Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0847097 (acidity)
15,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Both chlorpromazine and NSD-1055 (a non-steroidal anti-inflammatory drug) markedly lower the volume and acidity of gastric contents of rats subjected to pyloric ligation (Shay technique) and reduce the degree of ulceration in the stomach. On the other hand, aminoguanidine (an inhibitor of histaminase) has no effect on acid secretion or ulceration in these animals.
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PMID:Effect of aminoguanidine, chlorpromazine and NSD-1055 on gastric secretion and ulceration in the Shay rat. 554 58