
and F-type ATPase. Our own studies and interests are emphasized.
...
PMID:Luminal acidification of diverse organelles by V-ATPase in animal cells. 1060 Jun 79
