Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0847097 (acidity)
 15,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A rise in fetal acidity (FAS) occurs often but does not necessarily mean that the fetus is at risk. When an increase in acidity is due to maternal causes, a so-called maternogenous increase in acidity (MAS), the fetus has too much organic acid, but no O2 insufficiency. In order to avoid unnecessary operations in such cases, we asked ourselves how we could differentiate on a routine basis between maternogenous and fetogenous acidity increase, and which consequences can be drawn from this. We made observations on 858 neonates with a NApH actual less than 7.30, born between 1973 and 1980 at the Department of Obstetrics at Berlin- Neuk olln Hospital, to assess whether infants with MAS and NapH levels were less often clinically depressed than infants with FAS, and how often an MAS occurred corresponding to Saling 's definition (M/F delta pH qu40 less than or equal to 0.05) to Rooth 's definition (M/F delta pH actual less than or equal to 0.15) or a combination of Saling 's and Rooth 's definition. It was shown that MAS infants were significantly less often born in a clinically depresses state than FAS infants. Within the definition groups there were only very slight differences. With the aid of the Saling and the Rooth combination however, 45% could be recognized as MAS infants, whereas the MAS frequency according to Saling alone or Rooth alone amounted to only about 30%. For the subsequent assessments of the pH levels during labor therefore the combination of Saling and Rooth was used. From 288 labors it could be shown that the differentiation in MAS and FAS in FBA pH levels less than 7.30 led to a significant decrease in the number of operations without any increase in early morbidity in the infants. This leads to the assumption that the procedure described helps to prevent unnecessary operations.
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PMID:[Rise of fetal acidity due to the mother sub partu and its clinical consequences]. 653 38